FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000528840> ?p ?o ?g. }

• W2000528840 endingPage "666" @default.
• W2000528840 startingPage "661" @default.
• W2000528840 abstract "The present study has evaluated the chemopreventive effects of gossypol on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis and on human gastric adenocarcinoma (AGS) cell line. Gossypol, C(30)H(30)O(8), is a polyphenolic compound that has anti proliferative effect and induces apoptosis in various cancer cells. The aim of this work was to delineate in vivo and in vitro anti-initiating mechanisms of orally administered gossypol in target (stomach) tissues and in human gastric adenocarcinoma (AGS) cell line. In vitro results prove that gossypol has potent cytotoxic effect and inhibit the proliferation of adenocarcinoma (AGS) cell line. In vivo results prove gossypol to be successful in prolonging the survival of MNNG induced cancer bearing animals and in delaying the onset of tumor in animals administrated with gossypol and MNNG simultaneously. Examination of the target (stomach) tissues in sacrificed experimental animals shows that administration of gossypol significantly reduces the level of tumor marker enzyme (carcino embryonic antigen) and pepsin. The level of Nucleic acid contents (DNA and RNA) significantly reduces, and the membrane damage of glycoprotein subsides, in the target tissues of cancer bearing animals, with the administration of gossypol. These data suggest that gossypol may create a beneficial effect in patients with gastric cancer." @default.
• W2000528840 created "2016-06-24" @default.
• W2000528840 creator A5005328292 @default.
• W2000528840 creator A5052514463 @default.
• W2000528840 creator A5055785315 @default.
• W2000528840 creator A5066307674 @default.
• W2000528840 date "2011-08-01" @default.
• W2000528840 modified "2023-09-27" @default.
• W2000528840 title "In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer" @default.
• W2000528840 cites W1544860636 @default.
• W2000528840 cites W1580023435 @default.
• W2000528840 cites W1775749144 @default.
• W2000528840 cites W1786911182 @default.
• W2000528840 cites W1906197854 @default.
• W2000528840 cites W1970376753 @default.
• W2000528840 cites W1974068481 @default.
• W2000528840 cites W1974789605 @default.
• W2000528840 cites W1980098109 @default.
• W2000528840 cites W1982727838 @default.
• W2000528840 cites W1985750228 @default.
• W2000528840 cites W1995430426 @default.
• W2000528840 cites W1997789236 @default.
• W2000528840 cites W1998745828 @default.
• W2000528840 cites W1998766027 @default.
• W2000528840 cites W2007303815 @default.
• W2000528840 cites W2030222404 @default.
• W2000528840 cites W2030720355 @default.
• W2000528840 cites W2045077342 @default.
• W2000528840 cites W2045717811 @default.
• W2000528840 cites W2070446507 @default.
• W2000528840 cites W2078557270 @default.
• W2000528840 cites W2082198473 @default.
• W2000528840 cites W2126532720 @default.
• W2000528840 cites W2134200987 @default.
• W2000528840 cites W2318388129 @default.
• W2000528840 cites W2338576041 @default.
• W2000528840 cites W2406442876 @default.
• W2000528840 cites W2413775972 @default.
• W2000528840 cites W4239810383 @default.
• W2000528840 doi "https://doi.org/10.1016/j.bbrc.2011.06.167" @default.
• W2000528840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21782799" @default.
• W2000528840 hasPublicationYear "2011" @default.
• W2000528840 type Work @default.
• W2000528840 sameAs 2000528840 @default.
• W2000528840 citedByCount "14" @default.
• W2000528840 countsByYear W20005288402013 @default.
• W2000528840 countsByYear W20005288402015 @default.
• W2000528840 countsByYear W20005288402016 @default.
• W2000528840 countsByYear W20005288402017 @default.
• W2000528840 countsByYear W20005288402020 @default.
• W2000528840 countsByYear W20005288402021 @default.
• W2000528840 countsByYear W20005288402023 @default.
• W2000528840 crossrefType "journal-article" @default.
• W2000528840 hasAuthorship W2000528840A5005328292 @default.
• W2000528840 hasAuthorship W2000528840A5052514463 @default.
• W2000528840 hasAuthorship W2000528840A5055785315 @default.
• W2000528840 hasAuthorship W2000528840A5066307674 @default.
• W2000528840 hasConcept C121608353 @default.
• W2000528840 hasConcept C126322002 @default.
• W2000528840 hasConcept C150903083 @default.
• W2000528840 hasConcept C185592680 @default.
• W2000528840 hasConcept C190283241 @default.
• W2000528840 hasConcept C207001950 @default.
• W2000528840 hasConcept C2776653637 @default.
• W2000528840 hasConcept C2779422922 @default.
• W2000528840 hasConcept C2781182431 @default.
• W2000528840 hasConcept C502942594 @default.
• W2000528840 hasConcept C54355233 @default.
• W2000528840 hasConcept C55493867 @default.
• W2000528840 hasConcept C555283112 @default.
• W2000528840 hasConcept C71924100 @default.
• W2000528840 hasConcept C81885089 @default.
• W2000528840 hasConcept C86803240 @default.
• W2000528840 hasConcept C98274493 @default.
• W2000528840 hasConceptScore W2000528840C121608353 @default.
• W2000528840 hasConceptScore W2000528840C126322002 @default.
• W2000528840 hasConceptScore W2000528840C150903083 @default.
• W2000528840 hasConceptScore W2000528840C185592680 @default.
• W2000528840 hasConceptScore W2000528840C190283241 @default.
• W2000528840 hasConceptScore W2000528840C207001950 @default.
• W2000528840 hasConceptScore W2000528840C2776653637 @default.
• W2000528840 hasConceptScore W2000528840C2779422922 @default.
• W2000528840 hasConceptScore W2000528840C2781182431 @default.
• W2000528840 hasConceptScore W2000528840C502942594 @default.
• W2000528840 hasConceptScore W2000528840C54355233 @default.
• W2000528840 hasConceptScore W2000528840C55493867 @default.
• W2000528840 hasConceptScore W2000528840C555283112 @default.
• W2000528840 hasConceptScore W2000528840C71924100 @default.
• W2000528840 hasConceptScore W2000528840C81885089 @default.
• W2000528840 hasConceptScore W2000528840C86803240 @default.
• W2000528840 hasConceptScore W2000528840C98274493 @default.
• W2000528840 hasIssue "4" @default.
• W2000528840 hasLocation W20005288401 @default.
• W2000528840 hasLocation W20005288402 @default.
• W2000528840 hasOpenAccess W2000528840 @default.
• W2000528840 hasPrimaryLocation W20005288401 @default.
• W2000528840 hasRelatedWork W1499339123 @default.
• W2000528840 hasRelatedWork W2091977119 @default.

• next