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- W2000473340 abstract "That a decreased carbohydrate tolerance accompanies acromegaly was conclusively shown by Davidoff and Cushing. 1 In view of their observations it is not surprising to find the incidence of diabetes mellitus high in this condition. John 2 reported three cases of this kind, in two of which the onset of acromegaly preceded the onset of diabetes. The fact that pituitary extract has an antagonistic action to insulin 3 has brought up the question of whether the diabetes is a true diabetes or the result of an interference with the normal action of insulin. In some cases it would seem that there is a relative, rather than a true, pancreatic deficiency. In others, however, there is little doubt that the diabetes is a true diabetes mellitus, the acromegaly possibly being the original factor in causing the diabetes. Joslin 4 pointed out that the chromophilic cells of the pituitary exert a partially controlling influence on the" @default.
- W2000473340 created "2016-06-24" @default.
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- W2000473340 date "1931-02-01" @default.
- W2000473340 modified "2023-09-25" @default.
- W2000473340 title "ACROMEGALY WITH DIABETES MELLITUS AND XANTHOMA DIABETICORUM" @default.
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- W2000473340 doi "https://doi.org/10.1001/archinte.1931.00140200172010" @default.
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