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• W2000485781 abstract "Primary central nervous system non-Hodgkin lymphoma (PCNSL) is a malignant lymphoma limited to the cranial-spinal axis in the absence of systemic lymphoma. Historically, PCNSL accounts for fewer than 5% of all cases of primary intracranial neoplasms. PCNSL is rare in immunocompetent young adults. Although the prognosis for PCNSL is poor, approximately 20%–30% percent of cases achieve a cure. We report two cases of PCNSL originating in the ventricle in otherwise healthy immunocompetent young adults. A 27-year-old man presented with 10 days of nausea, vomiting, and headache and was found to have a large intraventricular mass emanating from the choroid plexus with resultant hydrocephalus. He underwent placement of external ventricular drain and systemic and intrathecal chemotherapy for cytologically proven PCNSL. A 31-year-old pregnant woman presented with headaches, vision difficulties, and ataxia and was found to have a septum pellucidum mass. She underwent craniotomy and subtotal resection of the mass with subsequent systemic therapy and whole brain radiation for treatment of PCNSL. To our knowledge, this is the first report of primary CNS lymphoma of the choroid plexus and septum pellucidum in otherwise healthy, immunocompetent young adults." @default.
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• W2000485781 date "2013-03-01" @default.
• W2000485781 modified "2023-09-24" @default.
• W2000485781 title "Atypical Presentation of Primary Central Nervous System Non-Hodgkin Lymphoma in Immunocompetent Young Adults" @default.
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• W2000485781 doi "https://doi.org/10.1016/j.wneu.2012.07.026" @default.
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