Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000481471> ?p ?o ?g. }
- W2000481471 endingPage "4514" @default.
- W2000481471 startingPage "4505" @default.
- W2000481471 abstract "During catalysis, the heme in nitric oxide synthase (NOS) binds NO before releasing it to the environment. Oxidation of the NOS ferrous heme-NO complex by O2 is key for catalytic cycling, but the mechanism is unclear. We utilized stopped-flow methods to study the reaction of O2 with ferrous heme-NO complexes of inducible and neuronal NOS enzymes. We found that the reaction does not involve heme-NO dissociation, but instead proceeds by a rapid direct reaction of O2 with the ferrous heme-NO complex. This behavior is novel and may distinguish heme-thiolate enzymes, such as NOS, from related heme proteins." @default.
- W2000481471 created "2016-06-24" @default.
- W2000481471 creator A5017139036 @default.
- W2000481471 creator A5034820453 @default.
- W2000481471 creator A5067430639 @default.
- W2000481471 date "2009-07-27" @default.
- W2000481471 modified "2023-09-30" @default.
- W2000481471 title "Fast ferrous heme-NO oxidation in nitric oxide synthases" @default.
- W2000481471 cites W1487443561 @default.
- W2000481471 cites W1541963905 @default.
- W2000481471 cites W1545912435 @default.
- W2000481471 cites W1652764779 @default.
- W2000481471 cites W1965295255 @default.
- W2000481471 cites W1969600052 @default.
- W2000481471 cites W1971902632 @default.
- W2000481471 cites W1980805550 @default.
- W2000481471 cites W1983861507 @default.
- W2000481471 cites W1985103276 @default.
- W2000481471 cites W1986398709 @default.
- W2000481471 cites W1987756044 @default.
- W2000481471 cites W1990768518 @default.
- W2000481471 cites W1992392409 @default.
- W2000481471 cites W1997030028 @default.
- W2000481471 cites W2005819238 @default.
- W2000481471 cites W2015242997 @default.
- W2000481471 cites W2018328725 @default.
- W2000481471 cites W2024060265 @default.
- W2000481471 cites W2026623916 @default.
- W2000481471 cites W2030076441 @default.
- W2000481471 cites W2035187178 @default.
- W2000481471 cites W2040325440 @default.
- W2000481471 cites W2041283753 @default.
- W2000481471 cites W2042057179 @default.
- W2000481471 cites W2043210684 @default.
- W2000481471 cites W2043392317 @default.
- W2000481471 cites W2043606464 @default.
- W2000481471 cites W2044259132 @default.
- W2000481471 cites W2045814548 @default.
- W2000481471 cites W2054193987 @default.
- W2000481471 cites W2056420994 @default.
- W2000481471 cites W2068288884 @default.
- W2000481471 cites W2069848230 @default.
- W2000481471 cites W2073879336 @default.
- W2000481471 cites W2074726300 @default.
- W2000481471 cites W2076687382 @default.
- W2000481471 cites W2081078817 @default.
- W2000481471 cites W2082979623 @default.
- W2000481471 cites W2082996074 @default.
- W2000481471 cites W2083579767 @default.
- W2000481471 cites W2085805158 @default.
- W2000481471 cites W2088159558 @default.
- W2000481471 cites W2096703116 @default.
- W2000481471 cites W2111308105 @default.
- W2000481471 cites W2126928545 @default.
- W2000481471 cites W2127475487 @default.
- W2000481471 cites W2130057058 @default.
- W2000481471 cites W2133709520 @default.
- W2000481471 cites W2148951514 @default.
- W2000481471 cites W2151339067 @default.
- W2000481471 cites W2168467184 @default.
- W2000481471 cites W2168686052 @default.
- W2000481471 cites W2169917527 @default.
- W2000481471 cites W4234401654 @default.
- W2000481471 cites W4237968193 @default.
- W2000481471 doi "https://doi.org/10.1111/j.1742-4658.2009.07157.x" @default.
- W2000481471 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2737443" @default.
- W2000481471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19691141" @default.
- W2000481471 hasPublicationYear "2009" @default.
- W2000481471 type Work @default.
- W2000481471 sameAs 2000481471 @default.
- W2000481471 citedByCount "26" @default.
- W2000481471 countsByYear W20004814712012 @default.
- W2000481471 countsByYear W20004814712013 @default.
- W2000481471 countsByYear W20004814712014 @default.
- W2000481471 countsByYear W20004814712015 @default.
- W2000481471 countsByYear W20004814712016 @default.
- W2000481471 countsByYear W20004814712018 @default.
- W2000481471 countsByYear W20004814712019 @default.
- W2000481471 countsByYear W20004814712020 @default.
- W2000481471 countsByYear W20004814712021 @default.
- W2000481471 countsByYear W20004814712022 @default.
- W2000481471 countsByYear W20004814712023 @default.
- W2000481471 crossrefType "journal-article" @default.
- W2000481471 hasAuthorship W2000481471A5017139036 @default.
- W2000481471 hasAuthorship W2000481471A5034820453 @default.
- W2000481471 hasAuthorship W2000481471A5067430639 @default.
- W2000481471 hasBestOaLocation W20004814711 @default.
- W2000481471 hasConcept C161790260 @default.
- W2000481471 hasConcept C178790620 @default.
- W2000481471 hasConcept C181199279 @default.
- W2000481471 hasConcept C185592680 @default.
- W2000481471 hasConcept C197957613 @default.
- W2000481471 hasConcept C20705724 @default.
- W2000481471 hasConcept C2775832776 @default.
- W2000481471 hasConcept C2776217839 @default.
- W2000481471 hasConcept C2777622882 @default.
- W2000481471 hasConcept C519581460 @default.
- W2000481471 hasConcept C55493867 @default.