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• W2000569198 abstract "New and upcoming vaccines provide protection against types 16 and 18 of human papillomavirus (HPV), which are responsible for an estimated 70% of all cervical cancers. One vaccine also protects against HPV types 6 and 11, which cause more than 90% of genital warts. We use a mathematical model of HPV transmission and immunity to explore the effect of vaccination on the evolution of HPV types. If vaccination provides cross-immunity at least equal to that of natural infection, it may contract the niche space available to other HPV types a million-fold. If natural infection provides greater cross-immunity than vaccination, vaccination may expand available niche space up to 470-fold. The balance of epidemiologic data suggests vaccination will reduce the available niche space." @default.
• W2000569198 created "2016-06-24" @default.
• W2000569198 creator A5003588465 @default.
• W2000569198 creator A5023984726 @default.
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• W2000569198 date "2008-07-01" @default.
• W2000569198 modified "2023-09-23" @default.
• W2000569198 title "Vaccination and the evolutionary ecology of human papillomavirus" @default.
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• W2000569198 doi "https://doi.org/10.1016/j.vaccine.2008.04.010" @default.
• W2000569198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18773535" @default.
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