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- W2000578756 abstract "Temperature sensitive poly(N-isopropylacrylamide) (PIPAAM) was incorporated into hepatocyte-recognizable poly[N-p-vinylbenzyl-O-β-D-galactopyranosyl-(1 → 4)-D-gluconamide] (PVLA) for thermal modulating of hepatocyte attachment. The copolymer, poly(N-isopropylacrylamide-co-N-p-vinylbenzyl-O-β-D-galactopyranosyl-(1 → 4)-D-gluconamide) (abbreviated as [P(IPAAM-co-VLA)] (PIPAAM/PVLA = 9/1 in mol%) exhibited lower critical solution temperature (LCST) at 34°C and also showed very good hepatocytes-recognizablility through the specific interaction between asialoglycoprotein receptors on the cell surfaces and galactose moiety of the copolymer. The cells attached on this copolymer were easily detached by lowering the temperature below the LCST of the copolymer. Morphological damage of the detached cell was not observed." @default.
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- W2000578756 date "2001-01-01" @default.
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- W2000578756 title "Hepatocyte attachment onto thermosensitive poly(N-isopropylacrylamide co-N-p-vinylbenzyl-O -β-D-galactopyranosyl(1 → 4)-D-gluconamide)" @default.
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- W2000578756 doi "https://doi.org/10.1163/156856201750411648" @default.
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