FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000506742> ?p ?o ?g. }

• W2000506742 endingPage "319" @default.
• W2000506742 startingPage "313" @default.
• W2000506742 abstract "Summary The role of β ‐catenin in epithelial neoplasms has been widely studied whereas current knowledge regarding β ‐catenin gene and protein expression in bone marrow cells derived from normal haematopoiesis and clonal haematological disorders is lacking. β ‐Catenin gene expression was quantitatively investigated in bone marrow cells derived from clonal haematological disorders [acute myeloid leukaemia (AML), acute lymphoblastic leukaemia (ALL), Philadelphia chromosome‐positive chronic myeloid leukaemia (Ph + CML], Ph − myeloproliferative disorders, n = 96) compared with non‐neoplastic haematopoiesis ( n = 33) by real‐time reverse transcription polymerase chain reaction. Cellular localization of β ‐catenin protein was detected by immunocytochemistry. β ‐Catenin gene expression was significantly increased in AML compared with ALL cases ( P < 0·0001), Ph + CML ( P < 0·0001) and non‐neoplastic haematopoiesis ( P = 0·019). Immunocytochemistry revealed that, in non‐neoplastic haematopoiesis, the granulopoietic lineage as well as megakaryocytes showed membranous and cytoplasmic staining to various degrees along with unlabelled nuclei. Besides haematopoiesis, β ‐catenin prominently marked bone marrow vascularity and diverse stroma cells. β ‐Catenin gene was inversely expressed in AML and ALL with a lack of protein expression in neoplastic cells in ALL. In contrast, the other haematological disorders under study, except for Ph + CML, did not show significant alterations of overall β ‐catenin gene expression compared with normal bone marrow. These data suggest different regulatory mechanisms in the expression and function of β ‐catenin in haematopoietic cells." @default.
• W2000506742 created "2016-06-24" @default.
• W2000506742 creator A5041128181 @default.
• W2000506742 creator A5044665296 @default.
• W2000506742 creator A5064219730 @default.
• W2000506742 creator A5074150116 @default.
• W2000506742 creator A5082333440 @default.
• W2000506742 creator A5084677682 @default.
• W2000506742 date "2004-07-05" @default.
• W2000506742 modified "2023-10-16" @default.
• W2000506742 title "Aberrant expression of β-catenin discriminates acute myeloid leukaemia from acute lymphoblastic leukaemia" @default.
• W2000506742 cites W129269179 @default.
• W2000506742 cites W1500827124 @default.
• W2000506742 cites W1554815317 @default.
• W2000506742 cites W189173739 @default.
• W2000506742 cites W1967137553 @default.
• W2000506742 cites W1967921405 @default.
• W2000506742 cites W1990855183 @default.
• W2000506742 cites W1998003921 @default.
• W2000506742 cites W2002404925 @default.
• W2000506742 cites W2007215839 @default.
• W2000506742 cites W2013910675 @default.
• W2000506742 cites W2030774127 @default.
• W2000506742 cites W2041140837 @default.
• W2000506742 cites W2043129312 @default.
• W2000506742 cites W2053017193 @default.
• W2000506742 cites W2067824096 @default.
• W2000506742 cites W2072630322 @default.
• W2000506742 cites W2086149372 @default.
• W2000506742 cites W2099431941 @default.
• W2000506742 cites W2104989755 @default.
• W2000506742 cites W2107277218 @default.
• W2000506742 cites W2114329786 @default.
• W2000506742 cites W2118453722 @default.
• W2000506742 cites W2119695863 @default.
• W2000506742 cites W2127617063 @default.
• W2000506742 cites W2146167376 @default.
• W2000506742 cites W2148074532 @default.
• W2000506742 cites W2150902176 @default.
• W2000506742 cites W2166254889 @default.
• W2000506742 cites W2170950989 @default.
• W2000506742 doi "https://doi.org/10.1111/j.1365-2141.2004.05049.x" @default.
• W2000506742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15257703" @default.
• W2000506742 hasPublicationYear "2004" @default.
• W2000506742 type Work @default.
• W2000506742 sameAs 2000506742 @default.
• W2000506742 citedByCount "45" @default.
• W2000506742 countsByYear W20005067422012 @default.
• W2000506742 countsByYear W20005067422013 @default.
• W2000506742 countsByYear W20005067422014 @default.
• W2000506742 countsByYear W20005067422015 @default.
• W2000506742 countsByYear W20005067422016 @default.
• W2000506742 countsByYear W20005067422018 @default.
• W2000506742 countsByYear W20005067422019 @default.
• W2000506742 countsByYear W20005067422020 @default.
• W2000506742 countsByYear W20005067422022 @default.
• W2000506742 crossrefType "journal-article" @default.
• W2000506742 hasAuthorship W2000506742A5041128181 @default.
• W2000506742 hasAuthorship W2000506742A5044665296 @default.
• W2000506742 hasAuthorship W2000506742A5064219730 @default.
• W2000506742 hasAuthorship W2000506742A5074150116 @default.
• W2000506742 hasAuthorship W2000506742A5082333440 @default.
• W2000506742 hasAuthorship W2000506742A5084677682 @default.
• W2000506742 hasBestOaLocation W20005067421 @default.
• W2000506742 hasConcept C109159458 @default.
• W2000506742 hasConcept C142724271 @default.
• W2000506742 hasConcept C203014093 @default.
• W2000506742 hasConcept C2779282312 @default.
• W2000506742 hasConcept C2780007613 @default.
• W2000506742 hasConcept C28328180 @default.
• W2000506742 hasConcept C2910274570 @default.
• W2000506742 hasConcept C35866371 @default.
• W2000506742 hasConcept C502942594 @default.
• W2000506742 hasConcept C71924100 @default.
• W2000506742 hasConcept C86803240 @default.
• W2000506742 hasConcept C95444343 @default.
• W2000506742 hasConceptScore W2000506742C109159458 @default.
• W2000506742 hasConceptScore W2000506742C142724271 @default.
• W2000506742 hasConceptScore W2000506742C203014093 @default.
• W2000506742 hasConceptScore W2000506742C2779282312 @default.
• W2000506742 hasConceptScore W2000506742C2780007613 @default.
• W2000506742 hasConceptScore W2000506742C28328180 @default.
• W2000506742 hasConceptScore W2000506742C2910274570 @default.
• W2000506742 hasConceptScore W2000506742C35866371 @default.
• W2000506742 hasConceptScore W2000506742C502942594 @default.
• W2000506742 hasConceptScore W2000506742C71924100 @default.
• W2000506742 hasConceptScore W2000506742C86803240 @default.
• W2000506742 hasConceptScore W2000506742C95444343 @default.
• W2000506742 hasIssue "3" @default.
• W2000506742 hasLocation W20005067421 @default.
• W2000506742 hasLocation W20005067422 @default.
• W2000506742 hasOpenAccess W2000506742 @default.
• W2000506742 hasPrimaryLocation W20005067421 @default.
• W2000506742 hasRelatedWork W151652346 @default.
• W2000506742 hasRelatedWork W1973406296 @default.
• W2000506742 hasRelatedWork W1975353758 @default.
• W2000506742 hasRelatedWork W2081779518 @default.
• W2000506742 hasRelatedWork W2100140007 @default.

• next