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- W2000464357 abstract "Immersion of goldfish, Carassius auratus, in 1 mg∙L −1 phenylhydrazine hydrochloride at 5 °C for 48 h led to reductions of 90–95% in hemoglobin and hematocrit within 10–14 days. Under similar conditions, 96-h exposures prompted heavy mortality. Fewer mortalities occurred after 24-h exposure periods; however, only modest reductions in O 2 -carrying capacity were seen. All higher concentration (2, 5, 10, 50 mg∙L −1 ) and temperature (10, 15, 20 °C) combinations led to complete mortality within 12–96 h regardless of exposure period (24, 48, 96 h). Exposure to phenylhydrazine hydrochloride caused decreases in hemoglobin and hematocrit, changes in the abundances of specific hemoglobin isomorphs, and the transient appearance of novel hemoglobin mobilities as well as evidence of osmo- and iono-regulatory dysfunction. Slow warming to 20 °C prompted red cell proliferation and hemoglobin synthesis and restoration of typical hemoglobin isomorph abundances. Incidence of transfer stresses was monitored by reference to differential leucocyte counts. Transfer led to lymphopenia and thrombopenia with neutrophilia and eosinophilia. Warming was accompanied by increases in lymphocyte and thrombocyte counts and reductions in those of monocytes and all granulocytes." @default.
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- W2000464357 date "1988-03-01" @default.
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- W2000464357 title "Induction of anemia in goldfish, <i>Carassius auratus</i> L., by immersion in phenylhydrazine hydrochloride" @default.
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- W2000464357 doi "https://doi.org/10.1139/z88-108" @default.
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