FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000570402> ?p ?o ?g. }

• W2000570402 endingPage "27" @default.
• W2000570402 startingPage "15" @default.
• W2000570402 abstract "Restorative proctocolectomy (RPC) with or without mucosectomy is the treatment of choice for most patients with ulcerative colitis (UC) requiring surgery. The ileal mucosa in the reservoir and the anorectal columnar epithelium below the ileo-anal anastomosis are at risk of neoplastic transformation.The literature has been reviewed to identify patients developing this complication and an attempt has been made to develop a rational follow-up policy based on the data available.Dysplasia in the ileal reservoir is rare. It is associated with histological type C changes, sclerosing cholangitis and unremitting pouchitis in the ileal mucosa and to the presence of sclerosing cholangitis. Nine patients who have developed adenocarcinoma in the residual anorectal mucosa and seven in the reservoir have been reported in the literature. A further hitherto unreported patient treated by the authors brings the total to 17 patients. Twelve of these had histopathological data on either dysplasia or carcinoma in the original operative specimen. The time intervals from the onset of UC and from the RPC to the development of cancer were 120-528 (median 246) and 16-216 (median 60) months respectively. Cancer appeared to be related to the duration of disease rather than to the interval from RPC. In all the reported patients the interval from the onset of UC was 10 years.Based on these data a surveillance programme should begin at 10 years from the onset of disease. Patients with dysplasia or carcinoma in the original specimen, those with type C ileal mucosal changes and patients with sclerosing cholangitis should be selected for surveillance. This will involve multiple biopsies of the ileal reservoir and the anorectal mucosa below the ileo-anal anastomosis." @default.
• W2000570402 created "2016-06-24" @default.
• W2000570402 creator A5022137060 @default.
• W2000570402 creator A5024531043 @default.
• W2000570402 creator A5031998283 @default.
• W2000570402 creator A5076036301 @default.
• W2000570402 date "2006-12-06" @default.
• W2000570402 modified "2023-10-10" @default.
• W2000570402 title "Risk of dysplasia and adenocarcinoma following restorative proctocolectomy for ulcerative colitis" @default.
• W2000570402 cites W1521144418 @default.
• W2000570402 cites W1533325322 @default.
• W2000570402 cites W1555027006 @default.
• W2000570402 cites W1570526968 @default.
• W2000570402 cites W1612925887 @default.
• W2000570402 cites W1965499257 @default.
• W2000570402 cites W1966072699 @default.
• W2000570402 cites W1969067961 @default.
• W2000570402 cites W1969954064 @default.
• W2000570402 cites W1973165951 @default.
• W2000570402 cites W1973691341 @default.
• W2000570402 cites W1974480177 @default.
• W2000570402 cites W1974627648 @default.
• W2000570402 cites W1974694264 @default.
• W2000570402 cites W1976905783 @default.
• W2000570402 cites W1978885244 @default.
• W2000570402 cites W1984367287 @default.
• W2000570402 cites W1984645042 @default.
• W2000570402 cites W1989177546 @default.
• W2000570402 cites W1993169155 @default.
• W2000570402 cites W1996257748 @default.
• W2000570402 cites W1996467603 @default.
• W2000570402 cites W1997822058 @default.
• W2000570402 cites W1999601011 @default.
• W2000570402 cites W2001720082 @default.
• W2000570402 cites W2006797690 @default.
• W2000570402 cites W2007838388 @default.
• W2000570402 cites W2010101981 @default.
• W2000570402 cites W2013644344 @default.
• W2000570402 cites W2017235546 @default.
• W2000570402 cites W2020770427 @default.
• W2000570402 cites W2021003964 @default.
• W2000570402 cites W2023118376 @default.
• W2000570402 cites W2028646234 @default.
• W2000570402 cites W2028875662 @default.
• W2000570402 cites W2029637162 @default.
• W2000570402 cites W2029647085 @default.
• W2000570402 cites W2031647186 @default.
• W2000570402 cites W2035166596 @default.
• W2000570402 cites W2035383234 @default.
• W2000570402 cites W2035914362 @default.
• W2000570402 cites W2039024125 @default.
• W2000570402 cites W2039362722 @default.
• W2000570402 cites W2045377222 @default.
• W2000570402 cites W2046948168 @default.
• W2000570402 cites W2048186278 @default.
• W2000570402 cites W2048204343 @default.
• W2000570402 cites W2048318184 @default.
• W2000570402 cites W2048422337 @default.
• W2000570402 cites W2049940200 @default.
• W2000570402 cites W2052745451 @default.
• W2000570402 cites W2054139733 @default.
• W2000570402 cites W2055133409 @default.
• W2000570402 cites W2060109737 @default.
• W2000570402 cites W2065922866 @default.
• W2000570402 cites W2066410282 @default.
• W2000570402 cites W2067771756 @default.
• W2000570402 cites W2069616155 @default.
• W2000570402 cites W2070132270 @default.
• W2000570402 cites W2073699180 @default.
• W2000570402 cites W2078629579 @default.
• W2000570402 cites W2079318685 @default.
• W2000570402 cites W2085770868 @default.
• W2000570402 cites W2089792527 @default.
• W2000570402 cites W2090411733 @default.
• W2000570402 cites W2094609753 @default.
• W2000570402 cites W2096322844 @default.
• W2000570402 cites W2115205193 @default.
• W2000570402 cites W2128965682 @default.
• W2000570402 cites W2130568060 @default.
• W2000570402 cites W2159120383 @default.
• W2000570402 cites W2168045406 @default.
• W2000570402 cites W2169097280 @default.
• W2000570402 cites W2275648668 @default.
• W2000570402 cites W2316123995 @default.
• W2000570402 cites W2318755450 @default.
• W2000570402 cites W2320547972 @default.
• W2000570402 cites W2322200694 @default.
• W2000570402 cites W2324350900 @default.
• W2000570402 cites W2324680484 @default.
• W2000570402 cites W2333407256 @default.
• W2000570402 cites W2790146970 @default.
• W2000570402 cites W4252742165 @default.
• W2000570402 cites W91792756 @default.
• W2000570402 doi "https://doi.org/10.1111/j.1463-1318.2006.01148.x" @default.
• W2000570402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17181842" @default.
• W2000570402 hasPublicationYear "2006" @default.
• W2000570402 type Work @default.
• W2000570402 sameAs 2000570402 @default.

• next