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- W2000464770 abstract "Endosialidase NF (endoNF) is a bacteriophage-derived endosialidase that specifically degrades α-2,8-linked polysialic acid. The structure of a new crystal form of endoNF in complex with sialic acid has been refined at 0.98 Å resolution. The 210 kDa homotrimeric multi-domain enzyme displays outstanding stability and resistance to SDS. Even at atomic resolution, only a minor fraction of side chains possess alternative conformations. However, multiple conformations of an active-site residue imply that it has an important catalytic function in the cleavage mechanism of polysialic acid." @default.
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- W2000464770 date "2010-01-22" @default.
- W2000464770 modified "2023-10-18" @default.
- W2000464770 title "Structure analysis of endosialidase NF at 0.98 Å resolution" @default.
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- W2000464770 doi "https://doi.org/10.1107/s0907444909048720" @default.
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