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- W2000463365 endingPage "460" @default.
- W2000463365 startingPage "449" @default.
- W2000463365 abstract "Two decades of research into the role of immunosuppression and angiogenesis in tumor biology have revealed multiple links between the two. Vascular endothelial growth factor, originally thought to be solely involved in vascular growth and permeability, has emerged as a significant agent of immune tolerance in the tumor microenvironment. This review examines two major elements of this field: the research behind the role of vascular endothelial growth factor in immunosuppression, especially as pertains to dendritic cell function; and the subsequent research into the potential for using antiangiogenic therapy to both starve tumors by hypoxia and enhance the response of tumors to immunotherapy. Several strategies tested so far have yielded incomplete, yet promising, results." @default.
- W2000463365 created "2016-06-24" @default.
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- W2000463365 creator A5081827280 @default.
- W2000463365 date "2007-03-21" @default.
- W2000463365 modified "2023-10-10" @default.
- W2000463365 title "Vascular endothelial growth factor and immunosuppression in cancer: current knowledge and potential for new therapy" @default.
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- W2000463365 doi "https://doi.org/10.1517/14712598.7.4.449" @default.
- W2000463365 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17373897" @default.
- W2000463365 hasPublicationYear "2007" @default.
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