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• W2000579532 startingPage "79" @default.
• W2000579532 abstract "The current study established a procedure to evaluate the capability of rats on postnatal days (PND) 21, 26, and 30 to perform a spatial serial reversal task using a T-maze. Training consisted of an acquisition session followed by a series of six reversal sessions. To examine the role of proactive interference in the serial reversal effect, the point of reversal was manipulated so that it occurred at the start of each session (between-sessions) or the midpoint of each session (within-sessions). Performance was initially impaired during the first reversal but improved dramatically across the series. Reversal between-sessions enhanced this serial reversal effect in comparison to reversal within-sessions. Experiment 1 showed that rats of all ages learned the between-sessions serial reversal task at a comparable rate. However, on the within-sessions task, PND21 rats were impaired relative to the PND26 and 30 rats, which did not differ. Experiment 2 revealed that the addition of a tactile cue that is correlated with each phase of reversal eliminated age and task differences in serial reversal performance. These findings suggest that higher-order cognitive processes underlying serial reversal are present during the weanling period, but there is some improvement with age under conditions involving high memory interference and/or difficulty in detecting the transition between reversal phases. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 48: 79–94, 2006." @default.
• W2000579532 created "2016-06-24" @default.
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• W2000579532 date "2005-01-01" @default.
• W2000579532 modified "2023-09-24" @default.
• W2000579532 title "Serial reversal learning of position discrimination in developing rats" @default.
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• W2000579532 doi "https://doi.org/10.1002/dev.20106" @default.
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