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• W2000529621 endingPage "e277S" @default.
• W2000529621 startingPage "e263S" @default.
• W2000529621 abstract "BackgroundBronchial intraepithelial lesions may be precursors of central airway lung carcinomas. Identification and early treatment of these preinvasive lesions might prevent progression to invasive carcinoma.MethodsWe systematically reviewed the literature to develop evidence-based recommendations regarding the diagnosis and treatment of intraepithelial lesions.ResultsThe risk and timeline for progression of bronchial intraepithelial lesions to carcinoma in situ (CIS) or invasive carcinoma are not well understood. Multiple studies show that autofluorescence bronchoscopy (AFB) is more sensitive that white light bronchoscopy (WLB) to identify these lesions. In patients with severe dysplasia or CIS in sputum cytology who have chest imaging studies showing no localizing abnormality, we suggest use of WLB; AFB may be used as an adjunct when available. Patients with known severe dysplasia or CIS of central airways should be followed with WLB or AFB, when available. WLB or AFB is also suggested for patients with early lung cancer who will undergo resection for delineation of tumor margins and assessment of synchronous lesions. However, AFB is not recommended prior to endobronchial therapy for CIS or early central lung cancer. Several endobronchial techniques are recommended for the treatment of patients with superficial limited mucosal lung cancer who are not candidates for resection.ConclusionAdditional information is needed about the natural history and rate of progression of preinvasive central airway lesions. Patients with severe dysplasia or CIS may be treated endobronchially; however, it remains unclear if these therapies are associated with improved patient outcomes. Bronchial intraepithelial lesions may be precursors of central airway lung carcinomas. Identification and early treatment of these preinvasive lesions might prevent progression to invasive carcinoma. We systematically reviewed the literature to develop evidence-based recommendations regarding the diagnosis and treatment of intraepithelial lesions. The risk and timeline for progression of bronchial intraepithelial lesions to carcinoma in situ (CIS) or invasive carcinoma are not well understood. Multiple studies show that autofluorescence bronchoscopy (AFB) is more sensitive that white light bronchoscopy (WLB) to identify these lesions. In patients with severe dysplasia or CIS in sputum cytology who have chest imaging studies showing no localizing abnormality, we suggest use of WLB; AFB may be used as an adjunct when available. Patients with known severe dysplasia or CIS of central airways should be followed with WLB or AFB, when available. WLB or AFB is also suggested for patients with early lung cancer who will undergo resection for delineation of tumor margins and assessment of synchronous lesions. However, AFB is not recommended prior to endobronchial therapy for CIS or early central lung cancer. Several endobronchial techniques are recommended for the treatment of patients with superficial limited mucosal lung cancer who are not candidates for resection. Additional information is needed about the natural history and rate of progression of preinvasive central airway lesions. Patients with severe dysplasia or CIS may be treated endobronchially; however, it remains unclear if these therapies are associated with improved patient outcomes." @default.
• W2000529621 created "2016-06-24" @default.
• W2000529621 creator A5005322307 @default.
• W2000529621 creator A5009259809 @default.
• W2000529621 creator A5033612339 @default.
• W2000529621 creator A5048233175 @default.
• W2000529621 date "2013-05-01" @default.
• W2000529621 modified "2023-10-17" @default.
• W2000529621 title "Diagnosis and Treatment of Bronchial Intraepithelial Neoplasia and Early Lung Cancer of the Central Airways" @default.
• W2000529621 cites W1505708219 @default.
• W2000529621 cites W1874994109 @default.
• W2000529621 cites W1904917079 @default.
• W2000529621 cites W1963901314 @default.
• W2000529621 cites W1964240785 @default.
• W2000529621 cites W1965229752 @default.
• W2000529621 cites W1966141938 @default.
• W2000529621 cites W1967718615 @default.
• W2000529621 cites W1968876722 @default.
• W2000529621 cites W1971323871 @default.
• W2000529621 cites W1973315596 @default.
• W2000529621 cites W1974626255 @default.
• W2000529621 cites W1979299677 @default.
• W2000529621 cites W1981717206 @default.
• W2000529621 cites W1988622663 @default.
• W2000529621 cites W1992941350 @default.
• W2000529621 cites W1994000219 @default.
• W2000529621 cites W1996338047 @default.
• W2000529621 cites W2003896342 @default.
• W2000529621 cites W2003980559 @default.
• W2000529621 cites W2008397972 @default.
• W2000529621 cites W2008918070 @default.
• W2000529621 cites W2011383775 @default.
• W2000529621 cites W2012782933 @default.
• W2000529621 cites W2016923161 @default.
• W2000529621 cites W2022053033 @default.
• W2000529621 cites W2022450371 @default.
• W2000529621 cites W2025804847 @default.
• W2000529621 cites W2028296334 @default.
• W2000529621 cites W2031612731 @default.
• W2000529621 cites W2038108451 @default.
• W2000529621 cites W2038721511 @default.
• W2000529621 cites W2041632368 @default.
• W2000529621 cites W2044730030 @default.
• W2000529621 cites W2045811551 @default.
• W2000529621 cites W2046019164 @default.
• W2000529621 cites W2047529073 @default.
• W2000529621 cites W2048341192 @default.
• W2000529621 cites W2050527145 @default.
• W2000529621 cites W2053144498 @default.
• W2000529621 cites W2053217164 @default.
• W2000529621 cites W2055091408 @default.
• W2000529621 cites W2058052840 @default.
• W2000529621 cites W2059146933 @default.
• W2000529621 cites W2062248845 @default.
• W2000529621 cites W2065906711 @default.
• W2000529621 cites W2066176304 @default.
• W2000529621 cites W2066236903 @default.
• W2000529621 cites W2071869945 @default.
• W2000529621 cites W2078788551 @default.
• W2000529621 cites W2082637506 @default.
• W2000529621 cites W2084829978 @default.
• W2000529621 cites W2091283166 @default.
• W2000529621 cites W2099673225 @default.
• W2000529621 cites W2099965109 @default.
• W2000529621 cites W2101995865 @default.
• W2000529621 cites W2102275596 @default.
• W2000529621 cites W2102511272 @default.
• W2000529621 cites W2102784247 @default.
• W2000529621 cites W2103644311 @default.
• W2000529621 cites W2104996384 @default.
• W2000529621 cites W2105847947 @default.
• W2000529621 cites W2112560948 @default.
• W2000529621 cites W2115585647 @default.
• W2000529621 cites W2116069555 @default.
• W2000529621 cites W2118258556 @default.
• W2000529621 cites W2118963481 @default.
• W2000529621 cites W2123180073 @default.
• W2000529621 cites W2125078645 @default.
• W2000529621 cites W2126971170 @default.
• W2000529621 cites W2131554536 @default.
• W2000529621 cites W2134036601 @default.
• W2000529621 cites W2137086955 @default.
• W2000529621 cites W2140664514 @default.
• W2000529621 cites W2141964792 @default.
• W2000529621 cites W2145997626 @default.
• W2000529621 cites W2150772681 @default.
• W2000529621 cites W2154308385 @default.
• W2000529621 cites W2154917412 @default.
• W2000529621 cites W2156065308 @default.
• W2000529621 cites W2160029055 @default.
• W2000529621 cites W2161698422 @default.
• W2000529621 cites W2162188592 @default.
• W2000529621 cites W2162969320 @default.
• W2000529621 cites W2167495698 @default.
• W2000529621 cites W2169010443 @default.
• W2000529621 cites W2172269802 @default.
• W2000529621 cites W2190327027 @default.
• W2000529621 cites W2217055163 @default.

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