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• W2000553889 abstract "Pseudo-symmetric HIV-1 protease inhibitors containing a novel HMC-hydrazide isostere as the transition-state mimic were designed and synthesized. Most of the synthetic compounds with varied structures at the P and P′ sites around this core unit showed potent inhibitory activity against HIV-1 protease with nanomolar Ki values." @default.
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• W2000553889 date "2003-01-01" @default.
• W2000553889 modified "2023-09-28" @default.
• W2000553889 title "Design and synthesis of pseudo-Symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-Hydrazide isostere" @default.
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• W2000553889 doi "https://doi.org/10.1016/s0960-894x(02)00848-x" @default.
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