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- W2000519006 abstract "The use of monoclonal antibodies (MAbs) as radiation carriers in argeted radiotherapy of cancers has produced striking clinical responses in hematologic diseases, such as non-Hodgkin’s lymphoma. Novel strategies are currently being examined in an effort to improve efficacy in solid tumor therapies. Two of these strategies involve minimizing the systemic toxicity of a circulating radionuclide via ‘pretargeting’, and the sensitization of tumors to radiation by combination therapy with radiosensitizing drugs. Advances made in radiolabeling chemistries and in the use of alpha-particle emitters can also improve utility. Clinical evidence suggests that radioimmunotherapy may be best applied in minimal-disease and adjuvant settings in combination with other cancer therapy modalities." @default.
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- W2000519006 date "2007-03-01" @default.
- W2000519006 modified "2023-10-14" @default.
- W2000519006 title "862 RADIOIMMUNOTHERAPY OF ADVANCED RENAL CELL CARCINOMA PATIENTS WITH LUTETIUM-177 LABELED MONOCLONAL ANTIBODY CG250" @default.
- W2000519006 doi "https://doi.org/10.1016/s1569-9056(07)60857-4" @default.
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