FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000490237> ?p ?o ?g. }

• W2000490237 endingPage "42" @default.
• W2000490237 startingPage "27" @default.
• W2000490237 abstract "In the body, osteocytes reside in lacunae, lenticular shaped cavities within mineralized bone. These cells are linked to each other and surface-residing osteoblasts via physical channels known as gap junctions. It has been suggested that osteocytes sense mechanical load applied to bone and relay that signal to osteoclasts and osteoblasts. Current in vitro and in vivo models of mechanotransduction face temporal and spatial barriers. Recent advances in polydimethylsiloxane (PDMS) based microfabrication techniques may be able to overcome some of these hurdles. However, before the bone research field can effectively utilize microsystems techniques, fundamental groundwork must be completed. This study characterized the behaviour of osteocytes on PDMS coated with collagen type I (CTI) and provides the framework for bone cell mechanotransduction studies using microsystems. The goal was to determine whether osteocytes were adversely affected by the substrate material by comparing their behaviour to a standard glass substrate. In addition, optimal culture conditions and time points for growing osteocytes on PDMS substrates were determined. Results of this study suggested that use of PDMS does not adversely affect osteocyte behaviour. Furthermore, the results demonstrated that osteocytes should be cultured for no less than 72 hours prior to experimentation to allow the establishment and maintenance of phenotypic characteristics. These results completed essential groundwork necessary for further studies regarding osteocytes in microsystems modelling utilizing PDMS." @default.
• W2000490237 created "2016-06-24" @default.
• W2000490237 creator A5001835851 @default.
• W2000490237 creator A5037009151 @default.
• W2000490237 creator A5045164773 @default.
• W2000490237 creator A5046439297 @default.
• W2000490237 creator A5056107094 @default.
• W2000490237 date "2012-12-01" @default.
• W2000490237 modified "2023-09-23" @default.
• W2000490237 title "Osteocyte Characterization on Polydimethylsiloxane Substrates for Microsystems Applications" @default.
• W2000490237 cites W1531951748 @default.
• W2000490237 cites W1996161852 @default.
• W2000490237 cites W2007478852 @default.
• W2000490237 cites W2014684811 @default.
• W2000490237 cites W2019717438 @default.
• W2000490237 cites W2025096038 @default.
• W2000490237 cites W2043991983 @default.
• W2000490237 cites W2044930326 @default.
• W2000490237 cites W2056937003 @default.
• W2000490237 cites W2066906765 @default.
• W2000490237 cites W2068535611 @default.
• W2000490237 cites W2078883007 @default.
• W2000490237 cites W2080458769 @default.
• W2000490237 cites W2087560312 @default.
• W2000490237 cites W2091514824 @default.
• W2000490237 cites W2130809244 @default.
• W2000490237 cites W2157383773 @default.
• W2000490237 cites W2167572811 @default.
• W2000490237 cites W2345043532 @default.
• W2000490237 cites W28112311 @default.
• W2000490237 doi "https://doi.org/10.4028/www.scientific.net/jbbte.16.27" @default.
• W2000490237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6150457" @default.
• W2000490237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30245613" @default.
• W2000490237 hasPublicationYear "2012" @default.
• W2000490237 type Work @default.
• W2000490237 sameAs 2000490237 @default.
• W2000490237 citedByCount "7" @default.
• W2000490237 countsByYear W20004902372014 @default.
• W2000490237 countsByYear W20004902372015 @default.
• W2000490237 countsByYear W20004902372016 @default.
• W2000490237 countsByYear W20004902372018 @default.
• W2000490237 countsByYear W20004902372020 @default.
• W2000490237 countsByYear W20004902372022 @default.
• W2000490237 crossrefType "journal-article" @default.
• W2000490237 hasAuthorship W2000490237A5001835851 @default.
• W2000490237 hasAuthorship W2000490237A5037009151 @default.
• W2000490237 hasAuthorship W2000490237A5045164773 @default.
• W2000490237 hasAuthorship W2000490237A5046439297 @default.
• W2000490237 hasAuthorship W2000490237A5056107094 @default.
• W2000490237 hasBestOaLocation W20004902372 @default.
• W2000490237 hasConcept C127413603 @default.
• W2000490237 hasConcept C136229726 @default.
• W2000490237 hasConcept C136525101 @default.
• W2000490237 hasConcept C142724271 @default.
• W2000490237 hasConcept C151054161 @default.
• W2000490237 hasConcept C171250308 @default.
• W2000490237 hasConcept C181104049 @default.
• W2000490237 hasConcept C185592680 @default.
• W2000490237 hasConcept C18903297 @default.
• W2000490237 hasConcept C192562407 @default.
• W2000490237 hasConcept C202751555 @default.
• W2000490237 hasConcept C204787440 @default.
• W2000490237 hasConcept C2777289219 @default.
• W2000490237 hasConcept C2778260815 @default.
• W2000490237 hasConcept C2779849746 @default.
• W2000490237 hasConcept C2780973866 @default.
• W2000490237 hasConcept C527607 @default.
• W2000490237 hasConcept C55493867 @default.
• W2000490237 hasConcept C71924100 @default.
• W2000490237 hasConcept C86803240 @default.
• W2000490237 hasConcept C95444343 @default.
• W2000490237 hasConceptScore W2000490237C127413603 @default.
• W2000490237 hasConceptScore W2000490237C136229726 @default.
• W2000490237 hasConceptScore W2000490237C136525101 @default.
• W2000490237 hasConceptScore W2000490237C142724271 @default.
• W2000490237 hasConceptScore W2000490237C151054161 @default.
• W2000490237 hasConceptScore W2000490237C171250308 @default.
• W2000490237 hasConceptScore W2000490237C181104049 @default.
• W2000490237 hasConceptScore W2000490237C185592680 @default.
• W2000490237 hasConceptScore W2000490237C18903297 @default.
• W2000490237 hasConceptScore W2000490237C192562407 @default.
• W2000490237 hasConceptScore W2000490237C202751555 @default.
• W2000490237 hasConceptScore W2000490237C204787440 @default.
• W2000490237 hasConceptScore W2000490237C2777289219 @default.
• W2000490237 hasConceptScore W2000490237C2778260815 @default.
• W2000490237 hasConceptScore W2000490237C2779849746 @default.
• W2000490237 hasConceptScore W2000490237C2780973866 @default.
• W2000490237 hasConceptScore W2000490237C527607 @default.
• W2000490237 hasConceptScore W2000490237C55493867 @default.
• W2000490237 hasConceptScore W2000490237C71924100 @default.
• W2000490237 hasConceptScore W2000490237C86803240 @default.
• W2000490237 hasConceptScore W2000490237C95444343 @default.
• W2000490237 hasLocation W20004902371 @default.
• W2000490237 hasLocation W20004902372 @default.
• W2000490237 hasLocation W20004902373 @default.
• W2000490237 hasLocation W20004902374 @default.
• W2000490237 hasOpenAccess W2000490237 @default.
• W2000490237 hasPrimaryLocation W20004902371 @default.

• next