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- W2000571522 endingPage "197" @default.
- W2000571522 startingPage "187" @default.
- W2000571522 abstract "Advances in the treatment of coronary artery disease have seen a significant drop in mortality and morbidity particularly amongst patients with acute myocardial infarction (MI). In particular, percutaneous trans-luminal balloon angioplasty (PTCA) with stenting to re-open atherosclerotic coronary arteries has yielded marked improvement in clinical outcome for patients with acute MI. Furthermore, with the advent of drug-eluting stents occurrence rates for coronary artery restenosis, one common clinical problem associated with angioplasty and stent deployment, have declined markedly. However, coronary restenosis in diabetic patients remains an on-going problem. The success of drug-eluting stents has seen a renewed focus on myocardial ischaemia reperfusion (IR) injury as this represents one area of research where many questions remain unanswered. In particular, the relationship between myocardial IR injury and decreased myocardial micro-vasculature re-flow post PTCA (that ultimately leads to poor clinical outcome and myocardial damage/dysfunction) is one area of research with the potential to decrease current complication rates further in patients suffering myocardial IR injury sustained during MI. This review discusses the role for oxidative stress, oxidant source(s) and both gene regulation and stem-cell therapy as potential strategic targets in the ischaemic myocardium, with the ultimate aim of providing significant cardioprotection in the setting of acute MI." @default.
- W2000571522 created "2016-06-24" @default.
- W2000571522 creator A5019945539 @default.
- W2000571522 creator A5045757605 @default.
- W2000571522 creator A5059558584 @default.
- W2000571522 creator A5060128303 @default.
- W2000571522 date "2005-08-01" @default.
- W2000571522 modified "2023-09-27" @default.
- W2000571522 title "Oxidative stress in myocardial ischaemia reperfusion injury: a renewed focus on a long-standing area of heart research" @default.
- W2000571522 cites W108926472 @default.
- W2000571522 cites W145648313 @default.
- W2000571522 cites W1506462561 @default.
- W2000571522 cites W1537192388 @default.
- W2000571522 cites W1541256063 @default.
- W2000571522 cites W1631250427 @default.
- W2000571522 cites W1754453110 @default.
- W2000571522 cites W1828125754 @default.
- W2000571522 cites W1963804628 @default.
- W2000571522 cites W1964037605 @default.
- W2000571522 cites W1964788971 @default.
- W2000571522 cites W1966410796 @default.
- W2000571522 cites W1966582616 @default.
- W2000571522 cites W1967548066 @default.
- W2000571522 cites W1970492129 @default.
- W2000571522 cites W1972465295 @default.
- W2000571522 cites W1973760359 @default.
- W2000571522 cites W1974047748 @default.
- W2000571522 cites W1974821362 @default.
- W2000571522 cites W1977062537 @default.
- W2000571522 cites W1977208217 @default.
- W2000571522 cites W1977437881 @default.
- W2000571522 cites W1982272449 @default.
- W2000571522 cites W1985148885 @default.
- W2000571522 cites W1989469748 @default.
- W2000571522 cites W1989507960 @default.
- W2000571522 cites W1990026901 @default.
- W2000571522 cites W1992904182 @default.
- W2000571522 cites W1994916925 @default.
- W2000571522 cites W2001439186 @default.
- W2000571522 cites W2001441572 @default.
- W2000571522 cites W2004222886 @default.
- W2000571522 cites W2006541820 @default.
- W2000571522 cites W2008998010 @default.
- W2000571522 cites W2010394923 @default.
- W2000571522 cites W2010439113 @default.
- W2000571522 cites W2011375069 @default.
- W2000571522 cites W2011425675 @default.
- W2000571522 cites W2016584191 @default.
- W2000571522 cites W2024206845 @default.
- W2000571522 cites W2026425756 @default.
- W2000571522 cites W2030319693 @default.
- W2000571522 cites W2036579170 @default.
- W2000571522 cites W2036602304 @default.
- W2000571522 cites W2037967237 @default.
- W2000571522 cites W2041480528 @default.
- W2000571522 cites W2045207523 @default.
- W2000571522 cites W2046628294 @default.
- W2000571522 cites W2047456088 @default.
- W2000571522 cites W2048408379 @default.
- W2000571522 cites W2051106508 @default.
- W2000571522 cites W2053838576 @default.
- W2000571522 cites W2056905507 @default.
- W2000571522 cites W2060300790 @default.
- W2000571522 cites W2061297953 @default.
- W2000571522 cites W2064891558 @default.
- W2000571522 cites W2066033241 @default.
- W2000571522 cites W2069435420 @default.
- W2000571522 cites W2071396416 @default.
- W2000571522 cites W2071560742 @default.
- W2000571522 cites W2075384300 @default.
- W2000571522 cites W2076386347 @default.
- W2000571522 cites W2078265076 @default.
- W2000571522 cites W2079380240 @default.
- W2000571522 cites W2081080034 @default.
- W2000571522 cites W2083630382 @default.
- W2000571522 cites W2084017708 @default.
- W2000571522 cites W2085500137 @default.
- W2000571522 cites W2085609942 @default.
- W2000571522 cites W2088873146 @default.
- W2000571522 cites W2092272253 @default.
- W2000571522 cites W2092836756 @default.
- W2000571522 cites W2093057466 @default.
- W2000571522 cites W2097744068 @default.
- W2000571522 cites W2101419974 @default.
- W2000571522 cites W2107994885 @default.
- W2000571522 cites W2114811479 @default.
- W2000571522 cites W2115914856 @default.
- W2000571522 cites W2121203285 @default.
- W2000571522 cites W2122634753 @default.
- W2000571522 cites W2122803476 @default.
- W2000571522 cites W2125155374 @default.
- W2000571522 cites W2127884424 @default.
- W2000571522 cites W2130052958 @default.
- W2000571522 cites W2136530061 @default.
- W2000571522 cites W2141844501 @default.
- W2000571522 cites W2146665526 @default.
- W2000571522 cites W2149301933 @default.
- W2000571522 cites W2150115812 @default.