FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000562447> ?p ?o ?g. }

• W2000562447 endingPage "253" @default.
• W2000562447 startingPage "237" @default.
• W2000562447 abstract "Recent reported outbreaks of Clostridium difficile-associated disease in Canada have changed the profile of C difficile infections. Historically, C difficile disease was thought of mainly as a nosocomial disease associated with broad-spectrum antibiotics, and the disease was usually not life threatening. The emergence of an epidemic strain, BI/NAP1/027, which produces a binary toxin in addition to the 2 classic C difficile toxins A and B and is resistant to some fluoroquinolones, was associated with large numbers of cases with high rates of mortality. Recently, C difficile has been reported more frequently in nonhospital-based settings, such as community-acquired cases. The C difficile disease is also being reported in populations once considered of low risk (children and young healthy women). In addition, poor response to metronidazole treatment is increasing. Faced with an increasing incidence of C difficile infections and the changing profile of patients who become infected, this paper will reexamine the current concepts on the epidemiology and treatment of C difficile-associated disease, present new hypotheses for risk factors, examine the role of spores in the transmission of C difficile, and provide recommendations that may enhance infection control practices. Recent reported outbreaks of Clostridium difficile-associated disease in Canada have changed the profile of C difficile infections. Historically, C difficile disease was thought of mainly as a nosocomial disease associated with broad-spectrum antibiotics, and the disease was usually not life threatening. The emergence of an epidemic strain, BI/NAP1/027, which produces a binary toxin in addition to the 2 classic C difficile toxins A and B and is resistant to some fluoroquinolones, was associated with large numbers of cases with high rates of mortality. Recently, C difficile has been reported more frequently in nonhospital-based settings, such as community-acquired cases. The C difficile disease is also being reported in populations once considered of low risk (children and young healthy women). In addition, poor response to metronidazole treatment is increasing. Faced with an increasing incidence of C difficile infections and the changing profile of patients who become infected, this paper will reexamine the current concepts on the epidemiology and treatment of C difficile-associated disease, present new hypotheses for risk factors, examine the role of spores in the transmission of C difficile, and provide recommendations that may enhance infection control practices." @default.
• W2000562447 created "2016-06-24" @default.
• W2000562447 creator A5001521760 @default.
• W2000562447 creator A5018454327 @default.
• W2000562447 creator A5022039779 @default.
• W2000562447 creator A5072424077 @default.
• W2000562447 date "2007-05-01" @default.
• W2000562447 modified "2023-10-11" @default.
• W2000562447 title "Implications of the changing face of Clostridium difficile disease for health care practitioners" @default.
• W2000562447 cites W104442755 @default.
• W2000562447 cites W1592163973 @default.
• W2000562447 cites W1619012111 @default.
• W2000562447 cites W1808786571 @default.
• W2000562447 cites W1919154593 @default.
• W2000562447 cites W1964548259 @default.
• W2000562447 cites W1965315529 @default.
• W2000562447 cites W1968780219 @default.
• W2000562447 cites W1970399600 @default.
• W2000562447 cites W1971477136 @default.
• W2000562447 cites W1973858868 @default.
• W2000562447 cites W1974640328 @default.
• W2000562447 cites W1974886846 @default.
• W2000562447 cites W1976630743 @default.
• W2000562447 cites W1977202107 @default.
• W2000562447 cites W1985064297 @default.
• W2000562447 cites W1985297718 @default.
• W2000562447 cites W1989355067 @default.
• W2000562447 cites W1991522354 @default.
• W2000562447 cites W1992411001 @default.
• W2000562447 cites W1993672395 @default.
• W2000562447 cites W1994090985 @default.
• W2000562447 cites W1999644200 @default.
• W2000562447 cites W2000815154 @default.
• W2000562447 cites W2001116525 @default.
• W2000562447 cites W2005821353 @default.
• W2000562447 cites W2006502123 @default.
• W2000562447 cites W2007060362 @default.
• W2000562447 cites W2008574151 @default.
• W2000562447 cites W2012553521 @default.
• W2000562447 cites W2012971498 @default.
• W2000562447 cites W2013868973 @default.
• W2000562447 cites W2015852070 @default.
• W2000562447 cites W2016313746 @default.
• W2000562447 cites W2016582138 @default.
• W2000562447 cites W2017665239 @default.
• W2000562447 cites W2023323558 @default.
• W2000562447 cites W2025473925 @default.
• W2000562447 cites W2026323570 @default.
• W2000562447 cites W2031525044 @default.
• W2000562447 cites W2031541246 @default.
• W2000562447 cites W2033407048 @default.
• W2000562447 cites W2034545414 @default.
• W2000562447 cites W2034660854 @default.
• W2000562447 cites W2038850449 @default.
• W2000562447 cites W2039483225 @default.
• W2000562447 cites W2041613596 @default.
• W2000562447 cites W2043188903 @default.
• W2000562447 cites W2044329617 @default.
• W2000562447 cites W2045022933 @default.
• W2000562447 cites W2045687412 @default.
• W2000562447 cites W2048532511 @default.
• W2000562447 cites W2053287071 @default.
• W2000562447 cites W2055363579 @default.
• W2000562447 cites W2056233231 @default.
• W2000562447 cites W2056270848 @default.
• W2000562447 cites W2056380416 @default.
• W2000562447 cites W2065780236 @default.
• W2000562447 cites W2066494092 @default.
• W2000562447 cites W2067250990 @default.
• W2000562447 cites W2068391765 @default.
• W2000562447 cites W2071830631 @default.
• W2000562447 cites W2072651990 @default.
• W2000562447 cites W2078239604 @default.
• W2000562447 cites W2078893988 @default.
• W2000562447 cites W2079516347 @default.
• W2000562447 cites W2082410001 @default.
• W2000562447 cites W2083941290 @default.
• W2000562447 cites W2085701252 @default.
• W2000562447 cites W2092135299 @default.
• W2000562447 cites W2096156780 @default.
• W2000562447 cites W2097341466 @default.
• W2000562447 cites W2097514777 @default.
• W2000562447 cites W2098223604 @default.
• W2000562447 cites W2098525180 @default.
• W2000562447 cites W2098587393 @default.
• W2000562447 cites W2100344755 @default.
• W2000562447 cites W2100938352 @default.
• W2000562447 cites W2101233913 @default.
• W2000562447 cites W2101790605 @default.
• W2000562447 cites W2102542037 @default.
• W2000562447 cites W2102779401 @default.
• W2000562447 cites W2104518766 @default.
• W2000562447 cites W2104996610 @default.
• W2000562447 cites W2105268765 @default.
• W2000562447 cites W2106583741 @default.
• W2000562447 cites W2107295643 @default.
• W2000562447 cites W2107470691 @default.
• W2000562447 cites W2108659548 @default.

• next