Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000550088> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2000550088 endingPage "2567" @default.
- W2000550088 startingPage "2561" @default.
- W2000550088 abstract "Dose-effect curves were obtained for five specific components of stereotyped behavior (locomotor hyperactivity, rearing, sniffing, grooming and oral activity) elicited by the non-selective dopamine agonists N-propylnorapomorphine (NPA; 0.001–4.5 mg/kg) and apomorphine (APO; 0.3–10.0 mg/kg), the selective D2 agonists LY 171555 (0.1–18.0 mg/kg) and RU 24213 (0.7–20.0 mg/kg) and the selective D1 agonist SKF 38393 (0.6–40.0 mg/kg) in male Sprague-Dawley rats. All the agonists except SKF 38393 elicited dose-dependent sniffing. Both NPA and APO produced robust oral activity at high doses, with concomitant reductions in other behaviors. Neither RU 24213 nor SKF 38393 elicited dose-dependent oral behavior, whereas LY 171555 induced a maximal level of oral activity which was much less intense than that produced by NPA or APO. SKF 38393 alone induced only dose-dependent grooming. Co-treatment of Sprague-Dawley rats with SKF 38393 (5–40 mg/kg) and either LY 171555 (0.1–1.6 mg/kg) or RU 24213 (6.7 mg/kg) produced significant enhancement of sniffing but not of oral activity. Significant enhancement of both behavioral components was observed in male Wistar rats. Differences in specific components of behavioral response on treatment with combinations of D1 and D2 agonists may reflect use of animal strains with different ratios of D1D2 innervation and/or different behavioral criteria." @default.
- W2000550088 created "2016-06-24" @default.
- W2000550088 creator A5018448753 @default.
- W2000550088 creator A5050180649 @default.
- W2000550088 creator A5079755833 @default.
- W2000550088 date "1988-01-01" @default.
- W2000550088 modified "2023-10-03" @default.
- W2000550088 title "Enhancement by the D1 dopamine agonist SKF 38393 of specific components of stereotypy elicited by the D2 agonists LY 171555 and RU 24213" @default.
- W2000550088 cites W1581666194 @default.
- W2000550088 cites W1965705220 @default.
- W2000550088 cites W1966308411 @default.
- W2000550088 cites W1981988180 @default.
- W2000550088 cites W1982176417 @default.
- W2000550088 cites W1991886920 @default.
- W2000550088 cites W1995851563 @default.
- W2000550088 cites W2004094484 @default.
- W2000550088 cites W2009579516 @default.
- W2000550088 cites W2010299478 @default.
- W2000550088 cites W2024342346 @default.
- W2000550088 cites W2051414078 @default.
- W2000550088 cites W2057788173 @default.
- W2000550088 cites W2076668541 @default.
- W2000550088 cites W2076968940 @default.
- W2000550088 cites W2079224121 @default.
- W2000550088 cites W2091813848 @default.
- W2000550088 doi "https://doi.org/10.1016/0024-3205(88)90324-4" @default.
- W2000550088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3260320" @default.
- W2000550088 hasPublicationYear "1988" @default.
- W2000550088 type Work @default.
- W2000550088 sameAs 2000550088 @default.
- W2000550088 citedByCount "37" @default.
- W2000550088 countsByYear W20005500882013 @default.
- W2000550088 countsByYear W20005500882020 @default.
- W2000550088 countsByYear W20005500882021 @default.
- W2000550088 crossrefType "journal-article" @default.
- W2000550088 hasAuthorship W2000550088A5018448753 @default.
- W2000550088 hasAuthorship W2000550088A5050180649 @default.
- W2000550088 hasAuthorship W2000550088A5079755833 @default.
- W2000550088 hasConcept C105702510 @default.
- W2000550088 hasConcept C126322002 @default.
- W2000550088 hasConcept C131722271 @default.
- W2000550088 hasConcept C134018914 @default.
- W2000550088 hasConcept C170493617 @default.
- W2000550088 hasConcept C185592680 @default.
- W2000550088 hasConcept C2777193897 @default.
- W2000550088 hasConcept C2777525119 @default.
- W2000550088 hasConcept C2778258207 @default.
- W2000550088 hasConcept C2778938600 @default.
- W2000550088 hasConcept C2779459141 @default.
- W2000550088 hasConcept C513476851 @default.
- W2000550088 hasConcept C55493867 @default.
- W2000550088 hasConcept C71924100 @default.
- W2000550088 hasConcept C98274493 @default.
- W2000550088 hasConceptScore W2000550088C105702510 @default.
- W2000550088 hasConceptScore W2000550088C126322002 @default.
- W2000550088 hasConceptScore W2000550088C131722271 @default.
- W2000550088 hasConceptScore W2000550088C134018914 @default.
- W2000550088 hasConceptScore W2000550088C170493617 @default.
- W2000550088 hasConceptScore W2000550088C185592680 @default.
- W2000550088 hasConceptScore W2000550088C2777193897 @default.
- W2000550088 hasConceptScore W2000550088C2777525119 @default.
- W2000550088 hasConceptScore W2000550088C2778258207 @default.
- W2000550088 hasConceptScore W2000550088C2778938600 @default.
- W2000550088 hasConceptScore W2000550088C2779459141 @default.
- W2000550088 hasConceptScore W2000550088C513476851 @default.
- W2000550088 hasConceptScore W2000550088C55493867 @default.
- W2000550088 hasConceptScore W2000550088C71924100 @default.
- W2000550088 hasConceptScore W2000550088C98274493 @default.
- W2000550088 hasIssue "25" @default.
- W2000550088 hasLocation W20005500881 @default.
- W2000550088 hasLocation W20005500882 @default.
- W2000550088 hasOpenAccess W2000550088 @default.
- W2000550088 hasPrimaryLocation W20005500881 @default.
- W2000550088 hasRelatedWork W12036348 @default.
- W2000550088 hasRelatedWork W1977930342 @default.
- W2000550088 hasRelatedWork W2013208056 @default.
- W2000550088 hasRelatedWork W2013689059 @default.
- W2000550088 hasRelatedWork W2015759942 @default.
- W2000550088 hasRelatedWork W2019790908 @default.
- W2000550088 hasRelatedWork W2048474481 @default.
- W2000550088 hasRelatedWork W2049016499 @default.
- W2000550088 hasRelatedWork W2073342311 @default.
- W2000550088 hasRelatedWork W2088840746 @default.
- W2000550088 hasVolume "42" @default.
- W2000550088 isParatext "false" @default.
- W2000550088 isRetracted "false" @default.
- W2000550088 magId "2000550088" @default.
- W2000550088 workType "article" @default.