FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000584624> ?p ?o ?g. }

• W2000584624 endingPage "2913" @default.
• W2000584624 startingPage "2904" @default.
• W2000584624 abstract "It was recently demonstrated that significant local deformations of biological membranes take place due to the fields of charged peptides and ions, challenging the standard model of membrane electrostatics. The ability of ions to retain their immediate hydration environment, combined with the lack of sensitivity of permeability to ion type or even ion pairs, led us to question the extent to which hydration energetics and electrostatics control membrane ion permeation. Using the arginine analog methyl-guanidinium as a test case, we find that although hydrocarbon electronic polarizability causes dramatic changes in ion solvation free energy, as well as a significant change (∼0.4 V) in the membrane dipole potential, little change in membrane permeation energetics occurs. We attribute this to compensation of solvation terms from polar and polarizable nonpolar components within the membrane, and explain why the dipole potential is not fully sensed in terms of the locally deformed bilayer interface. Our descriptions provide a deeper understanding of the translocation process and allow predictions for poly-ions, ion pairs, charged lipids, and lipid flip-flop. We also report simulations of large hydrophobic-ion-like membrane defects and the ionophore valinomycin, which exhibit little membrane deformation, as well as hydrophilic defects and the ion channel gramicidin A, to provide parallels to membranes deformed by unassisted ion permeation." @default.
• W2000584624 created "2016-06-24" @default.
• W2000584624 creator A5031310158 @default.
• W2000584624 creator A5038015825 @default.
• W2000584624 creator A5068923509 @default.
• W2000584624 date "2010-06-01" @default.
• W2000584624 modified "2023-10-17" @default.
• W2000584624 title "Electrostatics of Deformable Lipid Membranes" @default.
• W2000584624 cites W1824377481 @default.
• W2000584624 cites W1963836201 @default.
• W2000584624 cites W1973889696 @default.
• W2000584624 cites W1980963182 @default.
• W2000584624 cites W1982898268 @default.
• W2000584624 cites W1984014838 @default.
• W2000584624 cites W1984356759 @default.
• W2000584624 cites W1990451546 @default.
• W2000584624 cites W1991655565 @default.
• W2000584624 cites W1993692047 @default.
• W2000584624 cites W1995159519 @default.
• W2000584624 cites W1995229360 @default.
• W2000584624 cites W1995960546 @default.
• W2000584624 cites W1996685148 @default.
• W2000584624 cites W2000998941 @default.
• W2000584624 cites W2001303516 @default.
• W2000584624 cites W2015324838 @default.
• W2000584624 cites W2015835531 @default.
• W2000584624 cites W2019036104 @default.
• W2000584624 cites W2021125439 @default.
• W2000584624 cites W2021283978 @default.
• W2000584624 cites W2022072508 @default.
• W2000584624 cites W2022309859 @default.
• W2000584624 cites W2024982125 @default.
• W2000584624 cites W2025345929 @default.
• W2000584624 cites W2026889256 @default.
• W2000584624 cites W2027296812 @default.
• W2000584624 cites W2027408247 @default.
• W2000584624 cites W2029667189 @default.
• W2000584624 cites W2030143885 @default.
• W2000584624 cites W2037462822 @default.
• W2000584624 cites W2038444883 @default.
• W2000584624 cites W2041945676 @default.
• W2000584624 cites W2053116433 @default.
• W2000584624 cites W2055154757 @default.
• W2000584624 cites W2061969981 @default.
• W2000584624 cites W2070677527 @default.
• W2000584624 cites W2076515696 @default.
• W2000584624 cites W2078884620 @default.
• W2000584624 cites W2082204764 @default.
• W2000584624 cites W2086448463 @default.
• W2000584624 cites W2086714797 @default.
• W2000584624 cites W2091240944 @default.
• W2000584624 cites W2102640727 @default.
• W2000584624 cites W2109677076 @default.
• W2000584624 cites W2114524505 @default.
• W2000584624 cites W2118733096 @default.
• W2000584624 cites W2118884279 @default.
• W2000584624 cites W2121138440 @default.
• W2000584624 cites W2121936687 @default.
• W2000584624 cites W2152270594 @default.
• W2000584624 cites W2162166182 @default.
• W2000584624 doi "https://doi.org/10.1016/j.bpj.2010.03.046" @default.
• W2000584624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2884252" @default.
• W2000584624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20550903" @default.
• W2000584624 hasPublicationYear "2010" @default.
• W2000584624 type Work @default.
• W2000584624 sameAs 2000584624 @default.
• W2000584624 citedByCount "44" @default.
• W2000584624 countsByYear W20005846242012 @default.
• W2000584624 countsByYear W20005846242013 @default.
• W2000584624 countsByYear W20005846242014 @default.
• W2000584624 countsByYear W20005846242015 @default.
• W2000584624 countsByYear W20005846242016 @default.
• W2000584624 countsByYear W20005846242017 @default.
• W2000584624 countsByYear W20005846242018 @default.
• W2000584624 countsByYear W20005846242019 @default.
• W2000584624 countsByYear W20005846242021 @default.
• W2000584624 countsByYear W20005846242022 @default.
• W2000584624 countsByYear W20005846242023 @default.
• W2000584624 crossrefType "journal-article" @default.
• W2000584624 hasAuthorship W2000584624A5031310158 @default.
• W2000584624 hasAuthorship W2000584624A5038015825 @default.
• W2000584624 hasAuthorship W2000584624A5068923509 @default.
• W2000584624 hasBestOaLocation W20005846241 @default.
• W2000584624 hasConcept C117626034 @default.
• W2000584624 hasConcept C12554922 @default.
• W2000584624 hasConcept C139287275 @default.
• W2000584624 hasConcept C145148216 @default.
• W2000584624 hasConcept C147789679 @default.
• W2000584624 hasConcept C148093993 @default.
• W2000584624 hasConcept C159467904 @default.
• W2000584624 hasConcept C170493617 @default.
• W2000584624 hasConcept C173523689 @default.
• W2000584624 hasConcept C178790620 @default.
• W2000584624 hasConcept C185592680 @default.
• W2000584624 hasConcept C2778385715 @default.
• W2000584624 hasConcept C32909587 @default.
• W2000584624 hasConcept C39944091 @default.
• W2000584624 hasConcept C41625074 @default.

• next