Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000565605> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2000565605 endingPage "580" @default.
- W2000565605 startingPage "577" @default.
- W2000565605 abstract "We demonstrate for the first time the appearance of acyclovir resistance in serial varicella zoster isolates from a patient treated with acyclovir. We recovered varicella zoster virus three times over a period of 5 months from the skin lesions of this patient with AIDS who was treated with three courses of intravenous acyclovir and prolonged low-dose oral acyclovir. The isolate recovered from a typical zoster lesion before acyclovir, and one obtained from a hyperkeratotic lesion 2 months later, after intravenous and oral acyclovir, were sensitive to acyclovir and produced normal amounts of thymidine kinase. In contrast, virus recovered from lesions 5 months after the onset, when the patient had received repeated courses of acyclovir, was acyclovir-resistant and thymidine-kinase-deficient. Resistance to acyclovir was associated with persistence of lesions which failed to improve with intravenous acyclovir, but was not associated with new lesion formation." @default.
- W2000565605 created "2016-06-24" @default.
- W2000565605 creator A5005114252 @default.
- W2000565605 creator A5027712301 @default.
- W2000565605 creator A5038217140 @default.
- W2000565605 creator A5081359857 @default.
- W2000565605 date "1990-06-01" @default.
- W2000565605 modified "2023-10-16" @default.
- W2000565605 title "Emergence of acyclovir-resistant varicella zoster virus in an AIDS patient on prolonged acyclovir therapy" @default.
- W2000565605 doi "https://doi.org/10.1097/00002030-199006000-00014" @default.
- W2000565605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2167103" @default.
- W2000565605 hasPublicationYear "1990" @default.
- W2000565605 type Work @default.
- W2000565605 sameAs 2000565605 @default.
- W2000565605 citedByCount "99" @default.
- W2000565605 countsByYear W20005656052012 @default.
- W2000565605 countsByYear W20005656052014 @default.
- W2000565605 countsByYear W20005656052015 @default.
- W2000565605 countsByYear W20005656052017 @default.
- W2000565605 countsByYear W20005656052018 @default.
- W2000565605 countsByYear W20005656052019 @default.
- W2000565605 countsByYear W20005656052021 @default.
- W2000565605 countsByYear W20005656052022 @default.
- W2000565605 crossrefType "journal-article" @default.
- W2000565605 hasAuthorship W2000565605A5005114252 @default.
- W2000565605 hasAuthorship W2000565605A5027712301 @default.
- W2000565605 hasAuthorship W2000565605A5038217140 @default.
- W2000565605 hasAuthorship W2000565605A5081359857 @default.
- W2000565605 hasConcept C141071460 @default.
- W2000565605 hasConcept C159047783 @default.
- W2000565605 hasConcept C16005928 @default.
- W2000565605 hasConcept C2522874641 @default.
- W2000565605 hasConcept C2776147627 @default.
- W2000565605 hasConcept C2776159415 @default.
- W2000565605 hasConcept C2776409557 @default.
- W2000565605 hasConcept C2779450786 @default.
- W2000565605 hasConcept C2780727368 @default.
- W2000565605 hasConcept C2781156865 @default.
- W2000565605 hasConcept C2781196997 @default.
- W2000565605 hasConcept C71924100 @default.
- W2000565605 hasConceptScore W2000565605C141071460 @default.
- W2000565605 hasConceptScore W2000565605C159047783 @default.
- W2000565605 hasConceptScore W2000565605C16005928 @default.
- W2000565605 hasConceptScore W2000565605C2522874641 @default.
- W2000565605 hasConceptScore W2000565605C2776147627 @default.
- W2000565605 hasConceptScore W2000565605C2776159415 @default.
- W2000565605 hasConceptScore W2000565605C2776409557 @default.
- W2000565605 hasConceptScore W2000565605C2779450786 @default.
- W2000565605 hasConceptScore W2000565605C2780727368 @default.
- W2000565605 hasConceptScore W2000565605C2781156865 @default.
- W2000565605 hasConceptScore W2000565605C2781196997 @default.
- W2000565605 hasConceptScore W2000565605C71924100 @default.
- W2000565605 hasIssue "6" @default.
- W2000565605 hasLocation W20005656051 @default.
- W2000565605 hasLocation W20005656052 @default.
- W2000565605 hasOpenAccess W2000565605 @default.
- W2000565605 hasPrimaryLocation W20005656051 @default.
- W2000565605 hasRelatedWork W1846954693 @default.
- W2000565605 hasRelatedWork W1972241043 @default.
- W2000565605 hasRelatedWork W1992941574 @default.
- W2000565605 hasRelatedWork W1994326559 @default.
- W2000565605 hasRelatedWork W2000565605 @default.
- W2000565605 hasRelatedWork W2038801503 @default.
- W2000565605 hasRelatedWork W2039677112 @default.
- W2000565605 hasRelatedWork W2102565620 @default.
- W2000565605 hasRelatedWork W2153434009 @default.
- W2000565605 hasRelatedWork W2162468440 @default.
- W2000565605 hasVolume "4" @default.
- W2000565605 isParatext "false" @default.
- W2000565605 isRetracted "false" @default.
- W2000565605 magId "2000565605" @default.
- W2000565605 workType "article" @default.