FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000532157> ?p ?o ?g. }

• W2000532157 endingPage "222" @default.
• W2000532157 startingPage "216" @default.
• W2000532157 abstract "The current study investigated the possible inherent relationship between convulsions and sleep involving the GABA(A)/benzodiazepine site complex. The aim of this study was to determine if rats with high (HTR) and low (LTR) thresholds for clonic convulsions induced by DMCM, a benzodiazepine inverse agonist, differ in the following aspects: (1) sensitivity to the hypnotic effects of the GABA(A) positive allosteric modulators diazepam, pentobarbital and ethanol and (2) in the binding of [(3)H]-flunitrazepam, a benzodiazepine agonist, measured by autoradiography, and [(3)H]-Ro 15-4513, a benzodiazepine partial inverse agonist, to membranes from discrete brain regions. The LTR subgroup presented a shorter diazepam-induced sleeping time compared to that of the HTR subgroup. Biochemical assays revealed that the LTR subgroup did not differ in [(3)H]-flunitrazepam binding compared to the HTR subgroup. With respect to the binding of [(3)H]-Ro 15-4513, the LTR subgroup had higher binding in the brainstem and lower binding in the striatum compared to the HTR subgroup. These results suggest that differences in the benzodiazepine site on the GABA(A) receptor may underlie the susceptibility to DMCM-induced convulsions and sensitivity to the hypnotic effect of diazepam." @default.
• W2000532157 created "2016-06-24" @default.
• W2000532157 creator A5064405395 @default.
• W2000532157 creator A5068165542 @default.
• W2000532157 creator A5069466726 @default.
• W2000532157 creator A5077648363 @default.
• W2000532157 date "2012-02-01" @default.
• W2000532157 modified "2023-09-24" @default.
• W2000532157 title "Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [3H]-Ro 15-4513 binding" @default.
• W2000532157 cites W133999375 @default.
• W2000532157 cites W1775749144 @default.
• W2000532157 cites W1964819203 @default.
• W2000532157 cites W1967395257 @default.
• W2000532157 cites W1970851102 @default.
• W2000532157 cites W1973357433 @default.
• W2000532157 cites W1978340986 @default.
• W2000532157 cites W1980014469 @default.
• W2000532157 cites W1980018530 @default.
• W2000532157 cites W1983621709 @default.
• W2000532157 cites W1991633205 @default.
• W2000532157 cites W1993926377 @default.
• W2000532157 cites W1995692468 @default.
• W2000532157 cites W1997416795 @default.
• W2000532157 cites W1997967494 @default.
• W2000532157 cites W2007340476 @default.
• W2000532157 cites W2010692367 @default.
• W2000532157 cites W2013029414 @default.
• W2000532157 cites W2017659544 @default.
• W2000532157 cites W2034485930 @default.
• W2000532157 cites W2034932565 @default.
• W2000532157 cites W2039518601 @default.
• W2000532157 cites W2039729897 @default.
• W2000532157 cites W2043007292 @default.
• W2000532157 cites W2046713855 @default.
• W2000532157 cites W2049381848 @default.
• W2000532157 cites W2051320847 @default.
• W2000532157 cites W2064262991 @default.
• W2000532157 cites W2064887450 @default.
• W2000532157 cites W2066475453 @default.
• W2000532157 cites W2069543630 @default.
• W2000532157 cites W2077378517 @default.
• W2000532157 cites W2093117551 @default.
• W2000532157 cites W2094036203 @default.
• W2000532157 cites W2095560457 @default.
• W2000532157 cites W2102690246 @default.
• W2000532157 cites W2116251480 @default.
• W2000532157 cites W2127051764 @default.
• W2000532157 cites W2127387181 @default.
• W2000532157 cites W2129724512 @default.
• W2000532157 cites W2149190102 @default.
• W2000532157 cites W2163815564 @default.
• W2000532157 cites W2165236934 @default.
• W2000532157 cites W2170901091 @default.
• W2000532157 cites W2419113081 @default.
• W2000532157 doi "https://doi.org/10.1016/j.eplepsyres.2011.09.014" @default.
• W2000532157 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22005005" @default.
• W2000532157 hasPublicationYear "2012" @default.
• W2000532157 type Work @default.
• W2000532157 sameAs 2000532157 @default.
• W2000532157 citedByCount "1" @default.
• W2000532157 countsByYear W20005321572012 @default.
• W2000532157 crossrefType "journal-article" @default.
• W2000532157 hasAuthorship W2000532157A5064405395 @default.
• W2000532157 hasAuthorship W2000532157A5068165542 @default.
• W2000532157 hasAuthorship W2000532157A5069466726 @default.
• W2000532157 hasAuthorship W2000532157A5077648363 @default.
• W2000532157 hasConcept C166342909 @default.
• W2000532157 hasConcept C170493617 @default.
• W2000532157 hasConcept C185592680 @default.
• W2000532157 hasConcept C2776175493 @default.
• W2000532157 hasConcept C2778173252 @default.
• W2000532157 hasConcept C2778938600 @default.
• W2000532157 hasConcept C2780930544 @default.
• W2000532157 hasConcept C2781442855 @default.
• W2000532157 hasConcept C55493867 @default.
• W2000532157 hasConcept C58732023 @default.
• W2000532157 hasConcept C71924100 @default.
• W2000532157 hasConcept C89951826 @default.
• W2000532157 hasConcept C98274493 @default.
• W2000532157 hasConceptScore W2000532157C166342909 @default.
• W2000532157 hasConceptScore W2000532157C170493617 @default.
• W2000532157 hasConceptScore W2000532157C185592680 @default.
• W2000532157 hasConceptScore W2000532157C2776175493 @default.
• W2000532157 hasConceptScore W2000532157C2778173252 @default.
• W2000532157 hasConceptScore W2000532157C2778938600 @default.
• W2000532157 hasConceptScore W2000532157C2780930544 @default.
• W2000532157 hasConceptScore W2000532157C2781442855 @default.
• W2000532157 hasConceptScore W2000532157C55493867 @default.
• W2000532157 hasConceptScore W2000532157C58732023 @default.
• W2000532157 hasConceptScore W2000532157C71924100 @default.
• W2000532157 hasConceptScore W2000532157C89951826 @default.
• W2000532157 hasConceptScore W2000532157C98274493 @default.
• W2000532157 hasIssue "2-3" @default.
• W2000532157 hasLocation W20005321571 @default.
• W2000532157 hasLocation W20005321572 @default.
• W2000532157 hasOpenAccess W2000532157 @default.
• W2000532157 hasPrimaryLocation W20005321571 @default.
• W2000532157 hasRelatedWork W1992946558 @default.

• next