FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000540088> ?p ?o ?g. }

• W2000540088 endingPage "333" @default.
• W2000540088 startingPage "327" @default.
• W2000540088 abstract "To date, it is unknown whether fexofenadine mitigates the worsening of symptoms induced by the cat allergen Felis domesticus allergen 1.To determine the effects of a single dose of fexofenadine hydrochloride, 180 mg, in preventing and controlling cat allergen-induced allergic rhinitis symptoms using the cat room challenge model.This single-center, randomized, double-blind, placebo-controlled, 2-way crossover study consisted of a screening visit, 1 or 2 qualifying visits, and 2 treatment periods separated by a mean +/- SD washout period of 14 +/- 3 days. Patients were randomized to treatment sequence 1 (placebo followed by fexofenadine) or sequence 2 (fexofenadine followed by placebo). Baseline end points were obtained before study drug administration, and allergen challenges were initiated 1 1/2 hours after dosing. The primary end point was the change from predose baseline in the total symptom score (sum of rhinorrhea, itchy nose/palate/ throat, sneezing, and itchy/watery/red eyes) after 30 minutes of allergen exposure compared with placebo.Of 211 patients screened, 66 were randomized and 63 completed the study. Mean change in the total symptom score from predose baseline was significantly less with fexofenadine compared with placebo 30 minutes after initiation of the cat allergen challenge (2 hours after dosing) (P = .03). The overall incidence of treatment-emergent adverse events was low and comparable for both groups.Prophylactic treatment with a single dose of fexofenadine hydrochloride, 180 mg, significantly mitigated the worsening of allergic rhinitis symptoms induced by exposure to cat allergen compared with placebo use." @default.
• W2000540088 created "2016-06-24" @default.
• W2000540088 creator A5005818892 @default.
• W2000540088 creator A5011083127 @default.
• W2000540088 creator A5025047595 @default.
• W2000540088 creator A5036488634 @default.
• W2000540088 creator A5042407516 @default.
• W2000540088 creator A5042436405 @default.
• W2000540088 creator A5053184162 @default.
• W2000540088 creator A5062406701 @default.
• W2000540088 date "2006-02-01" @default.
• W2000540088 modified "2023-09-23" @default.
• W2000540088 title "Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis" @default.
• W2000540088 cites W1964226776 @default.
• W2000540088 cites W1968397091 @default.
• W2000540088 cites W1971149480 @default.
• W2000540088 cites W1973319846 @default.
• W2000540088 cites W1974234028 @default.
• W2000540088 cites W1993310198 @default.
• W2000540088 cites W1999578660 @default.
• W2000540088 cites W2004984098 @default.
• W2000540088 cites W2036002783 @default.
• W2000540088 cites W2040544503 @default.
• W2000540088 cites W2049801338 @default.
• W2000540088 cites W2050864902 @default.
• W2000540088 cites W2069934070 @default.
• W2000540088 cites W2071975543 @default.
• W2000540088 cites W2081455966 @default.
• W2000540088 cites W2105066084 @default.
• W2000540088 cites W2106563551 @default.
• W2000540088 cites W2132935368 @default.
• W2000540088 cites W2153557635 @default.
• W2000540088 cites W2164865783 @default.
• W2000540088 doi "https://doi.org/10.1016/s1081-1206(10)61243-4" @default.
• W2000540088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16498855" @default.
• W2000540088 hasPublicationYear "2006" @default.
• W2000540088 type Work @default.
• W2000540088 sameAs 2000540088 @default.
• W2000540088 citedByCount "14" @default.
• W2000540088 countsByYear W20005400882013 @default.
• W2000540088 countsByYear W20005400882015 @default.
• W2000540088 countsByYear W20005400882016 @default.
• W2000540088 countsByYear W20005400882017 @default.
• W2000540088 countsByYear W20005400882019 @default.
• W2000540088 countsByYear W20005400882022 @default.
• W2000540088 countsByYear W20005400882023 @default.
• W2000540088 crossrefType "journal-article" @default.
• W2000540088 hasAuthorship W2000540088A5005818892 @default.
• W2000540088 hasAuthorship W2000540088A5011083127 @default.
• W2000540088 hasAuthorship W2000540088A5025047595 @default.
• W2000540088 hasAuthorship W2000540088A5036488634 @default.
• W2000540088 hasAuthorship W2000540088A5042407516 @default.
• W2000540088 hasAuthorship W2000540088A5042436405 @default.
• W2000540088 hasAuthorship W2000540088A5053184162 @default.
• W2000540088 hasAuthorship W2000540088A5062406701 @default.
• W2000540088 hasConcept C126322002 @default.
• W2000540088 hasConcept C142724271 @default.
• W2000540088 hasConcept C168563851 @default.
• W2000540088 hasConcept C197934379 @default.
• W2000540088 hasConcept C203014093 @default.
• W2000540088 hasConcept C204787440 @default.
• W2000540088 hasConcept C207480886 @default.
• W2000540088 hasConcept C27081682 @default.
• W2000540088 hasConcept C2776711289 @default.
• W2000540088 hasConcept C2777288759 @default.
• W2000540088 hasConcept C2779699568 @default.
• W2000540088 hasConcept C2780510475 @default.
• W2000540088 hasConcept C42219234 @default.
• W2000540088 hasConcept C71924100 @default.
• W2000540088 hasConcept C87813604 @default.
• W2000540088 hasConcept C98274493 @default.
• W2000540088 hasConceptScore W2000540088C126322002 @default.
• W2000540088 hasConceptScore W2000540088C142724271 @default.
• W2000540088 hasConceptScore W2000540088C168563851 @default.
• W2000540088 hasConceptScore W2000540088C197934379 @default.
• W2000540088 hasConceptScore W2000540088C203014093 @default.
• W2000540088 hasConceptScore W2000540088C204787440 @default.
• W2000540088 hasConceptScore W2000540088C207480886 @default.
• W2000540088 hasConceptScore W2000540088C27081682 @default.
• W2000540088 hasConceptScore W2000540088C2776711289 @default.
• W2000540088 hasConceptScore W2000540088C2777288759 @default.
• W2000540088 hasConceptScore W2000540088C2779699568 @default.
• W2000540088 hasConceptScore W2000540088C2780510475 @default.
• W2000540088 hasConceptScore W2000540088C42219234 @default.
• W2000540088 hasConceptScore W2000540088C71924100 @default.
• W2000540088 hasConceptScore W2000540088C87813604 @default.
• W2000540088 hasConceptScore W2000540088C98274493 @default.
• W2000540088 hasIssue "2" @default.
• W2000540088 hasLocation W20005400881 @default.
• W2000540088 hasLocation W20005400882 @default.
• W2000540088 hasOpenAccess W2000540088 @default.
• W2000540088 hasPrimaryLocation W20005400881 @default.
• W2000540088 hasRelatedWork W1965474331 @default.
• W2000540088 hasRelatedWork W2030308013 @default.
• W2000540088 hasRelatedWork W2033211028 @default.
• W2000540088 hasRelatedWork W2052355330 @default.
• W2000540088 hasRelatedWork W2097136564 @default.
• W2000540088 hasRelatedWork W2107187998 @default.

• next