Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000462083> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2000462083 abstract "Background: According to the pathology and general resection specimens, so many patients have breast tumors together with deposited milk. Therefore, we performed this retrospective study to determine the distribution and characteristics of breast diseases in women undergoing mammary ductoscopy and explore the clinical values and implications of mammary ductoscopy in the management of the breast diseases. Materials & Methods: Total of 10,082 women(20,082 breasts) with a mean age of 39.2 years old (ranging from 12 to 84 years old) underwent mammary ductoscopy from 2002 to 2011. We studied NSND in contrast with SND duct, specially focused on the situation of duct with intraductal mass. Comparing with the pathology, we studied the relationship between duct milk deposition and epithelial hyperplasia. Results: From this study we concluded that duct milk deposition was a common disease in 25–59 years old women, it occupied 42.89% cases of the mammary ductal disease and almost 46% are NSND. The character of deposited milk became solid from liquid with the age growing up. Duct milk deposition 476/1431(33.26%)was mostly associated with intraductal masses(total 1431 cases), followed by duct dilatation 517/1431(36.13%). Pathology of patients diagnosed by FDS for duct milk deposition are epithelial hyperplasia(100%), adenosis(86.5%), chronic inflammation(8.8%), metaplasia(16.9), florid hyperplasia(10.8%), tumor-like hyperplasia (57.2%), intraductal tumor or fibroadenoma (27.8%), dysplasia (3.0%), breast cancer (11.7%). Discussion: Diagnosis of duct milk deposition, which may not necessarily presented by nipple discharge, is the most common finding and associated with proliferation and thus intraductal mass, etc. we should noticed 30–50 years old women groups, cause they have have stopped breast-feeding for years but still had yellow or brown, liquid or solid milk-like things in their lactiferous ducts. We predict duct milk deposition may be related with breast carcinogenesis. It is a kind of long time mechanical stimulation in the duct, both the physico-chemical properties and the acid-alkaline environment had changes by years. Still, the deposited milk would be a best medium for microbial and virus, which would cause the genesis of hyperplasia even breast cancer. Therefore, we should go on the research of deposited milk and the changes of the microenvironment of the duct to find the pathogenesis of breast disease. Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-03-03." @default.
- W2000462083 created "2016-06-24" @default.
- W2000462083 creator A5003120193 @default.
- W2000462083 creator A5010518834 @default.
- W2000462083 creator A5071891964 @default.
- W2000462083 creator A5090802873 @default.
- W2000462083 date "2012-12-15" @default.
- W2000462083 modified "2023-09-25" @default.
- W2000462083 title "Abstract P1-03-03: milk deposition in women's mammary duct has been a potential risk factor of breast tumor" @default.
- W2000462083 doi "https://doi.org/10.1158/0008-5472.sabcs12-p1-03-03" @default.
- W2000462083 hasPublicationYear "2012" @default.
- W2000462083 type Work @default.
- W2000462083 sameAs 2000462083 @default.
- W2000462083 citedByCount "0" @default.
- W2000462083 crossrefType "proceedings-article" @default.
- W2000462083 hasAuthorship W2000462083A5003120193 @default.
- W2000462083 hasAuthorship W2000462083A5010518834 @default.
- W2000462083 hasAuthorship W2000462083A5071891964 @default.
- W2000462083 hasAuthorship W2000462083A5090802873 @default.
- W2000462083 hasConcept C121608353 @default.
- W2000462083 hasConcept C126322002 @default.
- W2000462083 hasConcept C142724271 @default.
- W2000462083 hasConcept C2775894508 @default.
- W2000462083 hasConcept C2776524808 @default.
- W2000462083 hasConcept C2777562237 @default.
- W2000462083 hasConcept C2778001805 @default.
- W2000462083 hasConcept C2779141538 @default.
- W2000462083 hasConcept C2779880527 @default.
- W2000462083 hasConcept C2780472235 @default.
- W2000462083 hasConcept C2780898380 @default.
- W2000462083 hasConcept C2781212128 @default.
- W2000462083 hasConcept C530470458 @default.
- W2000462083 hasConcept C71924100 @default.
- W2000462083 hasConceptScore W2000462083C121608353 @default.
- W2000462083 hasConceptScore W2000462083C126322002 @default.
- W2000462083 hasConceptScore W2000462083C142724271 @default.
- W2000462083 hasConceptScore W2000462083C2775894508 @default.
- W2000462083 hasConceptScore W2000462083C2776524808 @default.
- W2000462083 hasConceptScore W2000462083C2777562237 @default.
- W2000462083 hasConceptScore W2000462083C2778001805 @default.
- W2000462083 hasConceptScore W2000462083C2779141538 @default.
- W2000462083 hasConceptScore W2000462083C2779880527 @default.
- W2000462083 hasConceptScore W2000462083C2780472235 @default.
- W2000462083 hasConceptScore W2000462083C2780898380 @default.
- W2000462083 hasConceptScore W2000462083C2781212128 @default.
- W2000462083 hasConceptScore W2000462083C530470458 @default.
- W2000462083 hasConceptScore W2000462083C71924100 @default.
- W2000462083 hasLocation W20004620831 @default.
- W2000462083 hasOpenAccess W2000462083 @default.
- W2000462083 hasPrimaryLocation W20004620831 @default.
- W2000462083 hasRelatedWork W2004582879 @default.
- W2000462083 hasRelatedWork W2009086898 @default.
- W2000462083 hasRelatedWork W2018396463 @default.
- W2000462083 hasRelatedWork W2039221643 @default.
- W2000462083 hasRelatedWork W2046600845 @default.
- W2000462083 hasRelatedWork W2051213316 @default.
- W2000462083 hasRelatedWork W2059949107 @default.
- W2000462083 hasRelatedWork W2066160249 @default.
- W2000462083 hasRelatedWork W2069195511 @default.
- W2000462083 hasRelatedWork W2103396040 @default.
- W2000462083 hasRelatedWork W2248091909 @default.
- W2000462083 hasRelatedWork W2306939951 @default.
- W2000462083 hasRelatedWork W2349104823 @default.
- W2000462083 hasRelatedWork W2367779690 @default.
- W2000462083 hasRelatedWork W2391113933 @default.
- W2000462083 hasRelatedWork W2410522264 @default.
- W2000462083 hasRelatedWork W2488071853 @default.
- W2000462083 hasRelatedWork W2551962713 @default.
- W2000462083 hasRelatedWork W2798580196 @default.
- W2000462083 hasRelatedWork W303614479 @default.
- W2000462083 isParatext "false" @default.
- W2000462083 isRetracted "false" @default.
- W2000462083 magId "2000462083" @default.
- W2000462083 workType "article" @default.