FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000569912> ?p ?o ?g. }

• W2000569912 endingPage "137" @default.
• W2000569912 startingPage "127" @default.
• W2000569912 abstract "Fibronectin type III domain-containing 5 protein (Fndc5) is an exercise hormone and its transcript profile in mouse showed high degree of expression in heart, skeletal muscle and brain. Our previous studies indicated a significant increase (approximately 10 fold) in mRNA level of Fndc5 when embryonic stem cells were differentiated into beating bodies. As a step closer to identify the involvement of Fndc5 in the process of cardiomyocyte differentiation, we generated a stably inducible transduced mouse embryonic stem cell (mESC) line that overexpressed Fndc5 following Doxycycline induction. Our results indicated that the overexpression of Fndc5 during spontaneous cardiac differentiation significantly increased not only at RNA levels for mesodermal markers but also at the transcriptional levels for cardiac progenitor and cardiac genes. These data suggest that Fndc5 may be involved in cardiomyocyte differentiation. Therefore, a new hope will be arisen for potential application of this myokine for regeneration of damaged cardiac tissues especially in cardiac failure." @default.
• W2000569912 created "2016-06-24" @default.
• W2000569912 creator A5006233759 @default.
• W2000569912 creator A5019924570 @default.
• W2000569912 creator A5032370980 @default.
• W2000569912 creator A5044318757 @default.
• W2000569912 creator A5045958617 @default.
• W2000569912 creator A5051798464 @default.
• W2000569912 creator A5064583112 @default.
• W2000569912 creator A5091186278 @default.
• W2000569912 date "2014-11-01" @default.
• W2000569912 modified "2023-09-25" @default.
• W2000569912 title "Induced expression of Fndc5 significantly increased cardiomyocyte differentiation rate of mouse embryonic stem cells" @default.
• W2000569912 cites W1984787606 @default.
• W2000569912 cites W1992521991 @default.
• W2000569912 cites W2009761723 @default.
• W2000569912 cites W2014201708 @default.
• W2000569912 cites W2049208901 @default.
• W2000569912 cites W2076975132 @default.
• W2000569912 cites W2085397620 @default.
• W2000569912 cites W2085647104 @default.
• W2000569912 cites W2119206501 @default.
• W2000569912 cites W2124205424 @default.
• W2000569912 cites W2134384360 @default.
• W2000569912 cites W2146923102 @default.
• W2000569912 cites W2159745709 @default.
• W2000569912 cites W2167344369 @default.
• W2000569912 cites W2466811260 @default.
• W2000569912 doi "https://doi.org/10.1016/j.gene.2014.08.045" @default.
• W2000569912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25168892" @default.
• W2000569912 hasPublicationYear "2014" @default.
• W2000569912 type Work @default.
• W2000569912 sameAs 2000569912 @default.
• W2000569912 citedByCount "27" @default.
• W2000569912 countsByYear W20005699122015 @default.
• W2000569912 countsByYear W20005699122016 @default.
• W2000569912 countsByYear W20005699122017 @default.
• W2000569912 countsByYear W20005699122018 @default.
• W2000569912 countsByYear W20005699122019 @default.
• W2000569912 countsByYear W20005699122020 @default.
• W2000569912 countsByYear W20005699122021 @default.
• W2000569912 crossrefType "journal-article" @default.
• W2000569912 hasAuthorship W2000569912A5006233759 @default.
• W2000569912 hasAuthorship W2000569912A5019924570 @default.
• W2000569912 hasAuthorship W2000569912A5032370980 @default.
• W2000569912 hasAuthorship W2000569912A5044318757 @default.
• W2000569912 hasAuthorship W2000569912A5045958617 @default.
• W2000569912 hasAuthorship W2000569912A5051798464 @default.
• W2000569912 hasAuthorship W2000569912A5064583112 @default.
• W2000569912 hasAuthorship W2000569912A5091186278 @default.
• W2000569912 hasConcept C104317684 @default.
• W2000569912 hasConcept C107459253 @default.
• W2000569912 hasConcept C117365660 @default.
• W2000569912 hasConcept C126322002 @default.
• W2000569912 hasConcept C134018914 @default.
• W2000569912 hasConcept C145103041 @default.
• W2000569912 hasConcept C148738053 @default.
• W2000569912 hasConcept C153911025 @default.
• W2000569912 hasConcept C189165786 @default.
• W2000569912 hasConcept C201750760 @default.
• W2000569912 hasConcept C206810289 @default.
• W2000569912 hasConcept C207200792 @default.
• W2000569912 hasConcept C207701140 @default.
• W2000569912 hasConcept C2779959927 @default.
• W2000569912 hasConcept C28328180 @default.
• W2000569912 hasConcept C54355233 @default.
• W2000569912 hasConcept C71924100 @default.
• W2000569912 hasConcept C86492073 @default.
• W2000569912 hasConcept C86803240 @default.
• W2000569912 hasConcept C95444343 @default.
• W2000569912 hasConceptScore W2000569912C104317684 @default.
• W2000569912 hasConceptScore W2000569912C107459253 @default.
• W2000569912 hasConceptScore W2000569912C117365660 @default.
• W2000569912 hasConceptScore W2000569912C126322002 @default.
• W2000569912 hasConceptScore W2000569912C134018914 @default.
• W2000569912 hasConceptScore W2000569912C145103041 @default.
• W2000569912 hasConceptScore W2000569912C148738053 @default.
• W2000569912 hasConceptScore W2000569912C153911025 @default.
• W2000569912 hasConceptScore W2000569912C189165786 @default.
• W2000569912 hasConceptScore W2000569912C201750760 @default.
• W2000569912 hasConceptScore W2000569912C206810289 @default.
• W2000569912 hasConceptScore W2000569912C207200792 @default.
• W2000569912 hasConceptScore W2000569912C207701140 @default.
• W2000569912 hasConceptScore W2000569912C2779959927 @default.
• W2000569912 hasConceptScore W2000569912C28328180 @default.
• W2000569912 hasConceptScore W2000569912C54355233 @default.
• W2000569912 hasConceptScore W2000569912C71924100 @default.
• W2000569912 hasConceptScore W2000569912C86492073 @default.
• W2000569912 hasConceptScore W2000569912C86803240 @default.
• W2000569912 hasConceptScore W2000569912C95444343 @default.
• W2000569912 hasFunder F4320322998 @default.
• W2000569912 hasIssue "2" @default.
• W2000569912 hasLocation W20005699121 @default.
• W2000569912 hasLocation W20005699122 @default.
• W2000569912 hasOpenAccess W2000569912 @default.
• W2000569912 hasPrimaryLocation W20005699121 @default.
• W2000569912 hasRelatedWork W1818635750 @default.
• W2000569912 hasRelatedWork W2009519731 @default.

• next