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- W2000525439 abstract "Incubation of rat peritoneal macrophages with the bacterial product lipopolysaccharide (LPS) caused significant increases in the production of nitrite, a stable endproduct of nitric oxide (NO). Addition of the digitalis-derived glycoside ouabain, which alone is without effect, significantly enhanced the stimulating effects of LPS. The Na+ ionophore monensin was without any effect, while the Ca2+ ionophore A23187, like ouabain, enhanced the effect of LPS. Thus ouabain may enhance the LPS-stimulated NO production in rat peritoneal macrophages via still unknown mechanisms in which Ca2+ ions are most likely involved." @default.
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- W2000525439 title "Ouabain enhances the lipopolysaccharide-induced nitric oxide production by rat peritoneal macrophages" @default.
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- W2000525439 doi "https://doi.org/10.1016/s0162-3109(96)00159-2" @default.
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