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• W2000525079 abstract "Non-invasive and effective cell recovery from culture substrates is important for the passage and characterization of cells. In this study, a photoreactive polymer surface, which uses UV-irradiation to control substrate cell adhesion, was prepared. The photoreactive phospholipid polymer (PMB-PL) reported herein, was composed of a both 2-methacryloyloxyethyl phosphorylcholine (MPC) unit as a cytocompatible unit and methacrylate bearing a photolabile nitrobenzyl group. The PMB-PL polymer was used to coat a cell culture substrate thus affording a photoreactive surface. Surface analysis of the PMB-PL coating indicated a strong photoresponse owing to the sensitivity of the PL unit. Before light exposure, the PMB-PL surface provided cell adhesion. Following UV-irradiation, the PMB-PL coating was converted to a neutral ζ-potential and hydrophilic surface. The photoreactive surface conversion process allowed for the detachment of adhered cells from the PMB-PL surface while maintaining cell viability. This study demonstrates the promise and significance of the PMB-PL photoreactive surface as a method to control cell attachment and detachment for cell function investigation." @default.
• W2000525079 created "2016-06-24" @default.
• W2000525079 creator A5005237164 @default.
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• W2000525079 date "2012-11-01" @default.
• W2000525079 modified "2023-10-18" @default.
• W2000525079 title "Cell adhesion control on photoreactive phospholipid polymer surfaces" @default.
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• W2000525079 doi "https://doi.org/10.1016/j.colsurfb.2011.08.029" @default.
• W2000525079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21982212" @default.
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