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• W2000552714 abstract "ISEE-0046 Background and Objectives: An Environmental and Occupational (E-O) Working Group has been created to advise on research priorities and develop the E-O component of the Ontario Health Study (OHS). In the next five years, 150,000 participants will be recruited into the OHS. Information from questionnaires, physical measures, biospecimens and individual and community level environmental data will be collected to identify and characterize occupational and environmental causes of cancer. Methods: The E-O Working Group met in January 2009 to discuss prioritization and selection of exposures and/or contaminants for measurement, to develop a proposal for an “Envirobank,” and to develop the E-O questionnaires that will be sent to participants 3 months after baseline data collection. Members were asked to recommend key contaminants or exposures that should be given immediate consideration for measurement in the OHS. Results: Priority exposures include: aflatoxins, brominated flame retardants, EMF, metals, PAHs, perchlorate, perfluorochemicals, pharmaceutical estrogens, NOx, phenols (nonylphenol, bisphenol-A), particulates, select pesticides, phthalates, radon, shift work, solvents, water chlorination byproducts, and WiFi exposures. House dust and drinking water were recommended as the most useful samples to collect for the Envirobank to provide information on priority contaminants. Also recommended was the storage of residual urine (not sent to the Biorepository) from spot urine samples collected at the OHS assessment centers. A proposal to include indoor radon monitoring in a pilot study of 1500 individuals from 3 communities is being developed with the Radiation Protection Bureau of Health Canada. The Environmental Exposures and Residential History questionnaire is under development using the priorities outlined above. The E-O group is also working with the newly established Occupational Cancer Research Center in Ontario in developing the Occupational History and Exposures Questionnaire. Conclusions: The OHS presents a unique opportunity to collect environmental and occupational exposure data and provide more detailed information on absorbed dose for a population-based prospective cohort." @default.
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• W2000552714 date "2009-11-01" @default.
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• W2000552714 title "An Update on the Research Activities of the Environmental and Occupational Working Group for the Ontario Health Study (OHS)" @default.
• W2000552714 doi "https://doi.org/10.1097/01.ede.0000363020.36557.9c" @default.
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