FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000580036> ?p ?o ?g. }

• W2000580036 endingPage "1465" @default.
• W2000580036 startingPage "1457" @default.
• W2000580036 abstract "Abstract Nitric oxide (NO) is a key neuromodulator of corticostriatal synaptic transmission. We have shown previously that dopamine (DA) D1/5 receptor stimulation facilitates neuronal NO synthase (nNOS) activity in the intact striatum. To study the impact of local manipulations of D1/5 and glutamatergic NMDA receptors on striatal nNOS activity, we combined the techniques of in vivo amperometry and reverse microdialysis. Striatal NO efflux was monitored proximal to the microdialysis probe in urethane‐anesthetized rats during local infusion of vehicle or drug. NO efflux elicited by systemic administration of SKF‐81297 was blocked following intrastriatal infusion of: (i) the D1/5 receptor antagonist SCH‐23390, (ii) the nNOS inhibitor 7‐nitroindazole, (iii) the non‐specific ionotropic glutamate receptor antagonist kynurenic acid, and (iv) the selective NMDA receptor antagonist 3‐phosphonopropyl‐piperazine‐2‐carboxylic acid. Glycine co‐perfusion did not affect SKF‐81297‐induced NO efflux. Furthermore, intrastriatal infusion of SKF‐81297 potentiated NO efflux evoked during electrical stimulation of the motor cortex. The facilitatory effects of cortical stimulation and SKF‐81297 were both blocked by intrastriatal infusion of SCH‐23390, indicating that striatal D1/5 receptor activation is necessary for the activation of nNOS by corticostriatal afferents. These studies demonstrate for the first time that reciprocal DA‐glutamate interactions play a critical role in stimulating striatal nNOS activity." @default.
• W2000580036 created "2016-06-24" @default.
• W2000580036 creator A5041430059 @default.
• W2000580036 creator A5061592030 @default.
• W2000580036 date "2009-11-20" @default.
• W2000580036 modified "2023-10-16" @default.
• W2000580036 title "Regulation of striatal nitric oxide synthesis by local dopamine and glutamate interactions" @default.
• W2000580036 cites W1519147845 @default.
• W2000580036 cites W1634005937 @default.
• W2000580036 cites W1943649468 @default.
• W2000580036 cites W1964708390 @default.
• W2000580036 cites W1966613533 @default.
• W2000580036 cites W1968228025 @default.
• W2000580036 cites W1970163951 @default.
• W2000580036 cites W1974931223 @default.
• W2000580036 cites W1978648371 @default.
• W2000580036 cites W1979505376 @default.
• W2000580036 cites W1982743710 @default.
• W2000580036 cites W1985107882 @default.
• W2000580036 cites W1991469904 @default.
• W2000580036 cites W1993555245 @default.
• W2000580036 cites W1994639520 @default.
• W2000580036 cites W1999238877 @default.
• W2000580036 cites W2004548085 @default.
• W2000580036 cites W2012385732 @default.
• W2000580036 cites W2018086192 @default.
• W2000580036 cites W2020034315 @default.
• W2000580036 cites W2024862570 @default.
• W2000580036 cites W2026623916 @default.
• W2000580036 cites W2026709325 @default.
• W2000580036 cites W2028468118 @default.
• W2000580036 cites W2030711307 @default.
• W2000580036 cites W2032250924 @default.
• W2000580036 cites W2033362290 @default.
• W2000580036 cites W2033932350 @default.
• W2000580036 cites W2038754384 @default.
• W2000580036 cites W2042329023 @default.
• W2000580036 cites W2044194267 @default.
• W2000580036 cites W2045417237 @default.
• W2000580036 cites W2047652027 @default.
• W2000580036 cites W2050720223 @default.
• W2000580036 cites W2058077554 @default.
• W2000580036 cites W2059775362 @default.
• W2000580036 cites W2060599083 @default.
• W2000580036 cites W2061570824 @default.
• W2000580036 cites W2065442842 @default.
• W2000580036 cites W2067737211 @default.
• W2000580036 cites W2084451367 @default.
• W2000580036 cites W2084838390 @default.
• W2000580036 cites W2091257171 @default.
• W2000580036 cites W2092210394 @default.
• W2000580036 cites W2094007091 @default.
• W2000580036 cites W2103305184 @default.
• W2000580036 cites W2105482032 @default.
• W2000580036 cites W2116380401 @default.
• W2000580036 cites W2118937742 @default.
• W2000580036 cites W2123581158 @default.
• W2000580036 cites W2124168630 @default.
• W2000580036 cites W2131586229 @default.
• W2000580036 cites W2135166711 @default.
• W2000580036 cites W2144157663 @default.
• W2000580036 cites W2148561831 @default.
• W2000580036 cites W2152553016 @default.
• W2000580036 cites W2153961293 @default.
• W2000580036 cites W215484544 @default.
• W2000580036 cites W2164784351 @default.
• W2000580036 cites W2170597465 @default.
• W2000580036 cites W2171584675 @default.
• W2000580036 cites W2172527495 @default.
• W2000580036 cites W4234401654 @default.
• W2000580036 cites W4245212867 @default.
• W2000580036 cites W4317929355 @default.
• W2000580036 doi "https://doi.org/10.1111/j.1471-4159.2009.06416.x" @default.
• W2000580036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2796709" @default.
• W2000580036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19799710" @default.
• W2000580036 hasPublicationYear "2009" @default.
• W2000580036 type Work @default.
• W2000580036 sameAs 2000580036 @default.
• W2000580036 citedByCount "39" @default.
• W2000580036 countsByYear W20005800362012 @default.
• W2000580036 countsByYear W20005800362013 @default.
• W2000580036 countsByYear W20005800362014 @default.
• W2000580036 countsByYear W20005800362015 @default.
• W2000580036 countsByYear W20005800362016 @default.
• W2000580036 countsByYear W20005800362017 @default.
• W2000580036 countsByYear W20005800362019 @default.
• W2000580036 countsByYear W20005800362020 @default.
• W2000580036 countsByYear W20005800362023 @default.
• W2000580036 crossrefType "journal-article" @default.
• W2000580036 hasAuthorship W2000580036A5041430059 @default.
• W2000580036 hasAuthorship W2000580036A5061592030 @default.
• W2000580036 hasBestOaLocation W20005800362 @default.
• W2000580036 hasConcept C160268369 @default.
• W2000580036 hasConcept C169760540 @default.
• W2000580036 hasConcept C170493617 @default.
• W2000580036 hasConcept C185592680 @default.
• W2000580036 hasConcept C2776841986 @default.
• W2000580036 hasConcept C2778938600 @default.

• next