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- W2000491201 abstract "This study sought to establish a pharmacological profile for N-095, a crude drug containing red ginseng, polygala root, saffron, antelope horn and aloe wood. Our studies on rats and mice revealed a number of pharmacological properties of this novel drug. N-095 increased the forced swimming time in mice and prevented gastric ulcers in rats under restraint and water immersion stress conditions at 100 mg/kg or higher. It also prevented footpad swelling in rats treated with λ-carrageenin and histamine-induced gastric ulcers in rats at 300 mg/kg or higher. Furthermore, N-095 augmented the sedative effect in mice induced by hexobarbital, which is characterized by a decreased spontaneous motor activity and a prolongation of sleeping time. N-095 also stimulated spontaneous contractility of the uterus in rats at 1000 mg/kg and 2000 mg/kg and prevented hemolysis of erythrocytes by heating. In contrast, N-095 had no effect on the respiratory or cardiovascular system or on water and electrolyte regulation in rats or mice. These results show that N-095 is a relatively safe drug for use as a nutrient or tonic." @default.
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- W2000491201 date "2005-01-01" @default.
- W2000491201 modified "2023-09-25" @default.
- W2000491201 title "Pharmacological Properties of N-095, a Drug Containing Red Ginseng, Polygala Root, Saffron, Antelope Horn and Aloe Wood" @default.
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- W2000491201 doi "https://doi.org/10.1142/s0192415x05002655" @default.
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