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• W2000558233 abstract "Purpose: To assess the diagnostic performance of superparamagnetic iron oxide MR (SPIO-MR) imaging compared with double-phase spiral CT in detecting liver metastases and hepatocellular carcinoma. Material and Methods: Thirty-eight patients with a total of 144 malignant lesions of the liver were examined by CT and SPIO-MR. After definition of a gold standard by a panel of experts, the patient images were randomized and presented to a blinded jury of 5 independent observers whose task was to identify as many lesions as possible. the results were tested for statistical significance using multifactorial analysis of variance (α=5%). Results: SPIO-MR produced the highest detection rate and was significantly superior ( p<0.05) to unenhanced MR imaging and double spiral-phase contrast-enhanced CT (DPS-CECT). Maximum performance in DPS-CECT was obtained during the portal venous contrast phase but was significantly inferior to SPIO-MR imaging. the scores for unenhanced CT and unenhanced MR were significantly lower than for the corresponding enhanced procedures. SPIO-MR imaging produced a higher incidence of false-positive findings (n=39). Conclusion: SPIO-MR produced a significantly better detection rate for malignant focal liver lesions compared with double-phase spiral DPS-CECT but was associated with a higher rate of false-positive findings." @default.
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• W2000558233 date "1999-11-01" @default.
• W2000558233 modified "2023-10-16" @default.
• W2000558233 title "Spio-MR Imaging versus Double-Phase Spiral CT in Detecting Malignant Lesions of the Liver" @default.
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• W2000558233 doi "https://doi.org/10.3109/02841859909175600" @default.
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