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• W2000543257 abstract "To determine whether raised plasma glucose concentration independently influences outcome after acute stroke or is a stress response reflecting increased stroke severity.Long-term follow up study of patients admitted to an acute stroke unit.Western Infirmary, Glasgow.811 patients with acute stroke confirmed by computed tomography. Analysis was restricted to the 750 non-diabetic patients.Survival time and placement three months after stroke.645 patients (86%) had ischaemic stroke and 105 patients (14%) haemorrhagic stroke. Cox's proportional hazards modelling with stratification according to Oxfordshire Community Stroke Project categories identified increased age (relative hazard 1.36 per decade; 95% confidence interval 1.21 to 1.53), haemorrhagic stroke (relative hazard 1.67; 1.22 to 2.28), time to resolution of symptoms > 72 hours (relative hazard 2.15; 1.15 to 4.05), and hyperglycaemia (relative hazard 1.87; 1.43 to 2.45) as predictors of mortality. The effect of glucose concentration on survival was greatest in the first month.Plasma glucose concentration above 8 mmol/l after acute stroke predicts a poor prognosis after correcting for age, stroke severity, and stroke subtype. Raised plasma glucose concentration is therefore unlikely to be solely a stress response and should arguably be treated actively. A randomised trial is warranted." @default.
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• W2000543257 date "1997-05-03" @default.
• W2000543257 modified "2023-10-09" @default.
• W2000543257 title "Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long term follow up study" @default.
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• W2000543257 doi "https://doi.org/10.1136/bmj.314.7090.1303" @default.
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