FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000542328> ?p ?o ?g. }

• W2000542328 endingPage "928" @default.
• W2000542328 startingPage "920" @default.
• W2000542328 abstract "Abstract Establishment of mouse spermatogonial stem cell (SSC) culture systems offers a useful stem cell model for studies of proliferation and self‐renewal of mammalian germline stem cells. In addition, spontaneous development of pluripotent stem cells from cultured SSCs emphasizes their possible applications in regenerative medicine as a substitute for embryonic stem cells (ESCs). These pluripotent stem cells termed multipotent germline stem cells (mGSCs) or germline‐derived pluripotent stem cells (gPSCs) exhibit almost identical properties in terms of morphology and gene expression patterns to mouse ESCs (mESCs). In this study, to help understand mechanisms underlying reprogramming of SSCs into pluripotent stem cells, we established a culture system of SSCs derived from mice harboring green fluorescence protein (GFP) transgene whose expression is modulated by Oct4 regulatory sequences. Our results indicated that GFP intensity faithfully reflected cellular states upon reprogramming of SSCs or treatment with a selective extracellular signal‐regulated kinase (ERK) inhibitor PD0325901. Moreover, in contrast to mESCs, regulation of Nanog expression did not appear to couple to the Oct4 level in SSCs. Further analysis of Oct4‐GFP SSCs demonstrated that a posttranscriptional control of pluripotency marker genes such as Oct4 and Sox2 might play an important role as an inhibitory mechanism preventing the acquisition of pluripotency. J. Cell. Biochem. 114: 920–928, 2013. © 2012 Wiley Periodicals, Inc." @default.
• W2000542328 created "2016-06-24" @default.
• W2000542328 creator A5016779636 @default.
• W2000542328 creator A5055245414 @default.
• W2000542328 creator A5063384634 @default.
• W2000542328 creator A5067331034 @default.
• W2000542328 date "2013-02-18" @default.
• W2000542328 modified "2023-10-11" @default.
• W2000542328 title "Characterization of Oct4-GFP spermatogonial stem cell line and its application in the reprogramming studies" @default.
• W2000542328 cites W1516316082 @default.
• W2000542328 cites W1573532220 @default.
• W2000542328 cites W1975163937 @default.
• W2000542328 cites W1977825177 @default.
• W2000542328 cites W1984566122 @default.
• W2000542328 cites W2002120333 @default.
• W2000542328 cites W2013518855 @default.
• W2000542328 cites W2021900296 @default.
• W2000542328 cites W2022103408 @default.
• W2000542328 cites W2033042516 @default.
• W2000542328 cites W2037055772 @default.
• W2000542328 cites W2037979286 @default.
• W2000542328 cites W2039551265 @default.
• W2000542328 cites W2045307818 @default.
• W2000542328 cites W2054939637 @default.
• W2000542328 cites W2057061886 @default.
• W2000542328 cites W2057641163 @default.
• W2000542328 cites W2058521801 @default.
• W2000542328 cites W2058553974 @default.
• W2000542328 cites W2073738799 @default.
• W2000542328 cites W2085808496 @default.
• W2000542328 cites W2088128367 @default.
• W2000542328 cites W2091828111 @default.
• W2000542328 cites W2099930565 @default.
• W2000542328 cites W2108580170 @default.
• W2000542328 cites W2110015307 @default.
• W2000542328 cites W2110804359 @default.
• W2000542328 cites W2125691342 @default.
• W2000542328 cites W2128786355 @default.
• W2000542328 cites W2129759212 @default.
• W2000542328 cites W2131238404 @default.
• W2000542328 cites W2139697647 @default.
• W2000542328 cites W2147898515 @default.
• W2000542328 cites W2158434412 @default.
• W2000542328 doi "https://doi.org/10.1002/jcb.24431" @default.
• W2000542328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23097321" @default.
• W2000542328 hasPublicationYear "2013" @default.
• W2000542328 type Work @default.
• W2000542328 sameAs 2000542328 @default.
• W2000542328 citedByCount "11" @default.
• W2000542328 countsByYear W20005423282013 @default.
• W2000542328 countsByYear W20005423282014 @default.
• W2000542328 countsByYear W20005423282015 @default.
• W2000542328 countsByYear W20005423282016 @default.
• W2000542328 countsByYear W20005423282017 @default.
• W2000542328 countsByYear W20005423282018 @default.
• W2000542328 countsByYear W20005423282020 @default.
• W2000542328 crossrefType "journal-article" @default.
• W2000542328 hasAuthorship W2000542328A5016779636 @default.
• W2000542328 hasAuthorship W2000542328A5055245414 @default.
• W2000542328 hasAuthorship W2000542328A5063384634 @default.
• W2000542328 hasAuthorship W2000542328A5067331034 @default.
• W2000542328 hasConcept C104317684 @default.
• W2000542328 hasConcept C107459253 @default.
• W2000542328 hasConcept C109825262 @default.
• W2000542328 hasConcept C145103041 @default.
• W2000542328 hasConcept C1491633281 @default.
• W2000542328 hasConcept C153911025 @default.
• W2000542328 hasConcept C207168726 @default.
• W2000542328 hasConcept C207701140 @default.
• W2000542328 hasConcept C2777933648 @default.
• W2000542328 hasConcept C28328180 @default.
• W2000542328 hasConcept C54355233 @default.
• W2000542328 hasConcept C77255625 @default.
• W2000542328 hasConcept C86803240 @default.
• W2000542328 hasConcept C95444343 @default.
• W2000542328 hasConceptScore W2000542328C104317684 @default.
• W2000542328 hasConceptScore W2000542328C107459253 @default.
• W2000542328 hasConceptScore W2000542328C109825262 @default.
• W2000542328 hasConceptScore W2000542328C145103041 @default.
• W2000542328 hasConceptScore W2000542328C1491633281 @default.
• W2000542328 hasConceptScore W2000542328C153911025 @default.
• W2000542328 hasConceptScore W2000542328C207168726 @default.
• W2000542328 hasConceptScore W2000542328C207701140 @default.
• W2000542328 hasConceptScore W2000542328C2777933648 @default.
• W2000542328 hasConceptScore W2000542328C28328180 @default.
• W2000542328 hasConceptScore W2000542328C54355233 @default.
• W2000542328 hasConceptScore W2000542328C77255625 @default.
• W2000542328 hasConceptScore W2000542328C86803240 @default.
• W2000542328 hasConceptScore W2000542328C95444343 @default.
• W2000542328 hasIssue "4" @default.
• W2000542328 hasLocation W20005423281 @default.
• W2000542328 hasOpenAccess W2000542328 @default.
• W2000542328 hasPrimaryLocation W20005423281 @default.
• W2000542328 hasRelatedWork W1978560791 @default.
• W2000542328 hasRelatedWork W1990624462 @default.
• W2000542328 hasRelatedWork W1999541949 @default.
• W2000542328 hasRelatedWork W2011126334 @default.
• W2000542328 hasRelatedWork W2031687138 @default.

• next