FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000485976> ?p ?o ?g. }

• W2000485976 endingPage "351" @default.
• W2000485976 startingPage "335" @default.
• W2000485976 abstract "Bacterial wound infection is a major problem, which hinders the normal healing process. In this study, a collagen bilayer dressing with ciprofloxacin was prepared from succinylated type-I collagen; FT-IR spectroscopy, SEM analysis, in vitro drug release pattern, antimicrobial activity and in vivo efficacy of the dressing were studied. The healing pattern was analyzed on days 3, 5, 7, 14 and 21 by wound healing rate, bacterial population, biochemical and histological examinations of tissue samples. FT-IR spectra showed the succinylation of collagen and ionic binding of ciprofloxacin to succinylated collagen. SEM analysis showed uniform drug distribution in collagen sponge and in vitro drug release pattern showed a release profile for 3 days with effective drug concentration confirmed by zone of inhibition. Ciprofloxacin counter-acted the effect of invading bacteria, as could be seen by considerable reduction in total bacterial population of the wound. In vivo analysis showed significant wound closure, biochemical analysis, such as protein, DNA, hydroxyproline, SOD, catalase, hexosamine and uronic acid from the granulation tissue, showed enhanced healing in the group treated with collagen bilayer dressing with ciprofloxacin. Histological analysis and wound closure further confirmed proper healing. Our results suggest that sustained release of ciprofloxacin from a collagen bilayer dressing eliminates bacteria at the site of infection, leaving a pathogen-free wound environment, and it can be used as a dressing for an on-site delivery system." @default.
• W2000485976 created "2016-06-24" @default.
• W2000485976 creator A5013270808 @default.
• W2000485976 creator A5067664888 @default.
• W2000485976 creator A5068415169 @default.
• W2000485976 creator A5088291280 @default.
• W2000485976 date "2007-01-01" @default.
• W2000485976 modified "2023-09-30" @default.
• W2000485976 title "Collagen bilayer dressing with ciprofloxacin, an effective system for infected wound healing" @default.
• W2000485976 cites W1567088540 @default.
• W2000485976 cites W1750690213 @default.
• W2000485976 cites W1775749144 @default.
• W2000485976 cites W1968286480 @default.
• W2000485976 cites W1969612347 @default.
• W2000485976 cites W1972229031 @default.
• W2000485976 cites W1975204088 @default.
• W2000485976 cites W1977779461 @default.
• W2000485976 cites W1990166357 @default.
• W2000485976 cites W1997142624 @default.
• W2000485976 cites W1999652145 @default.
• W2000485976 cites W2010191874 @default.
• W2000485976 cites W2010513003 @default.
• W2000485976 cites W2020509336 @default.
• W2000485976 cites W2032460851 @default.
• W2000485976 cites W2033625039 @default.
• W2000485976 cites W2039601624 @default.
• W2000485976 cites W2040964323 @default.
• W2000485976 cites W2058560666 @default.
• W2000485976 cites W2068911309 @default.
• W2000485976 cites W2070760666 @default.
• W2000485976 cites W2077953225 @default.
• W2000485976 cites W2079021034 @default.
• W2000485976 cites W2079209512 @default.
• W2000485976 cites W2088964673 @default.
• W2000485976 cites W2100368139 @default.
• W2000485976 cites W2118471200 @default.
• W2000485976 cites W2121052722 @default.
• W2000485976 cites W2129925845 @default.
• W2000485976 cites W2145874740 @default.
• W2000485976 cites W2161812036 @default.
• W2000485976 doi "https://doi.org/10.1163/156856207779996913" @default.
• W2000485976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17471769" @default.
• W2000485976 hasPublicationYear "2007" @default.
• W2000485976 type Work @default.
• W2000485976 sameAs 2000485976 @default.
• W2000485976 citedByCount "38" @default.
• W2000485976 countsByYear W20004859762012 @default.
• W2000485976 countsByYear W20004859762013 @default.
• W2000485976 countsByYear W20004859762014 @default.
• W2000485976 countsByYear W20004859762015 @default.
• W2000485976 countsByYear W20004859762016 @default.
• W2000485976 countsByYear W20004859762017 @default.
• W2000485976 countsByYear W20004859762018 @default.
• W2000485976 countsByYear W20004859762019 @default.
• W2000485976 countsByYear W20004859762020 @default.
• W2000485976 countsByYear W20004859762021 @default.
• W2000485976 countsByYear W20004859762022 @default.
• W2000485976 countsByYear W20004859762023 @default.
• W2000485976 crossrefType "journal-article" @default.
• W2000485976 hasAuthorship W2000485976A5013270808 @default.
• W2000485976 hasAuthorship W2000485976A5067664888 @default.
• W2000485976 hasAuthorship W2000485976A5068415169 @default.
• W2000485976 hasAuthorship W2000485976A5088291280 @default.
• W2000485976 hasConcept C141071460 @default.
• W2000485976 hasConcept C150903083 @default.
• W2000485976 hasConcept C185592680 @default.
• W2000485976 hasConcept C207001950 @default.
• W2000485976 hasConcept C2776055305 @default.
• W2000485976 hasConcept C2778512257 @default.
• W2000485976 hasConcept C2779797417 @default.
• W2000485976 hasConcept C2780269544 @default.
• W2000485976 hasConcept C2908647359 @default.
• W2000485976 hasConcept C501593827 @default.
• W2000485976 hasConcept C55493867 @default.
• W2000485976 hasConcept C71924100 @default.
• W2000485976 hasConcept C86803240 @default.
• W2000485976 hasConcept C89423630 @default.
• W2000485976 hasConcept C98274493 @default.
• W2000485976 hasConcept C99454951 @default.
• W2000485976 hasConceptScore W2000485976C141071460 @default.
• W2000485976 hasConceptScore W2000485976C150903083 @default.
• W2000485976 hasConceptScore W2000485976C185592680 @default.
• W2000485976 hasConceptScore W2000485976C207001950 @default.
• W2000485976 hasConceptScore W2000485976C2776055305 @default.
• W2000485976 hasConceptScore W2000485976C2778512257 @default.
• W2000485976 hasConceptScore W2000485976C2779797417 @default.
• W2000485976 hasConceptScore W2000485976C2780269544 @default.
• W2000485976 hasConceptScore W2000485976C2908647359 @default.
• W2000485976 hasConceptScore W2000485976C501593827 @default.
• W2000485976 hasConceptScore W2000485976C55493867 @default.
• W2000485976 hasConceptScore W2000485976C71924100 @default.
• W2000485976 hasConceptScore W2000485976C86803240 @default.
• W2000485976 hasConceptScore W2000485976C89423630 @default.
• W2000485976 hasConceptScore W2000485976C98274493 @default.
• W2000485976 hasConceptScore W2000485976C99454951 @default.
• W2000485976 hasIssue "3" @default.
• W2000485976 hasLocation W20004859761 @default.
• W2000485976 hasLocation W20004859762 @default.

• next