FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000494140> ?p ?o ?g. }

• W2000494140 endingPage "7" @default.
• W2000494140 startingPage "1" @default.
• W2000494140 abstract "Ingestion of energy rich high fat diets is one of the determining factors associated with the obesity epidemic. Therefore, much can be learned from studies of obesity-related substances given to animals fed a high fat diet. The progesterone metabolite allopregnanolone is a potent positive modulator of the gamma-aminobutyric acid (GABA)A-receptor, and both allopregnanolone and GABA have been implicated in evoking hyperphagia. In this study, food intake and body weight gain were investigated during repeated allopregnanolone exposure. Male Wistar rats were studied when fed chow ad libitum, with chow access for 4h per day or with 45% high fat pellets for 4h per day. Rats on the high fat diet were separated into obesity prone and obesity resistant individuals. Subcutaneous injections of allopregnanolone were given once daily over five consecutive days. Repeated exposure to allopregnanolone lead to increased weight gain, significantly so in schedule fed rats on a high fat diet. The increased weight gain was correlated to an increased energy intake. Both obesity resistant and obesity prone rats responded to allopregnanolone with increased weight gain. Obesity resistant rats treated with allopregnanolone increased their energy intake and ate as much as vehicle treated obesity prone rats. Their weight gain was also increased to the level of obesity prone rats injected with just the vehicle carrier oil. Thus, it appears that allopregnanolone may be one of the endogenous factors involved in weight gain, especially when the diet is rich in fat." @default.
• W2000494140 created "2016-06-24" @default.
• W2000494140 creator A5046989158 @default.
• W2000494140 creator A5049397927 @default.
• W2000494140 creator A5053480244 @default.
• W2000494140 creator A5054798161 @default.
• W2000494140 creator A5075496894 @default.
• W2000494140 date "2015-03-01" @default.
• W2000494140 modified "2023-10-18" @default.
• W2000494140 title "Repeated allopregnanolone exposure induces weight gain in schedule fed rats on high fat diet" @default.
• W2000494140 cites W1868738362 @default.
• W2000494140 cites W1967097067 @default.
• W2000494140 cites W1972515921 @default.
• W2000494140 cites W1974748230 @default.
• W2000494140 cites W1988819654 @default.
• W2000494140 cites W1993440020 @default.
• W2000494140 cites W1998521555 @default.
• W2000494140 cites W1998882791 @default.
• W2000494140 cites W2005825980 @default.
• W2000494140 cites W2016533446 @default.
• W2000494140 cites W2024344189 @default.
• W2000494140 cites W2025114171 @default.
• W2000494140 cites W2026320973 @default.
• W2000494140 cites W2032286299 @default.
• W2000494140 cites W2032668395 @default.
• W2000494140 cites W2035915555 @default.
• W2000494140 cites W2037046144 @default.
• W2000494140 cites W2039274241 @default.
• W2000494140 cites W2043231896 @default.
• W2000494140 cites W2045924832 @default.
• W2000494140 cites W2048269355 @default.
• W2000494140 cites W2061510535 @default.
• W2000494140 cites W2063301591 @default.
• W2000494140 cites W2077369497 @default.
• W2000494140 cites W2082296856 @default.
• W2000494140 cites W2083447043 @default.
• W2000494140 cites W2089056970 @default.
• W2000494140 cites W2098865421 @default.
• W2000494140 cites W2101940795 @default.
• W2000494140 cites W2112202133 @default.
• W2000494140 cites W2123897274 @default.
• W2000494140 cites W2132858654 @default.
• W2000494140 cites W2140414617 @default.
• W2000494140 cites W2141335672 @default.
• W2000494140 doi "https://doi.org/10.1016/j.physbeh.2014.12.012" @default.
• W2000494140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25484355" @default.
• W2000494140 hasPublicationYear "2015" @default.
• W2000494140 type Work @default.
• W2000494140 sameAs 2000494140 @default.
• W2000494140 citedByCount "8" @default.
• W2000494140 countsByYear W20004941402016 @default.
• W2000494140 countsByYear W20004941402017 @default.
• W2000494140 countsByYear W20004941402018 @default.
• W2000494140 countsByYear W20004941402019 @default.
• W2000494140 countsByYear W20004941402021 @default.
• W2000494140 crossrefType "journal-article" @default.
• W2000494140 hasAuthorship W2000494140A5046989158 @default.
• W2000494140 hasAuthorship W2000494140A5049397927 @default.
• W2000494140 hasAuthorship W2000494140A5053480244 @default.
• W2000494140 hasAuthorship W2000494140A5054798161 @default.
• W2000494140 hasAuthorship W2000494140A5075496894 @default.
• W2000494140 hasConcept C126322002 @default.
• W2000494140 hasConcept C134018914 @default.
• W2000494140 hasConcept C147583825 @default.
• W2000494140 hasConcept C168258287 @default.
• W2000494140 hasConcept C170493617 @default.
• W2000494140 hasConcept C185592680 @default.
• W2000494140 hasConcept C2777477808 @default.
• W2000494140 hasConcept C2778338918 @default.
• W2000494140 hasConcept C2780320433 @default.
• W2000494140 hasConcept C44796713 @default.
• W2000494140 hasConcept C511355011 @default.
• W2000494140 hasConcept C71924100 @default.
• W2000494140 hasConceptScore W2000494140C126322002 @default.
• W2000494140 hasConceptScore W2000494140C134018914 @default.
• W2000494140 hasConceptScore W2000494140C147583825 @default.
• W2000494140 hasConceptScore W2000494140C168258287 @default.
• W2000494140 hasConceptScore W2000494140C170493617 @default.
• W2000494140 hasConceptScore W2000494140C185592680 @default.
• W2000494140 hasConceptScore W2000494140C2777477808 @default.
• W2000494140 hasConceptScore W2000494140C2778338918 @default.
• W2000494140 hasConceptScore W2000494140C2780320433 @default.
• W2000494140 hasConceptScore W2000494140C44796713 @default.
• W2000494140 hasConceptScore W2000494140C511355011 @default.
• W2000494140 hasConceptScore W2000494140C71924100 @default.
• W2000494140 hasFunder F4320321615 @default.
• W2000494140 hasFunder F4320322581 @default.
• W2000494140 hasLocation W20004941401 @default.
• W2000494140 hasLocation W20004941402 @default.
• W2000494140 hasOpenAccess W2000494140 @default.
• W2000494140 hasPrimaryLocation W20004941401 @default.
• W2000494140 hasRelatedWork W1966504330 @default.
• W2000494140 hasRelatedWork W1979139803 @default.
• W2000494140 hasRelatedWork W1991204773 @default.
• W2000494140 hasRelatedWork W2037631372 @default.
• W2000494140 hasRelatedWork W2061766728 @default.
• W2000494140 hasRelatedWork W2110444056 @default.
• W2000494140 hasRelatedWork W2748952813 @default.

• next