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• W2000493516 abstract "ObjectiveTo determine whether the presence of a single umbilical artery is associated with intrauterine growth restriction (IUGR), intrauterine fetal demise (IUFD), or major congenital anomalies.Study DesignWe performed a retrospective cohort study of all consecutive singleton pregnancies undergoing routine anatomic survey between 1990 and 2007 at a major tertiary medical center. Two dedicated research nurses obtained complete pregnancy outcome data in an on-going manner. Pregnancies with a diagnosis of single umbilical artery (SUA) were compared to those with two umbilical arteries. The primary outcomes of interest were IUGR (<10th percentile), IUFD (>20 weeks gestation), and major congenital anomalies. Multivariable logistic regression was used to refine the risk association between SUA and adverse pregnancy outcomes while adjusting for confounding effects.ResultsConclusionOur data suggest an increased risk of IUGR and IUFD when the diagnosis of SUA is made, making a clinical recommendation for serial growth assessments and non-stress testing in the setting of SUA reasonable. ObjectiveTo determine whether the presence of a single umbilical artery is associated with intrauterine growth restriction (IUGR), intrauterine fetal demise (IUFD), or major congenital anomalies. To determine whether the presence of a single umbilical artery is associated with intrauterine growth restriction (IUGR), intrauterine fetal demise (IUFD), or major congenital anomalies. Study DesignWe performed a retrospective cohort study of all consecutive singleton pregnancies undergoing routine anatomic survey between 1990 and 2007 at a major tertiary medical center. Two dedicated research nurses obtained complete pregnancy outcome data in an on-going manner. Pregnancies with a diagnosis of single umbilical artery (SUA) were compared to those with two umbilical arteries. The primary outcomes of interest were IUGR (<10th percentile), IUFD (>20 weeks gestation), and major congenital anomalies. Multivariable logistic regression was used to refine the risk association between SUA and adverse pregnancy outcomes while adjusting for confounding effects. We performed a retrospective cohort study of all consecutive singleton pregnancies undergoing routine anatomic survey between 1990 and 2007 at a major tertiary medical center. Two dedicated research nurses obtained complete pregnancy outcome data in an on-going manner. Pregnancies with a diagnosis of single umbilical artery (SUA) were compared to those with two umbilical arteries. The primary outcomes of interest were IUGR (<10th percentile), IUFD (>20 weeks gestation), and major congenital anomalies. Multivariable logistic regression was used to refine the risk association between SUA and adverse pregnancy outcomes while adjusting for confounding effects. Results ConclusionOur data suggest an increased risk of IUGR and IUFD when the diagnosis of SUA is made, making a clinical recommendation for serial growth assessments and non-stress testing in the setting of SUA reasonable. Our data suggest an increased risk of IUGR and IUFD when the diagnosis of SUA is made, making a clinical recommendation for serial growth assessments and non-stress testing in the setting of SUA reasonable." @default.
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• W2000493516 date "2009-12-01" @default.
• W2000493516 modified "2023-09-23" @default.
• W2000493516 title "104: Single umbilical artery: much ado about nothing?" @default.
• W2000493516 doi "https://doi.org/10.1016/j.ajog.2009.10.119" @default.
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