FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000573877> ?p ?o ?g. }

• W2000573877 endingPage "399" @default.
• W2000573877 startingPage "391" @default.
• W2000573877 abstract "Ultrasound contrast agents are now available since a few years and used for diagnostic purposes. Improved diagnostic decisions have been made possible with new imaging methods that are mainly based on the nonlinear properties of gas microbubbles. Since it is well known that contrast agents are destroyed by ultrasound when the acoustic pressure exceeds a threshold, extremely low acoustic pressures were applied to achieve enhanced contrast image quality. However, destruction of contrast microbubbles is not necessarily undesirable, since it is beneficial in, for example, destruction/reperfusion imaging and recently in drug delivery. We investigate in this experimental study the destruction dynamics of a contrast agent consisting of nitrogen bubbles encapsulated in a double polymer/albumin wall shell. This is accomplished using an ultrafast camera Brandaris that operates at a frame rate of 25 MHz and records 128 frames. The measurements were performed with an ultrasound sine burst of 10 cycles at 1.7 MHz. Different acoustic pressures were applied and various microsphere sizes were examined. The results show three different zones depending on the applied pressure and bubble size: these are nondestruction zone, transient zone and destruction zone. The nondestruction zone is reached for either very small microspheres or low mechanical indices (MI) (<0.3). In the destruction zone lie either large microspheres (5 microm or higher) even when irradiated at low MIs or small microspheres (<5 microm) when the MI is above 0.6. The optical observations revealed that the destruction of the microspheres is characterized by shell rupture and gas release. The release of the gas gives rise to new free microbubble that lasts for a few milliseconds and then disappears due to dissolution. In the transient zone, the microspheres are mainly compressed in the first few cycles but no expansion is induced. After intense compressions, the shell fissures and gas escapes in the last cycles of the burst or during a second burst depending on the initial size and MI. These optical recordings are important to investigate contrast bubble destruction and can help in amplifying or minimizing this process. Indeed, bubble disruption remains the basis of most current sensitive methods for detecting perfusion with contrast agents and is an essential component of perfusion quantification with microbubbles, in addition to drug delivery applications and pressure measurements." @default.
• W2000573877 created "2016-06-24" @default.
• W2000573877 creator A5035697111 @default.
• W2000573877 creator A5043737347 @default.
• W2000573877 creator A5084703712 @default.
• W2000573877 date "2005-03-01" @default.
• W2000573877 modified "2023-10-18" @default.
• W2000573877 title "High-speed optical observations of contrast agent destruction" @default.
• W2000573877 cites W1991146807 @default.
• W2000573877 cites W1993509416 @default.
• W2000573877 cites W2005574389 @default.
• W2000573877 cites W2007413790 @default.
• W2000573877 cites W2026988376 @default.
• W2000573877 cites W2029646789 @default.
• W2000573877 cites W2033755360 @default.
• W2000573877 cites W2037253046 @default.
• W2000573877 cites W2055598761 @default.
• W2000573877 cites W2094309950 @default.
• W2000573877 cites W2125048739 @default.
• W2000573877 cites W2171646700 @default.
• W2000573877 cites W2319708035 @default.
• W2000573877 doi "https://doi.org/10.1016/j.ultrasmedbio.2004.12.004" @default.
• W2000573877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15749563" @default.
• W2000573877 hasPublicationYear "2005" @default.
• W2000573877 type Work @default.
• W2000573877 sameAs 2000573877 @default.
• W2000573877 citedByCount "173" @default.
• W2000573877 countsByYear W20005738772012 @default.
• W2000573877 countsByYear W20005738772013 @default.
• W2000573877 countsByYear W20005738772014 @default.
• W2000573877 countsByYear W20005738772015 @default.
• W2000573877 countsByYear W20005738772016 @default.
• W2000573877 countsByYear W20005738772017 @default.
• W2000573877 countsByYear W20005738772018 @default.
• W2000573877 countsByYear W20005738772019 @default.
• W2000573877 countsByYear W20005738772020 @default.
• W2000573877 countsByYear W20005738772021 @default.
• W2000573877 countsByYear W20005738772022 @default.
• W2000573877 countsByYear W20005738772023 @default.
• W2000573877 crossrefType "journal-article" @default.
• W2000573877 hasAuthorship W2000573877A5035697111 @default.
• W2000573877 hasAuthorship W2000573877A5043737347 @default.
• W2000573877 hasAuthorship W2000573877A5084703712 @default.
• W2000573877 hasBestOaLocation W20005738772 @default.
• W2000573877 hasConcept C120665830 @default.
• W2000573877 hasConcept C121332964 @default.
• W2000573877 hasConcept C127413603 @default.
• W2000573877 hasConcept C136229726 @default.
• W2000573877 hasConcept C143753070 @default.
• W2000573877 hasConcept C157915830 @default.
• W2000573877 hasConcept C189942447 @default.
• W2000573877 hasConcept C192562407 @default.
• W2000573877 hasConcept C24890656 @default.
• W2000573877 hasConcept C2776502983 @default.
• W2000573877 hasConcept C42360764 @default.
• W2000573877 hasConcept C57879066 @default.
• W2000573877 hasConcept C64012434 @default.
• W2000573877 hasConcept C71924100 @default.
• W2000573877 hasConceptScore W2000573877C120665830 @default.
• W2000573877 hasConceptScore W2000573877C121332964 @default.
• W2000573877 hasConceptScore W2000573877C127413603 @default.
• W2000573877 hasConceptScore W2000573877C136229726 @default.
• W2000573877 hasConceptScore W2000573877C143753070 @default.
• W2000573877 hasConceptScore W2000573877C157915830 @default.
• W2000573877 hasConceptScore W2000573877C189942447 @default.
• W2000573877 hasConceptScore W2000573877C192562407 @default.
• W2000573877 hasConceptScore W2000573877C24890656 @default.
• W2000573877 hasConceptScore W2000573877C2776502983 @default.
• W2000573877 hasConceptScore W2000573877C42360764 @default.
• W2000573877 hasConceptScore W2000573877C57879066 @default.
• W2000573877 hasConceptScore W2000573877C64012434 @default.
• W2000573877 hasConceptScore W2000573877C71924100 @default.
• W2000573877 hasIssue "3" @default.
• W2000573877 hasLocation W20005738771 @default.
• W2000573877 hasLocation W20005738772 @default.
• W2000573877 hasLocation W20005738773 @default.
• W2000573877 hasOpenAccess W2000573877 @default.
• W2000573877 hasPrimaryLocation W20005738771 @default.
• W2000573877 hasRelatedWork W1999683198 @default.
• W2000573877 hasRelatedWork W2003289253 @default.
• W2000573877 hasRelatedWork W2036898521 @default.
• W2000573877 hasRelatedWork W2143941942 @default.
• W2000573877 hasRelatedWork W2146341506 @default.
• W2000573877 hasRelatedWork W2358663732 @default.
• W2000573877 hasRelatedWork W2421589566 @default.
• W2000573877 hasRelatedWork W2901237116 @default.
• W2000573877 hasRelatedWork W4302424555 @default.
• W2000573877 hasRelatedWork W4308683315 @default.
• W2000573877 hasVolume "31" @default.
• W2000573877 isParatext "false" @default.
• W2000573877 isRetracted "false" @default.
• W2000573877 magId "2000573877" @default.
• W2000573877 workType "article" @default.