Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000580951> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2000580951 endingPage "159" @default.
- W2000580951 startingPage "159" @default.
- W2000580951 abstract "CONVENTIONAL randomized clinical trials of new treatments usually rely on clinical end points that directly show the effect of the new treatment on outcomes such as quality or length of life. In chronic diseases, like cancer, cardiovascular disease, and human immunodeficiency virus (HIV) infection, standard clinical end points may be either distant in time or rare, and thus require a trial of long duration, large sample size, or both to demonstrate the value of a new treatment. A surrogate marker for that clinical end point would allow more rapid completion of clinical investigations of new therapies. The use of surrogate markers in evaluating effective therapies for HIV infection has drawn considerable attention. See also pp 158 and 161. A perfect surrogate marker for use in the study of a new therapeutic agent must be biologically plausible, measurable in all patients with the disease, predictive of disease progression (ie, worsening with" @default.
- W2000580951 created "2016-06-24" @default.
- W2000580951 creator A5041754237 @default.
- W2000580951 date "1996-07-10" @default.
- W2000580951 modified "2023-10-16" @default.
- W2000580951 title "Importance of Surrogate Markers in Evaluation of Antiviral Therapy for HIV Infection" @default.
- W2000580951 cites W1973398091 @default.
- W2000580951 cites W1979300114 @default.
- W2000580951 cites W1983112408 @default.
- W2000580951 cites W2011630381 @default.
- W2000580951 cites W2016564963 @default.
- W2000580951 cites W2020096299 @default.
- W2000580951 cites W2021037491 @default.
- W2000580951 cites W2042411177 @default.
- W2000580951 cites W2065114401 @default.
- W2000580951 cites W2093801705 @default.
- W2000580951 cites W2099352670 @default.
- W2000580951 cites W2136282054 @default.
- W2000580951 cites W2142257518 @default.
- W2000580951 cites W2148774347 @default.
- W2000580951 cites W2155949904 @default.
- W2000580951 cites W2314098905 @default.
- W2000580951 cites W2318770038 @default.
- W2000580951 cites W2323021547 @default.
- W2000580951 cites W2339827976 @default.
- W2000580951 cites W2340851790 @default.
- W2000580951 cites W2406890504 @default.
- W2000580951 cites W2435538673 @default.
- W2000580951 doi "https://doi.org/10.1001/jama.1996.03540020081034" @default.
- W2000580951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8656509" @default.
- W2000580951 hasPublicationYear "1996" @default.
- W2000580951 type Work @default.
- W2000580951 sameAs 2000580951 @default.
- W2000580951 citedByCount "17" @default.
- W2000580951 countsByYear W20005809512012 @default.
- W2000580951 countsByYear W20005809512013 @default.
- W2000580951 countsByYear W20005809512015 @default.
- W2000580951 crossrefType "journal-article" @default.
- W2000580951 hasAuthorship W2000580951A5041754237 @default.
- W2000580951 hasConcept C126322002 @default.
- W2000580951 hasConcept C141341695 @default.
- W2000580951 hasConcept C143998085 @default.
- W2000580951 hasConcept C168563851 @default.
- W2000580951 hasConcept C177713679 @default.
- W2000580951 hasConcept C203014093 @default.
- W2000580951 hasConcept C203092338 @default.
- W2000580951 hasConcept C2779134260 @default.
- W2000580951 hasConcept C3013748606 @default.
- W2000580951 hasConcept C535046627 @default.
- W2000580951 hasConcept C71924100 @default.
- W2000580951 hasConceptScore W2000580951C126322002 @default.
- W2000580951 hasConceptScore W2000580951C141341695 @default.
- W2000580951 hasConceptScore W2000580951C143998085 @default.
- W2000580951 hasConceptScore W2000580951C168563851 @default.
- W2000580951 hasConceptScore W2000580951C177713679 @default.
- W2000580951 hasConceptScore W2000580951C203014093 @default.
- W2000580951 hasConceptScore W2000580951C203092338 @default.
- W2000580951 hasConceptScore W2000580951C2779134260 @default.
- W2000580951 hasConceptScore W2000580951C3013748606 @default.
- W2000580951 hasConceptScore W2000580951C535046627 @default.
- W2000580951 hasConceptScore W2000580951C71924100 @default.
- W2000580951 hasIssue "2" @default.
- W2000580951 hasLocation W20005809511 @default.
- W2000580951 hasLocation W20005809512 @default.
- W2000580951 hasOpenAccess W2000580951 @default.
- W2000580951 hasPrimaryLocation W20005809511 @default.
- W2000580951 hasRelatedWork W1852785632 @default.
- W2000580951 hasRelatedWork W2089903975 @default.
- W2000580951 hasRelatedWork W2169374891 @default.
- W2000580951 hasRelatedWork W2297790284 @default.
- W2000580951 hasRelatedWork W2601979671 @default.
- W2000580951 hasRelatedWork W2611353607 @default.
- W2000580951 hasRelatedWork W3025555446 @default.
- W2000580951 hasRelatedWork W3080304190 @default.
- W2000580951 hasRelatedWork W3089163820 @default.
- W2000580951 hasRelatedWork W3138366407 @default.
- W2000580951 hasVolume "276" @default.
- W2000580951 isParatext "false" @default.
- W2000580951 isRetracted "false" @default.
- W2000580951 magId "2000580951" @default.
- W2000580951 workType "article" @default.