FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000510502> ?p ?o ?g. }

• W2000510502 endingPage "442" @default.
• W2000510502 startingPage "441" @default.
• W2000510502 abstract "1.Recognize the significant morbidity and etiology of intractable hiccups, especially in the palliative care population.2.Review treatment options for intractable hiccups. Hiccups, which are usually self-limited and benign, can become intractable and be associated with significant morbidity, especially in palliative care patients. Management of intractable hiccups (IH) poses a challenge to the palliative care provider. We present a case of a patient with IH who responded to the combination of scheduled baclofen and olanzapine. Current therapies for the management of IH are also reviewed. A 45-year-old male with multiple myeloma and plasma cell leukemia, status-post autologous and allogenic bone marrow transplantation developed IH for which a palliative care consultation was requested. As oral intake was poor secondary to his hiccups, total parenteral nutrition (TPN) had been initiated. A thorough assessment revealed that the potential etiologies of his hiccups were most likely related to methylprednisolone, the malignancy itself, and recent chemotherapy. Initial treatment with oral and intravenous chlorpromazine resulted in limited improvement and significant sedation. Palliative care service recommendations included a trial of scheduled metoclopramide and later, a retrial of chlorpromazine; both plans failed. Haloperidol and atropine were tried without success and the patient declined the option of a phrenic nerve block. Baclofen 10 mg PO TID and olanzapine 7.5 mg PO QHS were started; while the baclofen provided significant relief, the patient had a remarkable response to olanzapine. Within 24 hours of the initiation of olanzapine, the patient was able to tolerate an oral diet. Three weeks later the patient was discharged to home and TPN was discontinued. IH in the palliative care patient can be debilitating and difficult to manage. Several therapies have been proposed. Pharmacologic interventions include traditional options such as chlorpromazine, haloperidol, and metoclopramide. Non-traditional choices such as baclofen and olanzapine may be also considered in the management of IH." @default.
• W2000510502 created "2016-06-24" @default.
• W2000510502 creator A5017152760 @default.
• W2000510502 creator A5063229974 @default.
• W2000510502 creator A5075201250 @default.
• W2000510502 date "2012-02-01" @default.
• W2000510502 modified "2023-10-18" @default.
• W2000510502 title "Management of Intractable Hiccups in a Patient With Multiple Myeloma and Plasma Cell Leukemia (737)" @default.
• W2000510502 doi "https://doi.org/10.1016/j.jpainsymman.2011.12.215" @default.
• W2000510502 hasPublicationYear "2012" @default.
• W2000510502 type Work @default.
• W2000510502 sameAs 2000510502 @default.
• W2000510502 citedByCount "0" @default.
• W2000510502 crossrefType "journal-article" @default.
• W2000510502 hasAuthorship W2000510502A5017152760 @default.
• W2000510502 hasAuthorship W2000510502A5063229974 @default.
• W2000510502 hasAuthorship W2000510502A5075201250 @default.
• W2000510502 hasBestOaLocation W20005105021 @default.
• W2000510502 hasConcept C118552586 @default.
• W2000510502 hasConcept C159110408 @default.
• W2000510502 hasConcept C177713679 @default.
• W2000510502 hasConcept C2776412080 @default.
• W2000510502 hasConcept C2776619155 @default.
• W2000510502 hasConcept C2778479196 @default.
• W2000510502 hasConcept C2779761075 @default.
• W2000510502 hasConcept C2780852908 @default.
• W2000510502 hasConcept C2994186709 @default.
• W2000510502 hasConcept C42219234 @default.
• W2000510502 hasConcept C71924100 @default.
• W2000510502 hasConceptScore W2000510502C118552586 @default.
• W2000510502 hasConceptScore W2000510502C159110408 @default.
• W2000510502 hasConceptScore W2000510502C177713679 @default.
• W2000510502 hasConceptScore W2000510502C2776412080 @default.
• W2000510502 hasConceptScore W2000510502C2776619155 @default.
• W2000510502 hasConceptScore W2000510502C2778479196 @default.
• W2000510502 hasConceptScore W2000510502C2779761075 @default.
• W2000510502 hasConceptScore W2000510502C2780852908 @default.
• W2000510502 hasConceptScore W2000510502C2994186709 @default.
• W2000510502 hasConceptScore W2000510502C42219234 @default.
• W2000510502 hasConceptScore W2000510502C71924100 @default.
• W2000510502 hasIssue "2" @default.
• W2000510502 hasLocation W20005105021 @default.
• W2000510502 hasOpenAccess W2000510502 @default.
• W2000510502 hasPrimaryLocation W20005105021 @default.
• W2000510502 hasRelatedWork W2007848651 @default.
• W2000510502 hasRelatedWork W2071531639 @default.
• W2000510502 hasRelatedWork W2100869784 @default.
• W2000510502 hasRelatedWork W2206346680 @default.
• W2000510502 hasRelatedWork W2349128994 @default.
• W2000510502 hasRelatedWork W2358420625 @default.
• W2000510502 hasRelatedWork W2466826031 @default.
• W2000510502 hasRelatedWork W2734752905 @default.
• W2000510502 hasRelatedWork W2739653843 @default.
• W2000510502 hasRelatedWork W4280516166 @default.
• W2000510502 hasVolume "43" @default.
• W2000510502 isParatext "false" @default.
• W2000510502 isRetracted "false" @default.
• W2000510502 magId "2000510502" @default.
• W2000510502 workType "article" @default.