FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000514960> ?p ?o ?g. }

• W2000514960 endingPage "210" @default.
• W2000514960 startingPage "207" @default.
• W2000514960 abstract "Berberine, an isoquinoline alkaloid is reported to modulate several neurotransmitter systems like N-methyl-D-aspartate, nitric oxide and serotonin, which modulate convulsions. In addition, it is suggested that Berberis vulgaris may be useful in treatment of convulsion and epilepsy. Therefore, the present study investigated the effects of berberine in pentylenetetrazole, maximal electroshock (MES) and kainic acid (KA)-induced convulsions. The latency for development of convulsions and mortality rate was recorded in these models using mice. The results revealed that in MES-induced seizures model, berberine (10 and 20 mg/kg, i.p.) decreased duration of tonic hind limb extension and percent mortality. Moreover, these doses of berberine also protected mice against KA-induced clonic convulsions and decreased mortality. Berberine also protected mice against NMDA-induced turning behavior. Further, the anticonvulsant doses of berberine did not show any signs of motor in-coordination when tested in rotarod test. In conclusion, berberine exhibits anticonvulsant activity by modulating neurotransmitter systems and may find clinical application." @default.
• W2000514960 created "2016-06-24" @default.
• W2000514960 creator A5038419218 @default.
• W2000514960 creator A5040995764 @default.
• W2000514960 creator A5041118271 @default.
• W2000514960 creator A5070460442 @default.
• W2000514960 creator A5083555727 @default.
• W2000514960 creator A5087712338 @default.
• W2000514960 date "2010-07-01" @default.
• W2000514960 modified "2023-09-29" @default.
• W2000514960 title "Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice" @default.
• W2000514960 cites W1501358501 @default.
• W2000514960 cites W1971354069 @default.
• W2000514960 cites W1974809694 @default.
• W2000514960 cites W1976465428 @default.
• W2000514960 cites W1981864637 @default.
• W2000514960 cites W1983257232 @default.
• W2000514960 cites W1988521712 @default.
• W2000514960 cites W1990988934 @default.
• W2000514960 cites W1996261944 @default.
• W2000514960 cites W1997545922 @default.
• W2000514960 cites W1999218050 @default.
• W2000514960 cites W2003642304 @default.
• W2000514960 cites W2011155003 @default.
• W2000514960 cites W2012665219 @default.
• W2000514960 cites W2017061363 @default.
• W2000514960 cites W2018021139 @default.
• W2000514960 cites W2036140592 @default.
• W2000514960 cites W2037125682 @default.
• W2000514960 cites W2055585726 @default.
• W2000514960 cites W2071589574 @default.
• W2000514960 cites W2079224783 @default.
• W2000514960 cites W2079927834 @default.
• W2000514960 cites W2081460149 @default.
• W2000514960 cites W2087316360 @default.
• W2000514960 cites W2120996135 @default.
• W2000514960 cites W2130793314 @default.
• W2000514960 cites W2143268844 @default.
• W2000514960 cites W2143877891 @default.
• W2000514960 cites W2156936624 @default.
• W2000514960 cites W2328931461 @default.
• W2000514960 doi "https://doi.org/10.1016/j.yebeh.2010.03.007" @default.
• W2000514960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20638957" @default.
• W2000514960 hasPublicationYear "2010" @default.
• W2000514960 type Work @default.
• W2000514960 sameAs 2000514960 @default.
• W2000514960 citedByCount "97" @default.
• W2000514960 countsByYear W20005149602012 @default.
• W2000514960 countsByYear W20005149602013 @default.
• W2000514960 countsByYear W20005149602014 @default.
• W2000514960 countsByYear W20005149602015 @default.
• W2000514960 countsByYear W20005149602016 @default.
• W2000514960 countsByYear W20005149602017 @default.
• W2000514960 countsByYear W20005149602018 @default.
• W2000514960 countsByYear W20005149602019 @default.
• W2000514960 countsByYear W20005149602020 @default.
• W2000514960 countsByYear W20005149602021 @default.
• W2000514960 countsByYear W20005149602022 @default.
• W2000514960 countsByYear W20005149602023 @default.
• W2000514960 crossrefType "journal-article" @default.
• W2000514960 hasAuthorship W2000514960A5038419218 @default.
• W2000514960 hasAuthorship W2000514960A5040995764 @default.
• W2000514960 hasAuthorship W2000514960A5041118271 @default.
• W2000514960 hasAuthorship W2000514960A5070460442 @default.
• W2000514960 hasAuthorship W2000514960A5083555727 @default.
• W2000514960 hasAuthorship W2000514960A5087712338 @default.
• W2000514960 hasConcept C118552586 @default.
• W2000514960 hasConcept C126322002 @default.
• W2000514960 hasConcept C170493617 @default.
• W2000514960 hasConcept C185592680 @default.
• W2000514960 hasConcept C2775858608 @default.
• W2000514960 hasConcept C2775864247 @default.
• W2000514960 hasConcept C2776108384 @default.
• W2000514960 hasConcept C2776923262 @default.
• W2000514960 hasConcept C2777010014 @default.
• W2000514960 hasConcept C2777667214 @default.
• W2000514960 hasConcept C2778186239 @default.
• W2000514960 hasConcept C2780116568 @default.
• W2000514960 hasConcept C42219234 @default.
• W2000514960 hasConcept C519581460 @default.
• W2000514960 hasConcept C55493867 @default.
• W2000514960 hasConcept C61174792 @default.
• W2000514960 hasConcept C71240020 @default.
• W2000514960 hasConcept C71924100 @default.
• W2000514960 hasConcept C98274493 @default.
• W2000514960 hasConcept C99631742 @default.
• W2000514960 hasConceptScore W2000514960C118552586 @default.
• W2000514960 hasConceptScore W2000514960C126322002 @default.
• W2000514960 hasConceptScore W2000514960C170493617 @default.
• W2000514960 hasConceptScore W2000514960C185592680 @default.
• W2000514960 hasConceptScore W2000514960C2775858608 @default.
• W2000514960 hasConceptScore W2000514960C2775864247 @default.
• W2000514960 hasConceptScore W2000514960C2776108384 @default.
• W2000514960 hasConceptScore W2000514960C2776923262 @default.
• W2000514960 hasConceptScore W2000514960C2777010014 @default.
• W2000514960 hasConceptScore W2000514960C2777667214 @default.
• W2000514960 hasConceptScore W2000514960C2778186239 @default.
• W2000514960 hasConceptScore W2000514960C2780116568 @default.

• next