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- W2000571837 abstract "Thalamic stimulation has emerged as an alternative to thalamotomy for the treatment of essential and Parkinson's disease tremor. Good tremor control is achieved in up to 83% of patients with Parkinson's disease and 59% of patients with essential tremor.1 Side effects include dysarthria (19.6%), paresthesias (9%), dysequilibrium (9%), and dystonia(9%).1 In addition, some patients experience a deterioration in tremor control over time.1 We report the case of a patient who developed tolerance and delayed stimulation-induced thalamic ataxia syndrome.Case report. A 64-year-old right-handed accountant had a 17-year history of essential tremor. He initially developed a postural tremor in the right hand. Tremor affected his left hand 5 years later and worsened bilaterally over time. During the last 6 years he experienced a head and voice tremor when anxious. He reported marked disability in activities of daily living, including extreme difficulty brushing his teeth, shaving, and feeding. Alcohol temporarily alleviated the tremor. His father and three brothers had a similar tremor. Mysoline was not effective, and beta blockers caused nausea and fatigue.Examination revealed tremor of the head and both upper extremities. He had a mild-amplitude, high-frequency head tremor, a mild-amplitude, high-frequency postural tremor of the left …" @default.
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- W2000571837 date "1998-04-01" @default.
- W2000571837 modified "2023-10-09" @default.
- W2000571837 title "Delayed stimulation-induced thalamic ataxia syndrome" @default.
- W2000571837 cites W2414262416 @default.
- W2000571837 doi "https://doi.org/10.1212/wnl.50.4.1184" @default.
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