Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000479836> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2000479836 abstract "Abstract Background: Although the new anti-influenza drugs are licensed for therapeutic use, it is anticipated that they will also play a role in prophylaxis in combination with vaccine. It is thus imperative to know the minimal time necessary for antiviral prophylaxis before a vaccine-induced protective immune response can be anticipated. Methods: We have conducted a double blind placebo controlled trial with 40 young healthy volunteers (18 males, 22 females; age range 21–32 years old) who were vaccinated intramuscularly with licensed split virus vaccine and received 20-mg Relenza (24 subjects) or placebo (16 subjects) daily for a period of 14 days. Heparinised blood was collected prevaccination and up to 42 days postvaccination and analysed using the ELISPOT and HI assays. Results: No significant differences were observed in the magnitude or time course of the antibody response between the Relenza and placebo groups for the influenza A/H3N2 and B strains. However, the placebo group responded better to the A/H1N1 strain than the Relenza group at 7 and 9 days postvaccination. Conclusions: Relenza treatment was necessary for a minimum of 1 week and by day 12 the majority of volunteers (>80%) had a protective HI titre to all three strains." @default.
- W2000479836 created "2016-06-24" @default.
- W2000479836 creator A5025723659 @default.
- W2000479836 creator A5065036784 @default.
- W2000479836 creator A5070435067 @default.
- W2000479836 creator A5073654506 @default.
- W2000479836 date "2001-10-01" @default.
- W2000479836 modified "2023-09-23" @default.
- W2000479836 title "The effect of Relenza treatment on the early immune response induced after influenza vaccination" @default.
- W2000479836 cites W1965670194 @default.
- W2000479836 cites W1967938917 @default.
- W2000479836 cites W1981513529 @default.
- W2000479836 cites W1994200209 @default.
- W2000479836 cites W1999181335 @default.
- W2000479836 cites W2039333054 @default.
- W2000479836 cites W2046339130 @default.
- W2000479836 cites W2093334593 @default.
- W2000479836 cites W2107587363 @default.
- W2000479836 doi "https://doi.org/10.1016/s0531-5131(01)00372-7" @default.
- W2000479836 hasPublicationYear "2001" @default.
- W2000479836 type Work @default.
- W2000479836 sameAs 2000479836 @default.
- W2000479836 citedByCount "1" @default.
- W2000479836 crossrefType "journal-article" @default.
- W2000479836 hasAuthorship W2000479836A5025723659 @default.
- W2000479836 hasAuthorship W2000479836A5065036784 @default.
- W2000479836 hasAuthorship W2000479836A5070435067 @default.
- W2000479836 hasAuthorship W2000479836A5073654506 @default.
- W2000479836 hasConcept C126322002 @default.
- W2000479836 hasConcept C142724271 @default.
- W2000479836 hasConcept C159047783 @default.
- W2000479836 hasConcept C203014093 @default.
- W2000479836 hasConcept C204787440 @default.
- W2000479836 hasConcept C22070199 @default.
- W2000479836 hasConcept C2522874641 @default.
- W2000479836 hasConcept C27081682 @default.
- W2000479836 hasConcept C2776090121 @default.
- W2000479836 hasConcept C2779053233 @default.
- W2000479836 hasConcept C2780689484 @default.
- W2000479836 hasConcept C3018913218 @default.
- W2000479836 hasConcept C32611913 @default.
- W2000479836 hasConcept C71924100 @default.
- W2000479836 hasConcept C8891405 @default.
- W2000479836 hasConceptScore W2000479836C126322002 @default.
- W2000479836 hasConceptScore W2000479836C142724271 @default.
- W2000479836 hasConceptScore W2000479836C159047783 @default.
- W2000479836 hasConceptScore W2000479836C203014093 @default.
- W2000479836 hasConceptScore W2000479836C204787440 @default.
- W2000479836 hasConceptScore W2000479836C22070199 @default.
- W2000479836 hasConceptScore W2000479836C2522874641 @default.
- W2000479836 hasConceptScore W2000479836C27081682 @default.
- W2000479836 hasConceptScore W2000479836C2776090121 @default.
- W2000479836 hasConceptScore W2000479836C2779053233 @default.
- W2000479836 hasConceptScore W2000479836C2780689484 @default.
- W2000479836 hasConceptScore W2000479836C3018913218 @default.
- W2000479836 hasConceptScore W2000479836C32611913 @default.
- W2000479836 hasConceptScore W2000479836C71924100 @default.
- W2000479836 hasConceptScore W2000479836C8891405 @default.
- W2000479836 hasLocation W20004798361 @default.
- W2000479836 hasOpenAccess W2000479836 @default.
- W2000479836 hasPrimaryLocation W20004798361 @default.
- W2000479836 hasRelatedWork W1506599976 @default.
- W2000479836 hasRelatedWork W1895663386 @default.
- W2000479836 hasRelatedWork W1964106960 @default.
- W2000479836 hasRelatedWork W1979407285 @default.
- W2000479836 hasRelatedWork W2028916472 @default.
- W2000479836 hasRelatedWork W2040237502 @default.
- W2000479836 hasRelatedWork W2055604607 @default.
- W2000479836 hasRelatedWork W2087839484 @default.
- W2000479836 hasRelatedWork W2106733283 @default.
- W2000479836 hasRelatedWork W2109139145 @default.
- W2000479836 hasRelatedWork W2135115769 @default.
- W2000479836 hasRelatedWork W2158991840 @default.
- W2000479836 hasRelatedWork W2164574152 @default.
- W2000479836 hasRelatedWork W2192165606 @default.
- W2000479836 hasRelatedWork W2320043420 @default.
- W2000479836 hasRelatedWork W2320380017 @default.
- W2000479836 hasRelatedWork W2423096141 @default.
- W2000479836 hasRelatedWork W2462814793 @default.
- W2000479836 hasRelatedWork W2615607585 @default.
- W2000479836 hasRelatedWork W2749720702 @default.
- W2000479836 isParatext "false" @default.
- W2000479836 isRetracted "false" @default.
- W2000479836 magId "2000479836" @default.
- W2000479836 workType "article" @default.