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• W2000577920 abstract "We previously reported that rabies virus strain CE(NiM), but not the parental Ni-CE strain, killed mice after intracerebral inoculation. CE(NiM) and Ni-CE are genetically identical except for two amino acids at positions 29 and 95 in the M protein. In this study, to identify which residue determines the pathogenicity, we examined pathogenicities of two Ni-CE mutants, CE(NiM29) and CE(NiM95), which were established by replacement of an amino acid residue at position 29 or 95 in the Ni-CE M protein with the corresponding residue of CE(NiM), respectively. We found that CE(NiM95), but not CE(NiM29), killed mice, indicating that the amino acid at position 95 in the M protein is the pathogenic determinant." @default.
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• W2000577920 date "2011-01-01" @default.
• W2000577920 modified "2023-09-27" @default.
• W2000577920 title "Amino Acid Substitution at Position 95 in Rabies Virus Matrix Protein Affects Viral Pathogenicity" @default.
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• W2000577920 doi "https://doi.org/10.1292/jvms.11-0151" @default.
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