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- W2000517822 abstract "The effective design and control of a capillary electrophoresis (CE) microchip requires a thorough understanding of the electrokinetic transport phenomena associated with its microfluidic injection system. The present study utilizes a numerical simulation approach to investigate these electrokinetic transport processes and to study the control parameters of the injection process. Injection systems with a variety of different configurations are designed and tested, including the cross-form, T-form, double-T-form, variable-volume focused flow cross-form, and variable-volume triple-T-form configuration. Each injection system cycles through a predetermined series of steps in which the magnitudes and distributions of the applied electric field are precisely manipulated in order to effectuate a virtual valve. This study investigates the sample leakage effect associated with each of the injection configurations and applies the double-L, pullback, and focusing injection techniques to minimize the sample leakage effect. The injection methods presented in this paper have the exciting potential for use in high-quality, high-throughput chemical analysis applications and throughout the micro-total-analysis systems field." @default.
- W2000517822 created "2016-06-24" @default.
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- W2000517822 date "2005-02-01" @default.
- W2000517822 modified "2023-10-16" @default.
- W2000517822 title "Numerical simulation of electrokinetic injection techniques in capillary electrophoresis microchips" @default.
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- W2000517822 doi "https://doi.org/10.1002/elps.200410032" @default.
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