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- W2000543339 abstract "Exposure of hamster amelanotic melanoma cells to L-dihydroxyphenylalanine (L-DOPA) resulted in a time dependent increase of cell pigmentation, tyrosinase concentration and activity with peak after 24 hours. Northern blot analysis showed a small but reproducible increase of tyrosinase mRNA after 3 hours and a decrease below the control level after 9 hours. After 24 and 48 hours tyrosinase mRNA was undetectable. It is suggested that L-DOPA or its oxidation products can stimulate intracellular tyrosinase concentration and regulate tyrosinase mRNA level both in positive and negative fashion." @default.
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- W2000543339 title "Molecular mechanism of tyrosinase regulation by L-DOPA in hamster melanoma cells" @default.
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- W2000543339 doi "https://doi.org/10.1016/0024-3205(91)90164-7" @default.
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