Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000519842> ?p ?o ?g. }
- W2000519842 endingPage "813" @default.
- W2000519842 startingPage "806" @default.
- W2000519842 abstract "Bacteria divide by forming a contractile ring around their midcell region. FtsZ, a cytoskeletal soluble protein structurally related to tubulin, is the main component of this division machinery. It forms filaments that bundle at the inner side of the cytoplasmic membrane. These FtsZ bundles do not attach to bare lipid surfaces. In Escherichia coli they remain near the membrane surface by attaching to the membrane protein ZipA and FtsA. In order to study the structure and dynamics of the ZipA–FtsZ bundles formed on a lipid surface, we have oriented a soluble form of ZipA (sZipA), with its transmembrane domain substituted by a histidine tag, on supported lipid membranes. Atomic force microscopy has been used to visualize the polymers formed on top of this biomimetic surface. In the presence of GTP, when sZipA is present, FtsZ polymers restructure forming higher order structures. The lipid composition of the underlying membrane affects the aggregation kinetics and the shape of the structures formed. On the negatively charged E. coli lipid membranes, filaments condense from initially disperse material to form a network that is more dynamic and flexible than the one formed on phosphatidyl choline bilayers. These FtsZ–ZipA filament bundles are interconnected, retain their capacity to dynamically restructure, to fragment, to anneal and to condense laterally." @default.
- W2000519842 created "2016-06-24" @default.
- W2000519842 creator A5012955525 @default.
- W2000519842 creator A5024970618 @default.
- W2000519842 creator A5027468970 @default.
- W2000519842 creator A5028354833 @default.
- W2000519842 creator A5032071372 @default.
- W2000519842 creator A5048282739 @default.
- W2000519842 creator A5085580463 @default.
- W2000519842 creator A5088907700 @default.
- W2000519842 date "2012-03-01" @default.
- W2000519842 modified "2023-10-03" @default.
- W2000519842 title "FtsZ polymers bound to lipid bilayers through ZipA form dynamic two dimensional networks" @default.
- W2000519842 cites W1502692131 @default.
- W2000519842 cites W1505479679 @default.
- W2000519842 cites W1643603004 @default.
- W2000519842 cites W1714832738 @default.
- W2000519842 cites W1973044434 @default.
- W2000519842 cites W1974066748 @default.
- W2000519842 cites W1978829580 @default.
- W2000519842 cites W1981242878 @default.
- W2000519842 cites W1991468568 @default.
- W2000519842 cites W1993726142 @default.
- W2000519842 cites W1995300949 @default.
- W2000519842 cites W2000214816 @default.
- W2000519842 cites W2004547176 @default.
- W2000519842 cites W2012690367 @default.
- W2000519842 cites W2017853580 @default.
- W2000519842 cites W2026428622 @default.
- W2000519842 cites W2027620887 @default.
- W2000519842 cites W2032459185 @default.
- W2000519842 cites W2035468215 @default.
- W2000519842 cites W2036158497 @default.
- W2000519842 cites W2038091759 @default.
- W2000519842 cites W2044524542 @default.
- W2000519842 cites W2045721146 @default.
- W2000519842 cites W2046968191 @default.
- W2000519842 cites W2052800057 @default.
- W2000519842 cites W2068603795 @default.
- W2000519842 cites W2070067221 @default.
- W2000519842 cites W2077546260 @default.
- W2000519842 cites W2078205405 @default.
- W2000519842 cites W2092065855 @default.
- W2000519842 cites W2095750018 @default.
- W2000519842 cites W2105909402 @default.
- W2000519842 cites W2113989429 @default.
- W2000519842 cites W2114000891 @default.
- W2000519842 cites W2114801314 @default.
- W2000519842 cites W2126055327 @default.
- W2000519842 cites W2126211773 @default.
- W2000519842 cites W2129363846 @default.
- W2000519842 cites W2129624268 @default.
- W2000519842 cites W2132375330 @default.
- W2000519842 cites W2142779706 @default.
- W2000519842 cites W2160337123 @default.
- W2000519842 cites W2599199563 @default.
- W2000519842 doi "https://doi.org/10.1016/j.bbamem.2011.12.012" @default.
- W2000519842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22198391" @default.
- W2000519842 hasPublicationYear "2012" @default.
- W2000519842 type Work @default.
- W2000519842 sameAs 2000519842 @default.
- W2000519842 citedByCount "41" @default.
- W2000519842 countsByYear W20005198422012 @default.
- W2000519842 countsByYear W20005198422013 @default.
- W2000519842 countsByYear W20005198422014 @default.
- W2000519842 countsByYear W20005198422015 @default.
- W2000519842 countsByYear W20005198422016 @default.
- W2000519842 countsByYear W20005198422017 @default.
- W2000519842 countsByYear W20005198422018 @default.
- W2000519842 countsByYear W20005198422019 @default.
- W2000519842 countsByYear W20005198422020 @default.
- W2000519842 countsByYear W20005198422021 @default.
- W2000519842 countsByYear W20005198422022 @default.
- W2000519842 crossrefType "journal-article" @default.
- W2000519842 hasAuthorship W2000519842A5012955525 @default.
- W2000519842 hasAuthorship W2000519842A5024970618 @default.
- W2000519842 hasAuthorship W2000519842A5027468970 @default.
- W2000519842 hasAuthorship W2000519842A5028354833 @default.
- W2000519842 hasAuthorship W2000519842A5032071372 @default.
- W2000519842 hasAuthorship W2000519842A5048282739 @default.
- W2000519842 hasAuthorship W2000519842A5085580463 @default.
- W2000519842 hasAuthorship W2000519842A5088907700 @default.
- W2000519842 hasConcept C12554922 @default.
- W2000519842 hasConcept C14228908 @default.
- W2000519842 hasConcept C142669718 @default.
- W2000519842 hasConcept C1491633281 @default.
- W2000519842 hasConcept C185592680 @default.
- W2000519842 hasConcept C20418707 @default.
- W2000519842 hasConcept C2776237524 @default.
- W2000519842 hasConcept C39944091 @default.
- W2000519842 hasConcept C41625074 @default.
- W2000519842 hasConcept C55493867 @default.
- W2000519842 hasConcept C8010536 @default.
- W2000519842 hasConcept C84425145 @default.
- W2000519842 hasConcept C86803240 @default.
- W2000519842 hasConcept C95444343 @default.
- W2000519842 hasConceptScore W2000519842C12554922 @default.
- W2000519842 hasConceptScore W2000519842C14228908 @default.