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- W2000528855 abstract "The N-terminal peptides liberated in the course of the activation of bovine (Davie and Neurath (1955), Desnuelle and Fabre (1955)) porcine (Charles and al. (1963)) and ovine (Bricteux-Grégoire and al. (1966)) Tg all have in common the sequence Asp-Asp-Asp-Asp just preceding the Lys-Ile bond which is hydrolyzed as the first step in the activation. Several roles might be attributed to this sequence (Lazdunski and Delaage 1967, Delaage and Lazdunski 1967). In this paper the influence of the aspartyl residues on the tryptic specificity for the Lys-Ile bond is described. The kinetic behavior of several peptides related to the N-terminal sequence of bovine Tg, Val-Asp4-Lys-Ile-Val-Gly, is studied." @default.
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- W2000528855 date "1967-10-01" @default.
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- W2000528855 title "On the activation of trypsinogen. A study of peptide models related to the N-terminal sequence of the zymogen" @default.
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- W2000528855 doi "https://doi.org/10.1016/0006-291x(67)90593-1" @default.
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