Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000531720> ?p ?o ?g. }
- W2000531720 endingPage "1520" @default.
- W2000531720 startingPage "1509" @default.
- W2000531720 abstract "The present work comprises the synthesis of ofloxacin (OFL) complexes with various transition metals. Two types of complexes [Cu(OFL)Cl2].H2O, [Pt(OFL)CI2].3H2O, [Zn(OFL)2]2CI.4H2O, [Ru(OFL)2ClH2O]2CI.4H2O, and [Fe(OFL)2Cl]2CI.5H2O were obtained. The complexes were characterized by different physicochemical, spectroscopic, and elemental analysis. The thermal decomposition behaviors of metal complexes were investigated in nitrogen atmosphere using TG and DTA techniques. Results suggest that OFL interacts with the metals as a monoanionic bidentate ligand. These complexes were also tested for their antibacterial activity against nine different microorganisms, and the results were compared with the parent drug. The electrochemical properties of all complexes have been investigated by cyclic voltammetry using glassy carbon electrode. The oxidation/reduction of metal complexes was irreversible/reversible and exhibited diffusion controlled process depending on pH. The dependence of intensities of currents and potentials on pH, concentration, scan rate, nature of the buffer was investigated. The oxidation/reduction mechanism was proposed and discussed. The DNA binding activity of the complexes was evaluated by examining their ability to bind to calf-thymus DNA (CT DNA) with UV spectroscopy. UV studies of the interaction of the OFL and complexes with DNA have shown that these compounds can bind to CT DNA. The binding constants of the OFL and complexes with CT DNA have also been calculated." @default.
- W2000531720 created "2016-06-24" @default.
- W2000531720 creator A5008551729 @default.
- W2000531720 date "2014-06-02" @default.
- W2000531720 modified "2023-10-18" @default.
- W2000531720 title "Ofloxacin Metal Complexes: Synthesis, Characterization, Analytical Properties, and DNA Binding Studies" @default.
- W2000531720 cites W1940436875 @default.
- W2000531720 cites W1972205255 @default.
- W2000531720 cites W1974870719 @default.
- W2000531720 cites W1977492525 @default.
- W2000531720 cites W1983200612 @default.
- W2000531720 cites W1984078443 @default.
- W2000531720 cites W1987765537 @default.
- W2000531720 cites W1997473545 @default.
- W2000531720 cites W1998311403 @default.
- W2000531720 cites W2003745247 @default.
- W2000531720 cites W2008264469 @default.
- W2000531720 cites W2012592778 @default.
- W2000531720 cites W2013080966 @default.
- W2000531720 cites W2014926692 @default.
- W2000531720 cites W2017162330 @default.
- W2000531720 cites W2018721879 @default.
- W2000531720 cites W2022257071 @default.
- W2000531720 cites W2022515291 @default.
- W2000531720 cites W2025226421 @default.
- W2000531720 cites W2027836293 @default.
- W2000531720 cites W2031998571 @default.
- W2000531720 cites W2033067488 @default.
- W2000531720 cites W2035033848 @default.
- W2000531720 cites W2038505751 @default.
- W2000531720 cites W2039659866 @default.
- W2000531720 cites W2046280176 @default.
- W2000531720 cites W2046865563 @default.
- W2000531720 cites W2048400546 @default.
- W2000531720 cites W2051234140 @default.
- W2000531720 cites W2051555156 @default.
- W2000531720 cites W2052365858 @default.
- W2000531720 cites W2052693328 @default.
- W2000531720 cites W2054477717 @default.
- W2000531720 cites W2055173809 @default.
- W2000531720 cites W2059513289 @default.
- W2000531720 cites W2069586606 @default.
- W2000531720 cites W2069926584 @default.
- W2000531720 cites W2083355060 @default.
- W2000531720 cites W2090624794 @default.
- W2000531720 cites W2091672124 @default.
- W2000531720 cites W2094528549 @default.
- W2000531720 cites W2107262418 @default.
- W2000531720 cites W2114443210 @default.
- W2000531720 cites W2124080554 @default.
- W2000531720 cites W2125251319 @default.
- W2000531720 cites W2128294421 @default.
- W2000531720 cites W2164813102 @default.
- W2000531720 cites W2314422062 @default.
- W2000531720 cites W4247341678 @default.
- W2000531720 cites W4249303098 @default.
- W2000531720 cites W4300919399 @default.
- W2000531720 cites W2127578681 @default.
- W2000531720 doi "https://doi.org/10.1080/15533174.2013.818020" @default.
- W2000531720 hasPublicationYear "2014" @default.
- W2000531720 type Work @default.
- W2000531720 sameAs 2000531720 @default.
- W2000531720 citedByCount "5" @default.
- W2000531720 countsByYear W20005317202017 @default.
- W2000531720 countsByYear W20005317202019 @default.
- W2000531720 countsByYear W20005317202020 @default.
- W2000531720 countsByYear W20005317202021 @default.
- W2000531720 countsByYear W20005317202022 @default.
- W2000531720 crossrefType "journal-article" @default.
- W2000531720 hasAuthorship W2000531720A5008551729 @default.
- W2000531720 hasConcept C106773901 @default.
- W2000531720 hasConcept C116569031 @default.
- W2000531720 hasConcept C121332964 @default.
- W2000531720 hasConcept C13965031 @default.
- W2000531720 hasConcept C147789679 @default.
- W2000531720 hasConcept C161790260 @default.
- W2000531720 hasConcept C170493617 @default.
- W2000531720 hasConcept C17525397 @default.
- W2000531720 hasConcept C178516000 @default.
- W2000531720 hasConcept C178790620 @default.
- W2000531720 hasConcept C179104552 @default.
- W2000531720 hasConcept C185592680 @default.
- W2000531720 hasConcept C2777869211 @default.
- W2000531720 hasConcept C2778049240 @default.
- W2000531720 hasConcept C2778512257 @default.
- W2000531720 hasConcept C3288061 @default.
- W2000531720 hasConcept C45902088 @default.
- W2000531720 hasConcept C501593827 @default.
- W2000531720 hasConcept C52859227 @default.
- W2000531720 hasConcept C544153396 @default.
- W2000531720 hasConcept C552990157 @default.
- W2000531720 hasConcept C55493867 @default.
- W2000531720 hasConcept C62520636 @default.
- W2000531720 hasConcept C71240020 @default.
- W2000531720 hasConcept C8010536 @default.
- W2000531720 hasConceptScore W2000531720C106773901 @default.
- W2000531720 hasConceptScore W2000531720C116569031 @default.
- W2000531720 hasConceptScore W2000531720C121332964 @default.