Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000473408> ?p ?o ?g. }
- W2000473408 endingPage "212" @default.
- W2000473408 startingPage "205" @default.
- W2000473408 abstract "Chronic antidepressant treatment is associated with sexual side effects, particularly affecting the ejaculatory response. Bupropion (BP), an antidepressant inhibiting dopamine/noradrenaline reuptake, seems to have a low impact upon male sexual function. Ejaculation is regulated both at the brain and spinal cord by the spinal generator for ejaculation (SGE). We investigated the effects of chronic BP treatment on ejaculatory behavior and on SGE functioning. Sexually experienced male rats were intraperitoneally (i.p.) injected with BP (7.5 or 15 mg kg−1) during 14 days and tested for sexual behavior on days 1, 7 and 14 of treatment; these same males were used to evaluate the functioning of the SGE by recording the genital motor pattern for ejaculation (GMPE). Acute and chronic BP administration did not importantly modify copulatory behavior of male rats. Chronic treatment with the low dose of BP produced deficits in the functioning of the SGE that were restored by activation of the SGE through afferent stimulation. Conversely, chronic treatment with the high-dose of BP disrupted the functioning of the SGE, as the deficits were not compensated by activating the SGE through sensory stimulation. It is concluded that chronic BP at high doses alters the functioning of the SGE." @default.
- W2000473408 created "2016-06-24" @default.
- W2000473408 creator A5011069874 @default.
- W2000473408 creator A5012288395 @default.
- W2000473408 creator A5081569469 @default.
- W2000473408 date "2014-05-01" @default.
- W2000473408 modified "2023-09-25" @default.
- W2000473408 title "Effects of bupropion on the ejaculatory response of male rats" @default.
- W2000473408 cites W1549251954 @default.
- W2000473408 cites W1565426328 @default.
- W2000473408 cites W1581037063 @default.
- W2000473408 cites W1965227087 @default.
- W2000473408 cites W1979022452 @default.
- W2000473408 cites W1984538112 @default.
- W2000473408 cites W1994717858 @default.
- W2000473408 cites W1998573934 @default.
- W2000473408 cites W1999036944 @default.
- W2000473408 cites W2001156662 @default.
- W2000473408 cites W2004144878 @default.
- W2000473408 cites W2004987315 @default.
- W2000473408 cites W2005568701 @default.
- W2000473408 cites W2010776371 @default.
- W2000473408 cites W2019656158 @default.
- W2000473408 cites W2023597280 @default.
- W2000473408 cites W2033944150 @default.
- W2000473408 cites W2039680025 @default.
- W2000473408 cites W2044661890 @default.
- W2000473408 cites W2046809238 @default.
- W2000473408 cites W2051751584 @default.
- W2000473408 cites W2056436647 @default.
- W2000473408 cites W2056507785 @default.
- W2000473408 cites W2060846672 @default.
- W2000473408 cites W2073435606 @default.
- W2000473408 cites W2074243312 @default.
- W2000473408 cites W2076023426 @default.
- W2000473408 cites W2076227526 @default.
- W2000473408 cites W2076768432 @default.
- W2000473408 cites W2078589457 @default.
- W2000473408 cites W2092055931 @default.
- W2000473408 cites W2092114190 @default.
- W2000473408 cites W2121568571 @default.
- W2000473408 cites W2126074061 @default.
- W2000473408 cites W2128790667 @default.
- W2000473408 cites W2136137449 @default.
- W2000473408 cites W2171466849 @default.
- W2000473408 cites W4318599055 @default.
- W2000473408 doi "https://doi.org/10.1038/ijir.2014.12" @default.
- W2000473408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24784893" @default.
- W2000473408 hasPublicationYear "2014" @default.
- W2000473408 type Work @default.
- W2000473408 sameAs 2000473408 @default.
- W2000473408 citedByCount "3" @default.
- W2000473408 countsByYear W20004734082016 @default.
- W2000473408 countsByYear W20004734082017 @default.
- W2000473408 countsByYear W20004734082020 @default.
- W2000473408 crossrefType "journal-article" @default.
- W2000473408 hasAuthorship W2000473408A5011069874 @default.
- W2000473408 hasAuthorship W2000473408A5012288395 @default.
- W2000473408 hasAuthorship W2000473408A5081569469 @default.
- W2000473408 hasBestOaLocation W20004734081 @default.
- W2000473408 hasConcept C126322002 @default.
- W2000473408 hasConcept C134018914 @default.
- W2000473408 hasConcept C142724271 @default.
- W2000473408 hasConcept C24998067 @default.
- W2000473408 hasConcept C2775871022 @default.
- W2000473408 hasConcept C2777812360 @default.
- W2000473408 hasConcept C2777843972 @default.
- W2000473408 hasConcept C2778093883 @default.
- W2000473408 hasConcept C2779177272 @default.
- W2000473408 hasConcept C2779279991 @default.
- W2000473408 hasConcept C2779908668 @default.
- W2000473408 hasConcept C2781161787 @default.
- W2000473408 hasConcept C513476851 @default.
- W2000473408 hasConcept C71924100 @default.
- W2000473408 hasConceptScore W2000473408C126322002 @default.
- W2000473408 hasConceptScore W2000473408C134018914 @default.
- W2000473408 hasConceptScore W2000473408C142724271 @default.
- W2000473408 hasConceptScore W2000473408C24998067 @default.
- W2000473408 hasConceptScore W2000473408C2775871022 @default.
- W2000473408 hasConceptScore W2000473408C2777812360 @default.
- W2000473408 hasConceptScore W2000473408C2777843972 @default.
- W2000473408 hasConceptScore W2000473408C2778093883 @default.
- W2000473408 hasConceptScore W2000473408C2779177272 @default.
- W2000473408 hasConceptScore W2000473408C2779279991 @default.
- W2000473408 hasConceptScore W2000473408C2779908668 @default.
- W2000473408 hasConceptScore W2000473408C2781161787 @default.
- W2000473408 hasConceptScore W2000473408C513476851 @default.
- W2000473408 hasConceptScore W2000473408C71924100 @default.
- W2000473408 hasIssue "6" @default.
- W2000473408 hasLocation W20004734081 @default.
- W2000473408 hasOpenAccess W2000473408 @default.
- W2000473408 hasPrimaryLocation W20004734081 @default.
- W2000473408 hasRelatedWork W136258974 @default.
- W2000473408 hasRelatedWork W1898241623 @default.
- W2000473408 hasRelatedWork W1994717858 @default.
- W2000473408 hasRelatedWork W2028783233 @default.
- W2000473408 hasRelatedWork W2072396112 @default.
- W2000473408 hasRelatedWork W2171466849 @default.