FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000556721> ?p ?o ?g. }

• W2000556721 endingPage "240" @default.
• W2000556721 startingPage "236" @default.
• W2000556721 abstract "Background The cost of new anti-cancer drugs has dramatically increased in recent years, and countermeasures are required in order to limit pharmaceutical expenses. Sponsored clinical trials that provide drugs free of charge may be a useful tool in order to reduce drug costs. The aim of this analysis is to evaluate the effect of clinical trials on pharmaceutical expenditure savings. Methods We evaluated the cost of drugs administered in clinical practice and in clinical trials (considering only the standard regimens that were administered also in clinical practice) in 2010 at the Lung Cancer Unit of the National Institute for Cancer Research in Genoa, Italy. The cost of drugs was calculated on the price charged at our Institute in 2010. The supposed cost of experimental treatment replacing standard therapy was converted in the cost of the treatments that would have been chosen in clinical practice, considering histology, line of treatment and number of administered cycles. Results From 1/1/2010 to 12/31/2010, 196 patients affected by lung cancer or pleural mesothelioma were treated. 152 patients (78%) received treatment in clinical practice or in non-sponsored trials (18 patients in 4 trials), while 44 (22%) were treated in one of the 12 sponsored clinical trials recruiting in 2010. Globally, 606 cycles of treatment would have been administered to patients, of which 436 (72%) were administered in clinical practice or in non-sponsored trials and 170 (28%) were administered in pharmaceutical company sponsored clinical trials. The overall cost of those anti-neoplastic drugs, based on the prices charged at our Institute in 2010, was €799 803. The cost of drugs administered in clinical practice or in non-sponsored trials was €556 649 (70%), whereas the cost of standard drugs administered in clinical trials was €243 154 (30%). The grants provided by pharmaceutical companies were evaluated and amounted to €235 965. Conclusions The participation in sponsored clinical trials in which drugs are provided free of charge offers substantial cost savings for the National Health Service; moreover, the grants received for each enrolled patient produced additional income." @default.
• W2000556721 created "2016-06-24" @default.
• W2000556721 creator A5001753228 @default.
• W2000556721 creator A5005305678 @default.
• W2000556721 creator A5014619302 @default.
• W2000556721 creator A5024860874 @default.
• W2000556721 creator A5032477448 @default.
• W2000556721 creator A5035375963 @default.
• W2000556721 creator A5036706220 @default.
• W2000556721 creator A5039478541 @default.
• W2000556721 creator A5043174098 @default.
• W2000556721 creator A5077134511 @default.
• W2000556721 creator A5080816334 @default.
• W2000556721 creator A5085786637 @default.
• W2000556721 creator A5086247944 @default.
• W2000556721 date "2013-08-01" @default.
• W2000556721 modified "2023-10-18" @default.
• W2000556721 title "Free drugs in clinical trials and their potential cost saving impact on the National Health Service: A retrospective cost analysis in Italy" @default.
• W2000556721 cites W1980177098 @default.
• W2000556721 cites W2050056063 @default.
• W2000556721 cites W2059955004 @default.
• W2000556721 cites W2065540447 @default.
• W2000556721 cites W2170915815 @default.
• W2000556721 doi "https://doi.org/10.1016/j.lungcan.2013.03.021" @default.
• W2000556721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23648072" @default.
• W2000556721 hasPublicationYear "2013" @default.
• W2000556721 type Work @default.
• W2000556721 sameAs 2000556721 @default.
• W2000556721 citedByCount "20" @default.
• W2000556721 countsByYear W20005567212014 @default.
• W2000556721 countsByYear W20005567212015 @default.
• W2000556721 countsByYear W20005567212017 @default.
• W2000556721 countsByYear W20005567212018 @default.
• W2000556721 countsByYear W20005567212019 @default.
• W2000556721 countsByYear W20005567212020 @default.
• W2000556721 countsByYear W20005567212021 @default.
• W2000556721 countsByYear W20005567212022 @default.
• W2000556721 countsByYear W20005567212023 @default.
• W2000556721 crossrefType "journal-article" @default.
• W2000556721 hasAuthorship W2000556721A5001753228 @default.
• W2000556721 hasAuthorship W2000556721A5005305678 @default.
• W2000556721 hasAuthorship W2000556721A5014619302 @default.
• W2000556721 hasAuthorship W2000556721A5024860874 @default.
• W2000556721 hasAuthorship W2000556721A5032477448 @default.
• W2000556721 hasAuthorship W2000556721A5035375963 @default.
• W2000556721 hasAuthorship W2000556721A5036706220 @default.
• W2000556721 hasAuthorship W2000556721A5039478541 @default.
• W2000556721 hasAuthorship W2000556721A5043174098 @default.
• W2000556721 hasAuthorship W2000556721A5077134511 @default.
• W2000556721 hasAuthorship W2000556721A5080816334 @default.
• W2000556721 hasAuthorship W2000556721A5085786637 @default.
• W2000556721 hasAuthorship W2000556721A5086247944 @default.
• W2000556721 hasConcept C121608353 @default.
• W2000556721 hasConcept C126322002 @default.
• W2000556721 hasConcept C142724271 @default.
• W2000556721 hasConcept C177713679 @default.
• W2000556721 hasConcept C2776256026 @default.
• W2000556721 hasConcept C2777407522 @default.
• W2000556721 hasConcept C2779974597 @default.
• W2000556721 hasConcept C2780035454 @default.
• W2000556721 hasConcept C512399662 @default.
• W2000556721 hasConcept C535046627 @default.
• W2000556721 hasConcept C71924100 @default.
• W2000556721 hasConcept C98274493 @default.
• W2000556721 hasConceptScore W2000556721C121608353 @default.
• W2000556721 hasConceptScore W2000556721C126322002 @default.
• W2000556721 hasConceptScore W2000556721C142724271 @default.
• W2000556721 hasConceptScore W2000556721C177713679 @default.
• W2000556721 hasConceptScore W2000556721C2776256026 @default.
• W2000556721 hasConceptScore W2000556721C2777407522 @default.
• W2000556721 hasConceptScore W2000556721C2779974597 @default.
• W2000556721 hasConceptScore W2000556721C2780035454 @default.
• W2000556721 hasConceptScore W2000556721C512399662 @default.
• W2000556721 hasConceptScore W2000556721C535046627 @default.
• W2000556721 hasConceptScore W2000556721C71924100 @default.
• W2000556721 hasConceptScore W2000556721C98274493 @default.
• W2000556721 hasIssue "2" @default.
• W2000556721 hasLocation W20005567211 @default.
• W2000556721 hasLocation W20005567212 @default.
• W2000556721 hasOpenAccess W2000556721 @default.
• W2000556721 hasPrimaryLocation W20005567211 @default.
• W2000556721 hasRelatedWork W1967103478 @default.
• W2000556721 hasRelatedWork W2008597548 @default.
• W2000556721 hasRelatedWork W2032912323 @default.
• W2000556721 hasRelatedWork W2081773521 @default.
• W2000556721 hasRelatedWork W2372561159 @default.
• W2000556721 hasRelatedWork W2375344515 @default.
• W2000556721 hasRelatedWork W2390152934 @default.
• W2000556721 hasRelatedWork W3190750342 @default.
• W2000556721 hasRelatedWork W4254712629 @default.
• W2000556721 hasRelatedWork W4283018579 @default.
• W2000556721 hasVolume "81" @default.
• W2000556721 isParatext "false" @default.
• W2000556721 isRetracted "false" @default.
• W2000556721 magId "2000556721" @default.
• W2000556721 workType "article" @default.